Protein: ENSP00000362687
Gene: DDX50

LinkedOmicsKB © 2022-2023 Zhang Lab

DDX50:
DExD-box helicase 50

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Structure

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S35QKSDRRKSRHHYDSD125------------1312------
Y39RRKSRHHYDSDEKSE125------------1312------
S41KSRHHYDSDEKSETR10117768-3316848699-543310899110101195105449518
S45HYDSDEKSETRENGV8460--44221463-181038343732--6625849
T47DSDEKSETRENGVTD812017-4472--63232197--638-
T53ETRENGVTDDLDAPK6759-4436----181654--51--
S82EEGFNRLSDEFSKSH9854113-3230--44-643410395807240964273116
S112EKKSKRVSSLDTSTH126--------------215----
S113KKSKRVSSLDTSTHK7331--42----694120191085512601993
S117RVSSLDTSTHKSSDN245--------199----143----
Showing 1 to 10 of 21 rows
1025
rows per page

Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S35QKSDRRKSRHHYDSD-----------
Y39RRKSRHHYDSDEKSE-----------
S41KSRHHYDSDEKSETR2.1e-13-0.873.7e-23-0.984.6e-122.9e-12--5.2e-70.66
S45HYDSDEKSETRENGV0.017--1.4e-5--0.170.017--9.0e-4-
T47DSDEKSETRENGVTD0.086-----0.086----
T53ETRENGVTDDLDAPK-----------
S82EEGFNRLSDEFSKSH1.4e-31-0.77--6.7e-32.2e-323.1e-18-1.5e-30.057
S112EKKSKRVSSLDTSTH-----------
S113KKSKRVSSLDTSTHK0.72----1.2e-5-0.07-0.087-3.8e-4-
S117RVSSLDTSTHKSSDN-----------
Showing 1 to 10 of 21 rows
1025
rows per page

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAS35Y39S41S45T47T53S82S112S113S117T167Y172T183Y345T355S613S674S683S684S735proteinRNASCNVmethylationCCRCCS35Y39S41S45T47T53S82S112S113S117T167Y172T183Y345T355S613S674S683S684S735proteinRNASCNVmethylationCOADS35Y39S41S45T47T53S82S112S113S117T167Y172T183Y345T355S613S674S683S684S735proteinRNASCNVmethylationGBMS35Y39S41S45T47T53S82S112S113S117T167Y172T183Y345T355S613S674S683S684S735proteinRNASCNVmethylationHNSCCS35Y39S41S45T47T53S82S112S113S117T167Y172T183Y345T355S613S674S683S684S735proteinRNASCNVmethylationLSCCS35Y39S41S45T47T53S82S112S113S117T167Y172T183Y345T355S613S674S683S684S735proteinRNASCNVmethylationLUADS35Y39S41S45T47T53S82S112S113S117T167Y172T183Y345T355S613S674S683S684S735proteinRNASCNVmethylationOVS35Y39S41S45T47T53S82S112S113S117T167Y172T183Y345T355S613S674S683S684S735proteinRNASCNVmethylationPDACS35Y39S41S45T47T53S82S112S113S117T167Y172T183Y345T355S613S674S683S684S735proteinRNASCNVmethylationUCECS35Y39S41S45T47T53S82S112S113S117T167Y172T183Y345T355S613S674S683S684S735proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.