- CAP1:
- cyclase associated actin cytoskeleton regulatory protein 1
Lollipop plot
Phosphosites location and occurrence
Structure
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
BRCA | CCRCC | COAD | GBM | HNSCC | LSCC | LUAD | OV | PDAC | UCEC | ||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Site
| Sequence | Cohorts | Total | T | N | T | N | T | N | T | N | T | N | T | N | T | N | T | N | T | N | T | N |
S25 | LEAVSHTSDMHRGYA | 4 | 151 | - | - | - | - | - | - | 90 | - | - | - | 15 | 14 | 10 | 8 | - | - | - | - | 12 | 2 |
S34 | MHRGYADSPSKAGAA | 8 | 1063 | - | - | 85 | 67 | - | - | 81 | - | 103 | 59 | 84 | 77 | 87 | 81 | 76 | 17 | 93 | 40 | 95 | 18 |
S36 | RGYADSPSKAGAAPY | 5 | 149 | - | - | 17 | 15 | - | - | - | - | - | - | 24 | 23 | 19 | 15 | - | - | 20 | 7 | 7 | 2 |
S49 | PYVQAFDSLLAGPVA | 5 | 265 | - | - | 57 | 37 | - | - | 28 | - | 70 | 37 | 5 | 5 | 14 | 12 | - | - | - | - | - | - |
S91 | RALLVTASQCQQPAE | 4 | 49 | - | - | - | - | - | - | - | - | - | - | 5 | 4 | 9 | 9 | - | - | 5 | 2 | 13 | 2 |
S102 | QPAENKLSDLLAPIS | 3 | 96 | - | - | 5 | 4 | - | - | - | - | - | - | 15 | 13 | 30 | 29 | - | - | - | - | - | - |
S275 | THALKHVSDDMKTHK | 8 | 610 | - | - | 16 | 8 | - | - | 63 | - | 18 | 10 | 90 | 81 | 88 | 82 | 7 | 2 | 31 | 14 | 84 | 16 |
S290 | NPALKAQSGPVRSGP | 2 | 45 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 7 | 1 | 25 | 12 | - | - |
S295 | AQSGPVRSGPKPFSA | 7 | 704 | - | - | 87 | 67 | - | - | 62 | - | 97 | 54 | 20 | 18 | 83 | 76 | - | - | 72 | 30 | 35 | 3 |
S301 | RSGPKPFSAPKPQTS | 3 | 23 | - | - | - | - | - | - | - | - | - | - | 5 | 5 | - | - | - | - | 3 | 2 | 8 | - |
Tumor and normal comparison
Site
| Sequence | Meta P | BRCA | CCRCC | COAD | GBM | HNSCC | LSCC | LUAD | OV | PDAC | UCEC |
---|---|---|---|---|---|---|---|---|---|---|---|---|
S25 | LEAVSHTSDMHRGYA | - | - | - | - | - | - | - | - | - | - | - |
S34 | MHRGYADSPSKAGAA | 6.9e-51 | - | 2.1e-19 | - | - | 1.2e-19 | 5.7e-9 | 6.9e-8 | 0.011 | 1.1e-11 | 0.29 |
S36 | RGYADSPSKAGAAPY | 0.024 | - | - | - | - | - | 0.024 | - | - | - | - |
S49 | PYVQAFDSLLAGPVA | -8.7e-3 | - | 0.96 | - | - | -1.7e-4 | - | - | - | - | - |
S91 | RALLVTASQCQQPAE | - | - | - | - | - | - | - | - | - | - | - |
S102 | QPAENKLSDLLAPIS | -0.56 | - | - | - | - | - | - | -0.56 | - | - | - |
S275 | THALKHVSDDMKTHK | 2.9e-7 | - | - | - | - | - | 0.29 | 2.5e-6 | - | 1.8e-4 | 0.45 |
S290 | NPALKAQSGPVRSGP | 1.1e-5 | - | - | - | - | - | - | - | - | 1.1e-5 | - |
S295 | AQSGPVRSGPKPFSA | 2.7e-14 | - | -0.073 | - | - | 8e-20 | 4.8e-3 | 3.8e-8 | - | 0.17 | - |
S301 | RSGPKPFSAPKPQTS | - | - | - | - | - | - | - | - | - | - | - |
Phenotype and mutation association
Signed p-values | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Phenotype | Site | Meta P | BRCA | CCRCC | COAD | GBM | HNSCC | LSCC | LUAD | OV | PDAC | UCEC |
No matching records found |
Cis-association
Kinase association
Signed p-values | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Kinase | Site | Meta P | BRCA | CCRCC | COAD | GBM | HNSCC | LSCC | LUAD | OV | PDAC | UCEC |
No matching records found |
Phosphatase association
Signed p-values | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Phosphatase | Site | Meta P | BRCA | CCRCC | COAD | GBM | HNSCC | LSCC | LUAD | OV | PDAC | UCEC |
No matching records found |