GIGYF2: GRB10 interacting GYF protein 2
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
5nvl chain B
5nvl chain D
5nvm chain B
5nvm chain D
7rup chain A
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S19 PEWLRALS SGGSITS 4 119 - - - - - - 46 - - - - - 4 5 - - 9 5 35 15 S20 EWLRALSS GGSITSP 7 143 - - 12 12 - - 9 - 11 6 15 15 18 16 - - 13 6 10 - S23 RALSSGGS ITSPPLS 3 34 - - - - - - 18 - - - - - - - - - 5 1 10 - T25 LSSGGSIT SPPLSPA 6 187 - - 33 15 - - 9 - 7 3 24 23 30 28 - - - - 6 9 S26 SSGGSITS PPLSPAL 7 1125 - - 103 80 - - 99 - 108 62 108 99 106 98 - - 105 44 95 18 S30 SITSPPLS PALPKYK 7 1088 - - 95 72 - - 90 - 108 62 98 90 110 101 - - 105 44 95 18 S139 ECGFYQRS FDEVEGV 7 515 - - 28 17 - - 26 - 69 38 103 95 49 45 - - 3 2 24 16 S158 GGREMHRS QSWEERG 2 34 - - - - - - 17 - - - - - 9 8 - - - - - - S160 REMHRSQS WEERGDR 7 1123 - - 103 80 - - 99 - 108 62 108 99 105 97 - - 105 44 95 18 S189 FEEGGPTS VGRKHEF 5 41 - - 4 4 - - - - 5 4 5 4 - - - - 5 2 6 2
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S19 PEWLRALS SGGSITS -1.3e-4 - - - - - - - - - -1.3e-4 S20 EWLRALSS GGSITSP - - - - - - - - - - - S23 RALSSGGS ITSPPLS - - - - - - - - - - - T25 LSSGGSIT SPPLSPA 0.97 - 5.4e-4 - - - -0.012 -0.37 - - - S26 SSGGSITS PPLSPAL 0.081 - 2.2e-4 - - -1.0e-4 1.1e-7 2.9e-10 - -7.3e-11 -0.53 S30 SITSPPLS PALPKYK -2.3e-4 - 2.5e-8 - - -9.7e-10 -1.5e-4 0.45 - -1.9e-14 0.028 S139 ECGFYQRS FDEVEGV 8.1e-3 - 4.1e-4 - - 0.76 4.2e-4 1.4e-3 - - -3.5e-6 S158 GGREMHRS QSWEERG - - - - - - - - - - - S160 REMHRSQS WEERGDR 1.6e-10 - 2.2e-14 - - 4.2e-7 2.5e-11 3e-11 - -7.2e-14 -4.2e-3 S189 FEEGGPTS VGRKHEF - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S19
S20
S23
T25
S26
S30
S139
S158
S160
S189
S199
S201
S236
S242
S275
S277
S284
T299
S335
S337
S340
T373
S376
T382
S384
S417
S593
S650
S1001
S1091
S1100
S1104
S1108
S1275
S1280
S1284
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S19 S20 S23 T25 S26 S30 S139 S158 S160 S189 S199 S201 S236 S242 S275 S277 S284 T299 S335 S337 S340 T373 S376 T382 S384 S417 S593 S650 S1001 S1091 S1100 S1104 S1108 S1275 S1280 S1284 protein RNA SCNV methylation CCRCC S19 S20 S23 T25 S26 S30 S139 S158 S160 S189 S199 S201 S236 S242 S275 S277 S284 T299 S335 S337 S340 T373 S376 T382 S384 S417 S593 S650 S1001 S1091 S1100 S1104 S1108 S1275 S1280 S1284 protein RNA SCNV methylation COAD S19 S20 S23 T25 S26 S30 S139 S158 S160 S189 S199 S201 S236 S242 S275 S277 S284 T299 S335 S337 S340 T373 S376 T382 S384 S417 S593 S650 S1001 S1091 S1100 S1104 S1108 S1275 S1280 S1284 protein RNA SCNV methylation GBM S19 S20 S23 T25 S26 S30 S139 S158 S160 S189 S199 S201 S236 S242 S275 S277 S284 T299 S335 S337 S340 T373 S376 T382 S384 S417 S593 S650 S1001 S1091 S1100 S1104 S1108 S1275 S1280 S1284 protein RNA SCNV methylation HNSCC S19 S20 S23 T25 S26 S30 S139 S158 S160 S189 S199 S201 S236 S242 S275 S277 S284 T299 S335 S337 S340 T373 S376 T382 S384 S417 S593 S650 S1001 S1091 S1100 S1104 S1108 S1275 S1280 S1284 protein RNA SCNV methylation LSCC S19 S20 S23 T25 S26 S30 S139 S158 S160 S189 S199 S201 S236 S242 S275 S277 S284 T299 S335 S337 S340 T373 S376 T382 S384 S417 S593 S650 S1001 S1091 S1100 S1104 S1108 S1275 S1280 S1284 protein RNA SCNV methylation LUAD S19 S20 S23 T25 S26 S30 S139 S158 S160 S189 S199 S201 S236 S242 S275 S277 S284 T299 S335 S337 S340 T373 S376 T382 S384 S417 S593 S650 S1001 S1091 S1100 S1104 S1108 S1275 S1280 S1284 protein RNA SCNV methylation OV S19 S20 S23 T25 S26 S30 S139 S158 S160 S189 S199 S201 S236 S242 S275 S277 S284 T299 S335 S337 S340 T373 S376 T382 S384 S417 S593 S650 S1001 S1091 S1100 S1104 S1108 S1275 S1280 S1284 protein RNA SCNV methylation PDAC S19 S20 S23 T25 S26 S30 S139 S158 S160 S189 S199 S201 S236 S242 S275 S277 S284 T299 S335 S337 S340 T373 S376 T382 S384 S417 S593 S650 S1001 S1091 S1100 S1104 S1108 S1275 S1280 S1284 protein RNA SCNV methylation UCEC S19 S20 S23 T25 S26 S30 S139 S158 S160 S189 S199 S201 S236 S242 S275 S277 S284 T299 S335 S337 S340 T373 S376 T382 S384 S417 S593 S650 S1001 S1091 S1100 S1104 S1108 S1275 S1280 S1284 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S19
S20
S23
T25
S26
S30
S139
S158
S160
S189
S199
S201
S236
S242
S275
S277
S284
T299
S335
S337
S340
T373
S376
T382
S384
S417
S593
S650
S1001
S1091
S1100
S1104
S1108
S1275
S1280
S1284
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S19
S20
S23
T25
S26
S30
S139
S158
S160
S189
S199
S201
S236
S242
S275
S277
S284
T299
S335
S337
S340
T373
S376
T382
S384
S417
S593
S650
S1001
S1091
S1100
S1104
S1108
S1275
S1280
S1284
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.