Protein: ENSP00000362110
Gene: SF3A3

LinkedOmicsKB © 2022-2023 Zhang Lab

SF3A3:
splicing factor 3a subunit 3

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Structure

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S292LFSTKGKSLESLDTS217------9-----------53
S295TKGKSLESLDTSLFA940923-883825--18104944554724732399
T298KSLESLDTSLFAKNP2169-43----------------
S365EEEEEQISESESEDE10876105-2522686662-4525837471636249207218
S367EEEQISESESEDEEN10899105-3026727162-4525836771636249208418
S369EQISESESEDEENEI1064039-3026727162-452520197163624920173
T475SERWQPDTEEEYEDS727358-----18-1610534898--2071214
Y479QPDTEEEYEDSSGNV188-------------------
Showing 1 to 8 of 8 rows

Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S292LFSTKGKSLESLDTS-----------
S295TKGKSLESLDTSLFA2.8e-37--5.7e-8--1.3e-232.9e-11---
T298KSLESLDTSLFAKNP-----------
S365EEEEEQISESESEDE2.6e-9--0.312.3e-5-0.226.1e-238.4e-8--0.016-0.13
S367EEEQISESESEDEEN7.2e-12--0.161.4e-5-0.114.4e-223.7e-8--0.0160.4
S369EQISESESEDEENEI1.9e-8--0.161.4e-5-0.0932.8e-91.8e-8--0.016-
T475SERWQPDTEEEYEDS0.075-----0.075----
Y479QPDTEEEYEDSSGNV-----------
Showing 1 to 8 of 8 rows

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAS292S295T298S365S367S369T475Y479proteinRNASCNVmethylationCCRCCS292S295T298S365S367S369T475Y479proteinRNASCNVmethylationCOADS292S295T298S365S367S369T475Y479proteinRNASCNVmethylationGBMS292S295T298S365S367S369T475Y479proteinRNASCNVmethylationHNSCCS292S295T298S365S367S369T475Y479proteinRNASCNVmethylationLSCCS292S295T298S365S367S369T475Y479proteinRNASCNVmethylationLUADS292S295T298S365S367S369T475Y479proteinRNASCNVmethylationOVS292S295T298S365S367S369T475Y479proteinRNASCNVmethylationPDACS292S295T298S365S367S369T475Y479proteinRNASCNVmethylationUCECS292S295T298S365S367S369T475Y479proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.