Protein: ENSP00000363071
Gene: DES

LinkedOmicsKB © 2022-2023 Zhang Lab

DES:
desmin

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T17RVSSYRRTFGGAPGF7489----8387--4726109454518825106115
S28APGFPLGSPLSSPVF101533122-103809710087-10862106991101018017105439518
S31FPLGSPLSSPVFPRA1046447-916851017-3925191839377193263
S32PLGSPLSSPVFPRAG107269-8890899-1046029332828361273326315
S42FPRAGFGSKGSSSSV4103----2735--73----20632--
S45AGFGSKGSSSSVTSR8723----87929-6484783736671584347218
S46GFGSKGSSSSVTSRV3112----2528----------156353
S47FGSKGSSSSVTSRVY5225----7875----10109862--27-
S48GSKGSSSSVTSRVYQ213----17----------41--
S51GSSSSVTSRVYQVSR2107----4643--135----------
Showing 1 to 10 of 43 rows
102550
rows per page

Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
T17RVSSYRRTFGGAPGF-4.6e-5---2.1e-13--0.12-0.47--0.48-0.8
S28APGFPLGSPLSSPVF-2.1e-67--4.1e-11-4e-23--0.01-2.1e-34-2.2e-32-2.2e-6-0.120.69
S31FPLGSPLSSPVFPRA-1.5e-22--2.3e-12---2.6e-4--3.8e-10---
S32PLGSPLSSPVFPRAG-1.1e-27---2.6e-20--0.074-5.8e-11-5.6e-11-3.0e-4-0.0840.53
S42FPRAGFGSKGSSSSV-1.5e-7---1.5e-7-------
S45AGFGSKGSSSSVTSR-5.6e-14---4.1e-10---7.4e-11-4.3e-4-3.8e-40.064-0.66
S46GFGSKGSSSSVTSRV-9.9e-8---9.9e-8-------
S47FGSKGSSSSVTSRVY-8.3e-14---8.3e-14-------
S48GSKGSSSSVTSRVYQ-----------
S51GSSSSVTSRVYQVSR-6.7e-10---6.7e-10-------
Showing 1 to 10 of 43 rows
102550
rows per page

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAT17S28S31S32S42S45S46S47S48S51S57T59S60S68S72T79S81S82Y83S92T149T219S231S266S290S298S301Y324S330Y331T332S344S358S361T422Y423S424T431S432S438T450T453S460proteinRNASCNVmethylationCCRCCT17S28S31S32S42S45S46S47S48S51S57T59S60S68S72T79S81S82Y83S92T149T219S231S266S290S298S301Y324S330Y331T332S344S358S361T422Y423S424T431S432S438T450T453S460proteinRNASCNVmethylationCOADT17S28S31S32S42S45S46S47S48S51S57T59S60S68S72T79S81S82Y83S92T149T219S231S266S290S298S301Y324S330Y331T332S344S358S361T422Y423S424T431S432S438T450T453S460proteinRNASCNVmethylationGBMT17S28S31S32S42S45S46S47S48S51S57T59S60S68S72T79S81S82Y83S92T149T219S231S266S290S298S301Y324S330Y331T332S344S358S361T422Y423S424T431S432S438T450T453S460proteinRNASCNVmethylationHNSCCT17S28S31S32S42S45S46S47S48S51S57T59S60S68S72T79S81S82Y83S92T149T219S231S266S290S298S301Y324S330Y331T332S344S358S361T422Y423S424T431S432S438T450T453S460proteinRNASCNVmethylationLSCCT17S28S31S32S42S45S46S47S48S51S57T59S60S68S72T79S81S82Y83S92T149T219S231S266S290S298S301Y324S330Y331T332S344S358S361T422Y423S424T431S432S438T450T453S460proteinRNASCNVmethylationLUADT17S28S31S32S42S45S46S47S48S51S57T59S60S68S72T79S81S82Y83S92T149T219S231S266S290S298S301Y324S330Y331T332S344S358S361T422Y423S424T431S432S438T450T453S460proteinRNASCNVmethylationOVT17S28S31S32S42S45S46S47S48S51S57T59S60S68S72T79S81S82Y83S92T149T219S231S266S290S298S301Y324S330Y331T332S344S358S361T422Y423S424T431S432S438T450T453S460proteinRNASCNVmethylationPDACT17S28S31S32S42S45S46S47S48S51S57T59S60S68S72T79S81S82Y83S92T149T219S231S266S290S298S301Y324S330Y331T332S344S358S361T422Y423S424T431S432S438T450T453S460proteinRNASCNVmethylationUCECT17S28S31S32S42S45S46S47S48S51S57T59S60S68S72T79S81S82Y83S92T149T219S231S266S290S298S301Y324S330Y331T332S344S358S361T422Y423S424T431S432S438T450T453S460proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.