DLG5: discs large MAGUK scaffold protein 5
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S132 GTTGKAPS PPPLLTD 9 608 15 - 64 44 - - 19 - 67 39 44 39 26 25 37 7 63 25 76 18 S150 NEKVENLS IQLRLMT 1 7 7 - - - - - - - - - - - - - - - - - - - S200 IQCVRAMS DLQSLQN 1 7 - - - - - - - - - - - - - - - - - - 7 - S204 RAMSDLQS LQNQHTN 1 8 8 - - - - - - - - - - - - - - - - - - - S235 TLHSRLLS DQTRLKD 1 17 - - - - - - - - - - - - - - - - - - 5 12 S264 ERNLLQQS WEDMKRL 10 1356 122 - 99 76 52 47 99 - 97 55 103 95 106 96 47 12 97 40 95 18 S295 QVLKHNGS SEILNKL 10 380 8 - 13 12 24 21 54 - 11 5 25 24 12 12 54 14 9 3 70 9 S296 VLKHNGSS EILNKLY 4 42 8 - - - 7 2 - - 11 7 - - - - - - - - 7 - S604 RQLMAHSS HDSAIDT 1 9 9 - - - - - - - - - - - - - - - - - - - S607 MAHSSHDS AIDTDSM 1 9 9 - - - - - - - - - - - - - - - - - - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S132 GTTGKAPS PPPLLTD -0.11 - 0.98 - - -0.052 -0.85 -0.04 - -0.86 0.68 S150 NEKVENLS IQLRLMT - - - - - - - - - - - S200 IQCVRAMS DLQSLQN - - - - - - - - - - - S204 RAMSDLQS LQNQHTN - - - - - - - - - - - S235 TLHSRLLS DQTRLKD - - - - - - - - - - - S264 ERNLLQQS WEDMKRL 5.6e-38 - 0.23 2.7e-4 - 5.2e-5 2e-29 7.5e-30 0.77 3.8e-14 -3.4e-3 S295 QVLKHNGS SEILNKL 0.013 - - 0.24 - - 1.5e-4 - -0.5 - - S296 VLKHNGSS EILNKLY - - - - - - - - - - - S604 RQLMAHSS HDSAIDT - - - - - - - - - - - S607 MAHSSHDS AIDTDSM - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S132
S150
S200
S204
S235
S264
S295
S296
S604
S607
T718
S747
S791
S801
S803
S814
S841
T842
S864
S865
S886
S888
S891
S897
S900
S932
S938
S941
S943
T946
S972
T984
Y990
S1000
T1011
S1021
S1034
T1045
S1064
S1075
S1093
S1115
S1146
Y1155
S1156
T1183
S1209
S1224
S1232
S1241
S1252
S1254
S1263
S1264
S1265
T1279
T1301
S1305
S1334
S1357
T1406
T1479
Y1550
S1552
S1666
S1795
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S132 S150 S200 S204 S235 S264 S295 S296 S604 S607 T718 S747 S791 S801 S803 S814 S841 T842 S864 S865 S886 S888 S891 S897 S900 S932 S938 S941 S943 T946 S972 T984 Y990 S1000 T1011 S1021 S1034 T1045 S1064 S1075 S1093 S1115 S1146 Y1155 S1156 T1183 S1209 S1224 S1232 S1241 S1252 S1254 S1263 S1264 S1265 T1279 T1301 S1305 S1334 T1406 T1479 Y1550 S1552 S1666 S1795 protein RNA SCNV methylation CCRCC S132 S150 S200 S204 S235 S264 S295 S296 S604 S607 T718 S747 S791 S801 S803 S814 S841 T842 S864 S865 S886 S888 S891 S897 S900 S932 S938 S941 S943 T946 S972 T984 Y990 S1000 T1011 S1021 S1034 T1045 S1064 S1075 S1093 S1115 S1146 Y1155 S1156 T1183 S1209 S1224 S1232 S1241 S1252 S1254 S1263 S1264 S1265 T1279 T1301 S1305 S1334 T1406 T1479 Y1550 S1552 S1666 S1795 protein RNA SCNV methylation COAD S132 S150 S200 S204 S235 S264 S295 S296 S604 S607 T718 S747 S791 S801 S803 S814 S841 T842 S864 S865 S886 S888 S891 S897 S900 S932 S938 S941 S943 T946 S972 T984 Y990 S1000 T1011 S1021 S1034 T1045 S1064 S1075 S1093 S1115 S1146 Y1155 S1156 T1183 S1209 S1224 S1232 S1241 S1252 S1254 S1263 S1264 S1265 T1279 T1301 S1305 S1334 T1406 T1479 Y1550 S1552 S1666 S1795 protein RNA SCNV methylation GBM S132 S150 S200 S204 S235 S264 S295 S296 S604 S607 T718 S747 S791 S801 S803 S814 S841 T842 S864 S865 S886 S888 S891 S897 S900 S932 S938 S941 S943 T946 S972 T984 Y990 S1000 T1011 S1021 S1034 T1045 S1064 S1075 S1093 S1115 S1146 Y1155 S1156 T1183 S1209 S1224 S1232 S1241 S1252 S1254 S1263 S1264 S1265 T1279 