DAXX: death domain associated protein
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
2kqs chain B
2kzs chain A
2kzu chain A
4h9n chain C
4h9o chain C
4h9p chain C
4h9q chain C
4h9r chain C
4h9s chain E
4h9s chain F
4hga chain A
5grq chain A
5grq chain B
5kdm chain C
5y18 chain A
5y6o chain A
5y6o chain B
5y6o chain C
5y6o chain D
5y6o chain E
5y6o chain F
5y6o chain G
5y6o chain H
5y6o chain I
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S156 ATTSNEPS GNNPPTH 1 8 - - - - - - 8 - - - - - - - - - - - - - T169 THLSLDPT NAENTAS 1 9 - - - - 5 4 - - - - - - - - - - - - - - T174 DPTNAENT ASQSPRT 2 18 - - - - 5 4 - - - - - - 5 4 - - - - - - S178 AENTASQS PRTRGSR 4 200 - - - - 4 5 80 - - - - - - - 31 4 - - 58 18 S213 QEKELDLS ELDDPDS 9 561 63 - 17 16 - - 18 - 66 34 93 86 66 60 18 5 10 3 6 - Y259 VIEQRIPY RGTRYPE 1 18 - - - - 7 11 - - - - - - - - - - - - - - T262 QRIPYRGT RYPEVNR 1 18 - - - - 7 11 - - - - - - - - - - - - - - T401 RRARLQGT SSHSADT 4 41 6 - - - - - - - - - 4 4 5 4 - - - - 18 - S402 RARLQGTS SHSADTP 1 8 - - - - - - - - - - 4 4 - - - - - - - - S405 LQGTSSHS ADTPEAS 2 43 - - - - - - 26 - - - - - - - 14 3 - - - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S156 ATTSNEPS GNNPPTH - - - - - - - - - - - T169 THLSLDPT NAENTAS - - - - - - - - - - - T174 DPTNAENT ASQSPRT - - - - - - - - - - - S178 AENTASQS PRTRGSR 0.72 - - - - - - - - - 0.72 S213 QEKELDLS ELDDPDS 9.1e-8 - - - - -0.4 1.5e-8 9.7e-6 - - - Y259 VIEQRIPY RGTRYPE - - - - - - - - - - - T262 QRIPYRGT RYPEVNR - - - - - - - - - - - T401 RRARLQGT SSHSADT - - - - - - - - - - - S402 RARLQGTS SHSADTP - - - - - - - - - - - S405 LQGTSSHS ADTPEAS - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S156
T169
T174
S178
S213
Y259
T262
T401
S402
S405
T408
S412
S415
S495
S498
S499
S503
S518
T599
S609
T611
S618
S647
S654
T665
S668
S671
S675
S682
T684
S688
S690
T695
S702
T709
S737
S739
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S156 T169 T174 S178 S213 Y259 T262 T401 S402 S405 T408 S412 S415 S495 S498 S499 S503 S518 T599 S609 T611 S618 S647 S654 T665 S668 S671 S675 S682 T684 S688 S690 T695 S702 T709 S737 S739 protein RNA SCNV methylation CCRCC S156 T169 T174 S178 S213 Y259 T262 T401 S402 S405 T408 S412 S415 S495 S498 S499 S503 S518 T599 S609 T611 S618 S647 S654 T665 S668 S671 S675 S682 T684 S688 S690 T695 S702 T709 S737 S739 protein RNA SCNV methylation COAD S156 T169 T174 S178 S213 Y259 T262 T401 S402 S405 T408 S412 S415 S495 S498 S499 S503 S518 T599 S609 T611 S618 S647 S654 T665 S668 S671 S675 S682 T684 S688 S690 T695 S702 T709 S737 S739 protein RNA SCNV methylation GBM S156 T169 T174 S178 S213 Y259 T262 T401 S402 S405 T408 S412 S415 S495 S498 S499 S503 S518 T599 S609 T611 S618 S647 S654 T665 S668 S671 S675 S682 T684 S688 S690 T695 S702 T709 S737 S739 protein RNA SCNV methylation HNSCC S156 T169 T174 S178 S213 Y259 T262 T401 S402 S405 T408 S412 S415 S495 S498 S499 S503 S518 T599 S609 T611 S618 S647 S654 T665 S668 S671 S675 S682 T684 S688 S690 T695 S702 T709 S737 S739 protein RNA SCNV methylation LSCC S156 T169 T174 S178 S213 Y259 T262 T401 S402 S405 T408 S412 S415 S495 S498 S499 S503 S518 T599 S609 T611 S618 S647 S654 T665 S668 S671 S675 S682 T684 S688 S690 T695 S702 T709 S737 S739 protein RNA SCNV methylation LUAD S156 T169 T174 S178 S213 Y259 T262 T401 S402 S405 T408 S412 S415 S495 S498 S499 S503 S518 T599 S609 T611 S618 S647 S654 T665 S668 S671 S675 S682 T684 S688 S690 T695 S702 T709 S737 S739 protein RNA SCNV methylation OV S156 T169 T174 S178 S213 Y259 T262 T401 S402 S405 T408 S412 S415 S495 S498 S499 S503 S518 T599 S609 T611 S618 S647 S654 T665 S668 S671 S675 S682 T684 S688 S690 T695 S702 T709 S737 S739 protein RNA SCNV methylation PDAC S156 T169 T174 S178 S213 Y259 T262 T401 S402 S405 T408 S412 S415 S495 S498 S499 S503 S518 T599 S609 T611 S618 S647 S654 T665 S668 S671 S675 S682 T684 S688 S690 T695 S702 T709 S737 S739 protein RNA SCNV methylation UCEC S156 T169 T174 S178 S213 Y259 T262 T401 S402 S405 T408 S412 S415 S495 S498 S499 S503 S518 T599 S609 T611 S618 S647 S654 T665 S668 S671 S675 S682 T684 S688 S690 T695 S702 T709 S737 S739 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S156
T169
T174
S178
S213
Y259
T262
T401
S402
S405
T408
S412
S415
S495
S498
S499
S503
S518
T599
S609
T611
S618
S647
S654
T665
S668
S671
S675
S682
T684
S688
S690
T695
S702
T709
S737
S739
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S156
T169
T174
S178
S213
Y259
T262
T401
S402
S405
T408
S412
S415
S495
S498
S499
S503
S518
T599
S609
T611
S618
S647
S654
T665
S668
S671
S675
S682
T684
S688
S690
T695
S702
T709
S737
S739
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.