Protein: ENSP00000363787
Gene: RING1

LinkedOmicsKB © 2022-2023 Zhang Lab

RING1:
ring finger protein 1

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S38DGTEIAVSPRSLHSE101537122-10380939599-10862108991101018318101429518
S138LHNQQALSSSIEEGL46717-1716----5354--------
S139HNQQALSSSIEEGLR3268---45------45------
S140NQQALSSSIEEGLRM93269-1779982-63--181641101895418
T168PGSDQTTTMSGGEGE22417-----------------7-
S170SDQTTTMSGGEGEPG33117-------------7---7-
S187EGDGEDVSSDSAPDS73049-2422117----557569--136517
S188GDGEDVSSDSAPDSA834782-2422117--107537569--117122
S190GEDVSSDSAPDSAPG855182-2422117--452693777569--32132
S194SSDSAPDSAPGPAPK236--------169------83--
Showing 1 to 10 of 18 rows
1025
rows per page

Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S38DGTEIAVSPRSLHSE-5.6e-7-0.960.046--0.034-6.8e-7-0.33-0.091-3e-7-0.18
S138LHNQQALSSSIEEGL-----------
S139HNQQALSSSIEEGLR-----------
S140NQQALSSSIEEGLRM-0.044-------0.72--1.3e-3
T168PGSDQTTTMSGGEGE-----------
S170SDQTTTMSGGEGEPG-----------
S187EGDGEDVSSDSAPDS-0.76--1.2e-5----8.3e-5---
S188GDGEDVSSDSAPDSA-0.76--1.2e-5----8.3e-5---
S190GEDVSSDSAPDSAPG3.2e-8--1.2e-5--3.0e-52.4e-138.3e-5---
S194SSDSAPDSAPGPAPK-----------
Showing 1 to 10 of 18 rows
1025
rows per page

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAS38S138S139S140T168S170S187S188S190S194S211S212T215T220S229S232S248S254proteinRNASCNVmethylationCCRCCS38S138S139S140T168S170S187S188S190S194S211S212T215T220S229S232S248S254proteinRNASCNVmethylationCOADS38S138S139S140T168S170S187S188S190S194S211S212T215T220S229S232S248S254proteinRNASCNVmethylationGBMS38S138S139S140T168S170S187S188S190S194S211S212T215T220S229S232S248S254proteinRNASCNVmethylationHNSCCS38S138S139S140T168S170S187S188S190S194S211S212T215T220S229S232S248S254proteinRNASCNVmethylationLSCCS38S138S139S140T168S170S187S188S190S194S211S212T215T220S229S232S248S254proteinRNASCNVmethylationLUADS38S138S139S140T168S170S187S188S190S194S211S212T215T220S229S232S248S254proteinRNASCNVmethylationOVS38S138S139S140T168S170S187S188S190S194S211S212T215T220S229S232S248S254proteinRNASCNVmethylationPDACS38S138S139S140T168S170S187S188S190S194S211S212T215T220S229S232S248S254proteinRNASCNVmethylationUCECS38S138S139S140T168S170S187S188S190S194S211S212T215T220S229S232S248S254proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.