Protein: ENSP00000363524
Gene: KIF4A

LinkedOmicsKB © 2022-2023 Zhang Lab

KIF4A:
kinesin family member 4A

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Structure

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S507TSPETSRSSDAFTTQ19--------------81----
S548RKMTQNDSQLQPIQY11313-------------------
T799PPKLRRRTFSLTEVR412131-------63----4010--274
S801KLRRRTFSLTEVRGQ972022---818081-69415444701592399518
S810TEVRGQVSESEDSIT123------------------194
S812VRGQVSESEDSITKQ16------------------6-
S815QVSESEDSITKQIES1064263-44736219-46318473292429621857
S894SLKQSKTSCADMQKM16------------------6-
S951AEKQLEESVSEKEQQ34718---45----1010--------
S953KQLEESVSEKEQQLL24334---63--------------
Showing 1 to 10 of 20 rows
1025
rows per page

Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S507TSPETSRSSDAFTTQ-----------
S548RKMTQNDSQLQPIQY-----------
T799PPKLRRRTFSLTEVR0.16-------0.16--
S801KLRRRTFSLTEVRGQ7.3e-16--9.6e-5-1.3e-7--0.182.5e-130.83
S810TEVRGQVSESEDSIT-----------
S812VRGQVSESEDSITKQ-----------
S815QVSESEDSITKQIES4.8e-54--6.9e-15-1.1e-103.5e-244.7e-11---
S894SLKQSKTSCADMQKM-----------
S951AEKQLEESVSEKEQQ-----------
S953KQLEESVSEKEQQLL-----------
Showing 1 to 10 of 20 rows
1025
rows per page

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAS507S548T799S801S810S812S815S894S951S953S961S1013S1016S1017Y1020S1048S1051S1126T1181S1186proteinRNASCNVmethylationCCRCCS507S548T799S801S810S812S815S894S951S953S961S1013S1016S1017Y1020S1048S1051S1126T1181S1186proteinRNASCNVmethylationCOADS507S548T799S801S810S812S815S894S951S953S961S1013S1016S1017Y1020S1048S1051S1126T1181S1186proteinRNASCNVmethylationGBMS507S548T799S801S810S812S815S894S951S953S961S1013S1016S1017Y1020S1048S1051S1126T1181S1186proteinRNASCNVmethylationHNSCCS507S548T799S801S810S812S815S894S951S953S961S1013S1016S1017Y1020S1048S1051S1126T1181S1186proteinRNASCNVmethylationLSCCS507S548T799S801S810S812S815S894S951S953S961S1013S1016S1017Y1020S1048S1051S1126T1181S1186proteinRNASCNVmethylationLUADS507S548T799S801S810S812S815S894S951S953S961S1013S1016S1017Y1020S1048S1051S1126T1181S1186proteinRNASCNVmethylationOVS507S548T799S801S810S812S815S894S951S953S961S1013S1016S1017Y1020S1048S1051S1126T1181S1186proteinRNASCNVmethylationPDACS507S548T799S801S810S812S815S894S951S953S961S1013S1016S1017Y1020S1048S1051S1126T1181S1186proteinRNASCNVmethylationUCECS507S548T799S801S810S812S815S894S951S953S961S1013S1016S1017Y1020S1048S1051S1126T1181S1186proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.