Protein: ENSP00000361066
Gene: NCOA3

LinkedOmicsKB © 2022-2023 Zhang Lab

NCOA3:
nuclear receptor coactivator 3

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Structure

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

Loading, please wait
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S32PGQGLTCSGEKRRRE219--------7354--------
S214ILEDINASPEMRQRY101364122-2925939599-1086210394110101751888378916
S306RCIQRFFSLNDGQSW124------------------186
S551PGPKLDNSPNMNITQ10118590-7468646173-7846898211010113392398418
S567SKVSNQDSKSPLGFY18--44----------------
S569VSNQDSKSPLGFYCD10130185-8270294299-1035810395110100731389379518
Y574SKSPLGFYCDQNPVE861987-36192222--27149890878017794--
S636SDDRGHSSLTNSPLD8202--881628--634036981955110-
T638DRGHSSLTNSPLDSS119----------109--------
S640GHSSLTNSPLDSSCK1051421-2524283436-5832545043681551587
Showing 1 to 10 of 23 rows
1025
rows per page

Tumor and normal comparison

Loading, please wait
Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S32PGQGLTCSGEKRRRE-----------
S214ILEDINASPEMRQRY0.082-0.11-3.2e-4-0.0541.0e-40.65-0.6-0.580.077
S306RCIQRFFSLNDGQSW-----------
S551PGPKLDNSPNMNITQ1.2e-4--1.4e-40.036-5.3e-31.4e-77.1e-10--0.32-0.18
S567SKVSNQDSKSPLGFY-----------
S569VSNQDSKSPLGFYCD7.8e-14--0.343.3e-6-0.631.8e-150.570.0552.9e-60.068
Y574SKSPLGFYCDQNPVE2.3e-14--0.0464.3e-3-0.0114.4e-156.1e-9---
S636SDDRGHSSLTNSPLD0.68-----0.68----
T638DRGHSSLTNSPLDSS-----------
S640GHSSLTNSPLDSSCK2.2e-7--2.6e-42.7e-4-0.001-1.3e-65.1e-4--
Showing 1 to 10 of 23 rows
1025
rows per page

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

Loading, please wait
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAS32S214S306S551S567S569Y574S636T638S640S655S694S728S778S836S857S860S863S866S867S967S1033S1330proteinRNASCNVmethylationCCRCCS32S214S306S551S567S569Y574S636T638S640S655S694S728S778S836S857S860S863S866S867S967S1033S1330proteinRNASCNVmethylationCOADS32S214S306S551S567S569Y574S636T638S640S655S694S728S778S836S857S860S863S866S867S967S1033S1330proteinRNASCNVmethylationGBMS32S214S306S551S567S569Y574S636T638S640S655S694S728S778S836S857S860S863S866S867S967S1033S1330proteinRNASCNVmethylationHNSCCS32S214S306S551S567S569Y574S636T638S640S655S694S728S778S836S857S860S863S866S867S967S1033S1330proteinRNASCNVmethylationLSCCS32S214S306S551S567S569Y574S636T638S640S655S694S728S778S836S857S860S863S866S867S967S1033S1330proteinRNASCNVmethylationLUADS32S214S306S551S567S569Y574S636T638S640S655S694S728S778S836S857S860S863S866S867S967S1033S1330proteinRNASCNVmethylationOVS32S214S306S551S567S569Y574S636T638S640S655S694S728S778S836S857S860S863S866S867S967S1033S1330proteinRNASCNVmethylationPDACS32S214S306S551S567S569Y574S636T638S640S655S694S728S778S836S857S860S863S866S867S967S1033S1330proteinRNASCNVmethylationUCECS32S214S306S551S567S569Y574S636T638S640S655S694S728S778S836S857S860S863S866S867S967S1033S1330proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

Loading, please wait
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

Loading, please wait
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.