AGER: advanced glycosylation end-product specific receptor
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
2e5e chain A
2ens chain A
2l7u chain A
2le9 chain A
2le9 chain D
2lmb chain A
2m1k chain A
2m1k chain C
2mjw chain A
2mjw chain C
2mov chain A
3cjj chain A
3o3u chain N
4lp4 chain A
4lp4 chain B
4lp5 chain A
4lp5 chain B
4of5 chain A
4of5 chain B
4ofv chain A
4ofv chain B
4oi7 chain A
4oi7 chain B
4oi8 chain A
4oi8 chain B
4p2y chain A
4xyn chain P
4ybh chain A
5d7f chain P
6vxg chain A
6xq1 chain A
6xq1 chain B
6xq3 chain A
6xq3 chain B
6xq5 chain A
6xq5 chain B
6xq6 chain A
6xq6 chain B
6xq7 chain A
6xq7 chain B
6xq8 chain A
6xq8 chain B
6xq9 chain A
6xq9 chain B
7lml chain A
7lml chain B
7lmw chain A
7lmw chain B
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S65 TEAWKVLS PQGGGPW 1 8 - - - - - - - - - - - - 4 4 - - - - - - S74 QGGGPWDS VARVLPN 1 8 - - - - - - - - - - - - 4 4 - - - - - - S83 ARVLPNGS LFLPAVG 1 8 - - - - - - - - - - - - 4 4 - - - - - - S391 ERAELNQS EEPEAGE 2 194 - - - - - - - - - - 43 59 47 45 - - - - - - S399 EEPEAGES STGGP__ 3 218 - - - - - - - - 8 4 52 47 56 51 - - - - - - S400 EPEAGESS TGGP___ 3 207 - - - - - - - - 5 2 50 54 49 47 - - - - - - T401 PEAGESST GGP____ 2 42 - - - - - - - - - - 4 4 16 18 - - - - - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S65 TEAWKVLS PQGGGPW - - - - - - - - - - - S74 QGGGPWDS VARVLPN - - - - - - - - - - - S83 ARVLPNGS LFLPAVG - - - - - - - - - - - S391 ERAELNQS EEPEAGE -6.2e-33 - - - - - -8.7e-17 -9.1e-18 - - - S399 EEPEAGES STGGP__ -2.2e-31 - - - - - -2.1e-16 -1.4e-16 - - - S400 EPEAGESS TGGP___ -1.1e-34 - - - - - -3.6e-15 -2.1e-21 - - - T401 PEAGESST GGP____ - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S65
S74
S83
S391
S399
S400
T401
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S65 S74 S83 S391 S399 S400 T401 protein RNA SCNV methylation CCRCC S65 S74 S83 S391 S399 S400 T401 protein RNA SCNV methylation COAD S65 S74 S83 S391 S399 S400 T401 protein RNA SCNV methylation GBM S65 S74 S83 S391 S399 S400 T401 protein RNA SCNV methylation HNSCC S65 S74 S83 S391 S399 S400 T401 protein RNA SCNV methylation LSCC S65 S74 S83 S391 S399 S400 T401 protein RNA SCNV methylation LUAD S65 S74 S83 S391 S399 S400 T401 protein RNA SCNV methylation OV S65 S74 S83 S391 S399 S400 T401 protein RNA SCNV methylation PDAC S65 S74 S83 S391 S399 S400 T401 protein RNA SCNV methylation UCEC S65 S74 S83 S391 S399 S400 T401 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S65
S74
S83
S391
S399
S400
T401
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S65
S74
S83
S391
S399
S400
T401
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.