Protein: ENSP00000362424
Gene: TRAF3IP1

LinkedOmicsKB © 2022-2023 Zhang Lab

TRAF3IP1:
TRAF3 interacting protein 1

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Structure

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S146RASLTSRSQELDNKN3166----------20184945----259
S308KPEKKSASSGEMSKK17------------------7-
S317GEMSKKLSDGTFKDS5113------17---5444--84616
S333AETETEISTRASKSL387----------20191815----69
S425KQKGDSTSDAEGDAG2122----------54------9518
T444DKSEVPETPEIPNEL3109--54------2523------439
S463RRIPRPGSARPAPPR395----------19181815----169
S476PRVKRQDSMEALQMD71097--9572--99-1016010394110101--105449518
S557DYEKLQQSPKPGEKE7887--9876--64-3319108998880--92417712
Showing 1 to 9 of 9 rows

Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S146RASLTSRSQELDNKN-2.1e-15------1.9e-5-3.6e-12---
S308KPEKKSASSGEMSKK-----------
S317GEMSKKLSDGTFKDS-----------
S333AETETEISTRASKSL-0.69------0.69----
S425KQKGDSTSDAEGDAG2.4e-4---------2.4e-4
T444DKSEVPETPEIPNEL-0.54------0.54----
S463RRIPRPGSARPAPPR-----------
S476PRVKRQDSMEALQMD-2.5e-4--1.9e-6--0.018-0.024-0.18--4.7e-50.27
S557DYEKLQQSPKPGEKE1.8e-10-0.012---0.61.2e-91.4e-16--2.2e-66.2e-5
Showing 1 to 9 of 9 rows

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAS146S308S317S333S425T444S463S476S557proteinRNASCNVmethylationCCRCCS146S308S317S333S425T444S463S476S557proteinRNASCNVmethylationCOADS146S308S317S333S425T444S463S476S557proteinRNASCNVmethylationGBMS146S308S317S333S425T444S463S476S557proteinRNASCNVmethylationHNSCCS146S308S317S333S425T444S463S476S557proteinRNASCNVmethylationLSCCS146S308S317S333S425T444S463S476S557proteinRNASCNVmethylationLUADS146S308S317S333S425T444S463S476S557proteinRNASCNVmethylationOVS146S308S317S333S425T444S463S476S557proteinRNASCNVmethylationPDACS146S308S317S333S425T444S463S476S557proteinRNASCNVmethylationUCECS146S308S317S333S425T444S463S476S557proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.