Protein: ENSP00000364578
Gene: NELFE

LinkedOmicsKB © 2022-2023 Zhang Lab

NELFE:
negative elongation factor complex member E

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Structure

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S36LLALKKQSSSSTTSQ19------9-------------
S37LALKKQSSSSTTSQG839621-----90-19920194436670335015
S38ALKKQSSSSTTSQGG6180------27-2716982220--165282
S39LKKQSSSSTTSQGGV3319---------55------102
S42QSSSSTTSQGGVKRS114------------------113
S49SQGGVKRSLSEQPVM845356-2315282627-10749454137----7118
S51GGVKRSLSEQPVMDT101512122-98769710099-104581089997908319105449518
T58SEQPVMDTATATEQA188-------------------
T91SGFKRSRTLEGKLKD101410105-7966868490-108621039497896916105449518
S113TFQPFQRSISADDDL62576-----35---15148477143--72
Showing 1 to 10 of 28 rows
102550
rows per page

Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S36LLALKKQSSSSTTSQ-----------
S37LALKKQSSSSTTSQG-2.3e-8------0.25---4.7e-6-7.9e-5
S38ALKKQSSSSTTSQGG0.43-----0.064-2.9e-3---
S39LKKQSSSSTTSQGGV-----------
S42QSSSSTTSQGGVKRS-----------
S49SQGGVKRSLSEQPVM3.8e-3-0.0220.86---0.0316.1e-5--0.032
S51GGVKRSLSEQPVMDT1.0e-5-7.2e-43.5e-4-0.418.4e-52.7e-13-0.012-0.025-0.074
T58SEQPVMDTATATEQA-----------
T91SGFKRSRTLEGKLKD0.075-1.1e-81.1e-3--0.28-0.886.7e-60.014-4e-12-6.3e-3
S113TFQPFQRSISADDDL1.6e-14------1.6e-14---
Showing 1 to 10 of 28 rows
102550
rows per page

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAS36S37S38S39S42S49S51T58T91S113S115S123S124S131S135S138S139S165S174S178S179S181S185S251T272S281S353S368proteinRNASCNVmethylationCCRCCS36S37S38S39S42S49S51T58T91S113S115S123S124S131S135S138S139S165S174S178S179S181S185S251T272S281S353S368proteinRNASCNVmethylationCOADS36S37S38S39S42S49S51T58T91S113S115S123S124S131S135S138S139S165S174S178S179S181S185S251T272S281S353S368proteinRNASCNVmethylationGBMS36S37S38S39S42S49S51T58T91S113S115S123S124S131S135S138S139S165S174S178S179S181S185S251T272S281S353S368proteinRNASCNVmethylationHNSCCS36S37S38S39S42S49S51T58T91S113S115S123S124S131S135S138S139S165S174S178S179S181S185S251T272S281S353S368proteinRNASCNVmethylationLSCCS36S37S38S39S42S49S51T58T91S113S115S123S124S131S135S138S139S165S174S178S179S181S185S251T272S281S353S368proteinRNASCNVmethylationLUADS36S37S38S39S42S49S51T58T91S113S115S123S124S131S135S138S139S165S174S178S179S181S185S251T272S281S353S368proteinRNASCNVmethylationOVS36S37S38S39S42S49S51T58T91S113S115S123S124S131S135S138S139S165S174S178S179S181S185S251T272S281S353S368proteinRNASCNVmethylationPDACS36S37S38S39S42S49S51T58T91S113S115S123S124S131S135S138S139S165S174S178S179S181S185S251T272S281S353S368proteinRNASCNVmethylationUCECS36S37S38S39S42S49S51T58T91S113S115S123S124S131S135S138S139S165S174S178S179S181S185S251T272S281S353S368proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.