T1301 S1305 S1334 T1406 T1479 Y1550 S1552 S1666 S1795 protein RNA SCNV methylation HNSCC S132 S150 S200 S204 S235 S264 S295 S296 S604 S607 T718 S747 S791 S801 S803 S814 S841 T842 S864 S865 S886 S888 S891 S897 S900 S932 S938 S941 S943 T946 S972 T984 Y990 S1000 T1011 S1021 S1034 T1045 S1064 S1075 S1093 S1115 S1146 Y1155 S1156 T1183 S1209 S1224 S1232 S1241 S1252 S1254 S1263 S1264 S1265 T1279 T1301 S1305 S1334 T1406 T1479 Y1550 S1552 S1666 S1795 protein RNA SCNV methylation LSCC S132 S150 S200 S204 S235 S264 S295 S296 S604 S607 T718 S747 S791 S801 S803 S814 S841 T842 S864 S865 S886 S888 S891 S897 S900 S932 S938 S941 S943 T946 S972 T984 Y990 S1000 T1011 S1021 S1034 T1045 S1064 S1075 S1093 S1115 S1146 Y1155 S1156 T1183 S1209 S1224 S1232 S1241 S1252 S1254 S1263 S1264 S1265 T1279 T1301 S1305 S1334 T1406 T1479 Y1550 S1552 S1666 S1795 protein RNA SCNV methylation LUAD S132 S150 S200 S204 S235 S264 S295 S296 S604 S607 T718 S747 S791 S801 S803 S814 S841 T842 S864 S865 S886 S888 S891 S897 S900 S932 S938 S941 S943 T946 S972 T984 Y990 S1000 T1011 S1021 S1034 T1045 S1064 S1075 S1093 S1115 S1146 Y1155 S1156 T1183 S1209 S1224 S1232 S1241 S1252 S1254 S1263 S1264 S1265 T1279 T1301 S1305 S1334 T1406 T1479 Y1550 S1552 S1666 S1795 protein RNA SCNV methylation OV S132 S150 S200 S204 S235 S264 S295 S296 S604 S607 T718 S747 S791 S801 S803 S814 S841 T842 S864 S865 S886 S888 S891 S897 S900 S932 S938 S941 S943 T946 S972 T984 Y990 S1000 T1011 S1021 S1034 T1045 S1064 S1075 S1093 S1115 S1146 Y1155 S1156 T1183 S1209 S1224 S1232 S1241 S1252 S1254 S1263 S1264 S1265 T1279 T1301 S1305 S1334 T1406 T1479 Y1550 S1552 S1666 S1795 protein RNA SCNV methylation PDAC S132 S150 S200 S204 S235 S264 S295 S296 S604 S607 T718 S747 S791 S801 S803 S814 S841 T842 S864 S865 S886 S888 S891 S897 S900 S932 S938 S941 S943 T946 S972 T984 Y990 S1000 T1011 S1021 S1034 T1045 S1064 S1075 S1093 S1115 S1146 Y1155 S1156 T1183 S1209 S1224 S1232 S1241 S1252 S1254 S1263 S1264 S1265 T1279 T1301 S1305 S1334 T1406 T1479 Y1550 S1552 S1666 S1795 protein RNA SCNV methylation UCEC S132 S150 S200 S204 S235 S264 S295 S296 S604 S607 T718 S747 S791 S801 S803 S814 S841 T842 S864 S865 S886 S888 S891 S897 S900 S932 S938 S941 S943 T946 S972 T984 Y990 S1000 T1011 S1021 S1034 T1045 S1064 S1075 S1093 S1115 S1146 Y1155 S1156 T1183 S1209 S1224 S1232 S1241 S1252 S1254 S1263 S1264 S1265 T1279 T1301 S1305 S1334 T1406 T1479 Y1550 S1552 S1666 S1795 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S132
S150
S200
S204
S235
S264
S295
S296
S604
S607
T718
S747
S791
S801
S803
S814
S841
T842
S864
S865
S886
S888
S891
S897
S900
S932
S938
S941
S943
T946
S972
T984
Y990
S1000
T1011
S1021
S1034
T1045
S1064
S1075
S1093
S1115
S1146
Y1155
S1156
T1183
S1209
S1224
S1232
S1241
S1252
S1254
S1263
S1264
S1265
T1279
T1301
S1305
S1334
S1357
T1406
T1479
Y1550
S1552
S1666
S1795
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
Loading, please wait
all sites
S132
S150
S200
S204
S235
S264
S295
S296
S604
S607
T718
S747
S791
S801
S803
S814
S841
T842
S864
S865
S886
S888
S891
S897
S900
S932
S938
S941
S943
T946
S972
T984
Y990
S1000
T1011
S1021
S1034
T1045
S1064
S1075
S1093
S1115
S1146
Y1155
S1156
T1183
S1209
S1224
S1232
S1241
S1252
S1254
S1263
S1264
S1265
T1279
T1301
S1305
S1334
S1357
T1406
T1479
Y1550
S1552
S1666
S1795
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.