CROCC: ciliary rootlet coiled-coil, rootletin
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
6l5h chain A
6l5h chain B
6l5j chain A
6l5j chain B
6l5j chain C
6l5j chain D
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T45 LAQDAQIT SLPALIR 1 7 - - - - - - - - 5 2 - - - - - - - - - - S46 AQDAQITS LPALIRE 1 7 - - - - - - - - 5 2 - - - - - - - - - - S141 PRGLVRQS VELRRQL 1 16 - - - - - - - - - - - - 8 8 - - - - - - S462 DLAQAVLS DSESGVQ 10 921 72 - 26 23 9 9 81 - 86 48 96 89 86 80 17 6 61 27 87 18 S464 AQAVLSDS ESGVQLS 6 110 30 - - - - - 9 - - - 20 18 9 8 - - 3 2 11 - S466 AVLSDSES GVQLSGS 3 39 9 - - - - - 9 - - - - - - - - - - - 12 9 S471 SESGVQLS GSERTAD 2 53 - - - - - - - - - - 13 13 - - - - - - 18 9 S473 SGVQLSGS ERTADAS 2 24 - - - - - - - - - - 5 4 - - - - - - 6 9 S480 SERTADAS NGSLRGL 5 184 17 - - - - - 18 - - - 40 35 35 32 - - - - 5 2 S483 TADASNGS LRGLSGQ 10 1005 91 - 75 55 25 20 19 - 72 43 103 94 91 84 22 3 105 44 50 9
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
T45 LAQDAQIT SLPALIR - - - - - - - - - - - S46 AQDAQITS LPALIRE - - - - - - - - - - - S141 PRGLVRQS VELRRQL - - - - - - - - - - - S462 DLAQAVLS DSESGVQ -2.4e-26 - -0.49 - - -2.5e-5 -2.9e-15 -2.6e-14 - -3.4e-3 -7.5e-3 S464 AQAVLSDS ESGVQLS -0.61 - - - - - -0.61 - - - - S466 AVLSDSES GVQLSGS - - - - - - - - - - - S471 SESGVQLS GSERTAD - - - - - - - - - - - S473 SGVQLSGS ERTADAS - - - - - - - - - - - S480 SERTADAS NGSLRGL 7e-7 - - - - - 1.2e-8 0.19 - - - S483 TADASNGS LRGLSGQ 1.7e-4 - 1.8e-11 2.5e-3 - 0.82 1.5e-15 -1.5e-7 - -4.9e-4 -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
T45
S46
S141
S462
S464
S466
S471
S473
S480
S483
T492
S494
S499
S500
S506
S512
S516
S518
S519
S606
S807
S830
S844
S1065
S1204
S1218
S1369
S1451
S1460
S1470
S1478
T1479
S1483
S1486
S1490
T1495
S1496
S1499
S1569
S1575
T1598
S1619
S1660
S1741
T1832
T1881
S1892
S1900
T1911
S1937
S1939
S1963
S2004
S2005
S2009
S2012
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA T45 S46 S141 S462 S464 S466 S471 S473 S480 S483 T492 S494 S499 S500 S506 S512 S516 S518 S519 S606 S807 S830 S844 S1065 S1204 S1218 S1369 S1451 S1460 S1470 S1478 T1479 S1483 S1486 S1490 T1495 S1496 S1499 S1569 S1575 T1598 S1619 S1660 S1741 T1832 T1881 S1892 S1900 T1911 S1937 S1939 S1963 S2004 S2005 S2009 S2012 protein RNA SCNV methylation CCRCC T45 S46 S141 S462 S464 S466 S471 S473 S480 S483 T492 S494 S499 S500 S506 S512 S516 S518 S519 S606 S807 S830 S844 S1065 S1204 S1218 S1369 S1451 S1460 S1470 S1478 T1479 S1483 S1486 S1490 T1495 S1496 S1499 