BMPR1A: bone morphogenetic protein receptor type 1A
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
1es7 chain B
1es7 chain D
1rew chain C
1rew chain D
2goo chain B
2goo chain E
2h62 chain C
2h64 chain B
2k3g chain A
2qj9 chain C
2qj9 chain D
2qja chain C
2qja chain D
2qjb chain C
2qjb chain D
3nh7 chain A
3nh7 chain B
3nh7 chain C
3nh7 chain D
3qb4 chain B
3qb4 chain D
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S205 AFIPVGES LKDLIDQ 4 97 - - - - - - 9 - - - 29 25 5 4 - - - - 21 4 S375 ILIKKNGS CCIADLG 1 18 - - - - - - - - - - - - - - - - - - 18 -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S205 AFIPVGES LKDLIDQ -0.33 - - - - - -0.33 - - - - S375 ILIKKNGS CCIADLG - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S205
S375
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S205 S375 protein RNA SCNV methylation CCRCC S205 S375 protein RNA SCNV methylation COAD S205 S375 protein RNA SCNV methylation GBM S205 S375 protein RNA SCNV methylation HNSCC S205 S375 protein RNA SCNV methylation LSCC S205 S375 protein RNA SCNV methylation LUAD S205 S375 protein RNA SCNV methylation OV S205 S375 protein RNA SCNV methylation PDAC S205 S375 protein RNA SCNV methylation UCEC S205 S375 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S205
S375
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S205
S375
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.