Protein: ENSP00000362590
Gene: TBC1D22B

LinkedOmicsKB © 2022-2023 Zhang Lab

TBC1D22B:
TBC1 domain family member 22B

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Structure

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S58LKNKKASSFHEFARN101018105-4828252899-69399889898076172378216
S67HEFARNTSDAWDIGD848140-2524--44-412273676256--321111
S116VKPERSQSTTSDVPA6329----515682-63----44883626
T117KPERSQSTTSDVPAN81398-981620--72441717--1575-
T118PERSQSTTSDVPANY61279-2112--9-5215132120------
S119ERSQSTTSDVPANYK918418-885418-5219172120--32295
S132YKVIKSSSDAQLSRN1088021-44848691-523044396056561290389518
S137SSSDAQLSRNSSDTC249----------54--328----
S140DAQLSRNSSDTCLRN19----36--------------
S141AQLSRNSSDTCLRNP10131960-6950929699-91508476106977518105448918
Showing 1 to 10 of 11 rows
1025
rows per page

Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S58LKNKKASSFHEFARN1.2e-21-7.9e-30.016-3.0e-56.2e-53e-121.1e-6-0.85
S67HEFARNTSDAWDIGD0.051-1.6e-8---0.67-0.0160.28---
S116VKPERSQSTTSDVPA-0.02---0.02-------
T117KPERSQSTTSDVPAN-----------
T118PERSQSTTSDVPANY0.16-0.9----0.066---
S119ERSQSTTSDVPANYK0.066------0.066---
S132YKVIKSSSDAQLSRN7.6e-33--1.9e-4-1.2e-51.7e-75.3e-119.4e-32.7e-91.8e-3
S137SSSDAQLSRNSSDTC-----------
S140DAQLSRNSSDTCLRN-----------
S141AQLSRNSSDTCLRNP1e-19--1.5e-30.032-1.1e-47.5e-173.3e-222.2e-30.490.27
Showing 1 to 10 of 11 rows
1025
rows per page

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAS58S67S116T117T118S119S132S137S140S141S154proteinRNASCNVmethylationCCRCCS58S67S116T117T118S119S132S137S140S141S154proteinRNASCNVmethylationCOADS58S67S116T117T118S119S132S137S140S141S154proteinRNASCNVmethylationGBMS58S67S116T117T118S119S132S137S140S141S154proteinRNASCNVmethylationHNSCCS58S67S116T117T118S119S132S137S140S141S154proteinRNASCNVmethylationLSCCS58S67S116T117T118S119S132S137S140S141S154proteinRNASCNVmethylationLUADS58S67S116T117T118S119S132S137S140S141S154proteinRNASCNVmethylationOVS58S67S116T117T118S119S132S137S140S141S154proteinRNASCNVmethylationPDACS58S67S116T117T118S119S132S137S140S141S154proteinRNASCNVmethylationUCECS58S67S116T117T118S119S132S137S140S141S154proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.