S1569 S1575 T1598 S1619 S1660 S1741 T1832 T1881 S1892 S1900 T1911 S1937 S1939 S1963 S2004 S2005 S2009 S2012 protein RNA SCNV methylation COAD T45 S46 S141 S462 S464 S466 S471 S473 S480 S483 T492 S494 S499 S500 S506 S512 S516 S518 S519 S606 S807 S830 S844 S1065 S1204 S1218 S1369 S1451 S1460 S1470 S1478 T1479 S1483 S1486 S1490 T1495 S1496 S1499 S1569 S1575 T1598 S1619 S1660 S1741 T1832 T1881 S1892 S1900 T1911 S1937 S1939 S1963 S2004 S2005 S2009 S2012 protein RNA SCNV methylation GBM T45 S46 S141 S462 S464 S466 S471 S473 S480 S483 T492 S494 S499 S500 S506 S512 S516 S518 S519 S606 S807 S830 S844 S1065 S1204 S1218 S1369 S1451 S1460 S1470 S1478 T1479 S1483 S1486 S1490 T1495 S1496 S1499 S1569 S1575 T1598 S1619 S1660 S1741 T1832 T1881 S1892 S1900 T1911 S1937 S1939 S1963 S2004 S2005 S2009 S2012 protein RNA SCNV methylation HNSCC T45 S46 S141 S462 S464 S466 S471 S473 S480 S483 T492 S494 S499 S500 S506 S512 S516 S518 S519 S606 S807 S830 S844 S1065 S1204 S1218 S1369 S1451 S1460 S1470 S1478 T1479 S1483 S1486 S1490 T1495 S1496 S1499 S1569 S1575 T1598 S1619 S1660 S1741 T1832 T1881 S1892 S1900 T1911 S1937 S1939 S1963 S2004 S2005 S2009 S2012 protein RNA SCNV methylation LSCC T45 S46 S141 S462 S464 S466 S471 S473 S480 S483 T492 S494 S499 S500 S506 S512 S516 S518 S519 S606 S807 S830 S844 S1065 S1204 S1218 S1369 S1451 S1460 S1470 S1478 T1479 S1483 S1486 S1490 T1495 S1496 S1499 S1569 S1575 T1598 S1619 S1660 S1741 T1832 T1881 S1892 S1900 T1911 S1937 S1939 S1963 S2004 S2005 S2009 S2012 protein RNA SCNV methylation LUAD T45 S46 S141 S462 S464 S466 S471 S473 S480 S483 T492 S494 S499 S500 S506 S512 S516 S518 S519 S606 S807 S830 S844 S1065 S1204 S1218 S1369 S1451 S1460 S1470 S1478 T1479 S1483 S1486 S1490 T1495 S1496 S1499 S1569 S1575 T1598 S1619 S1660 S1741 T1832 T1881 S1892 S1900 T1911 S1937 S1939 S1963 S2004 S2005 S2009 S2012 protein RNA SCNV methylation OV T45 S46 S141 S462 S464 S466 S471 S473 S480 S483 T492 S494 S499 S500 S506 S512 S516 S518 S519 S606 S807 S830 S844 S1065 S1204 S1218 S1369 S1451 S1460 S1470 S1478 T1479 S1483 S1486 S1490 T1495 S1496 S1499 S1569 S1575 T1598 S1619 S1660 S1741 T1832 T1881 S1892 S1900 T1911 S1937 S1939 S1963 S2004 S2005 S2009 S2012 protein RNA SCNV methylation PDAC T45 S46 S141 S462 S464 S466 S471 S473 S480 S483 T492 S494 S499 S500 S506 S512 S516 S518 S519 S606 S807 S830 S844 S1065 S1204 S1218 S1369 S1451 S1460 S1470 S1478 T1479 S1483 S1486 S1490 T1495 S1496 S1499 S1569 S1575 T1598 S1619 S1660 S1741 T1832 T1881 S1892 S1900 T1911 S1937 S1939 S1963 S2004 S2005 S2009 S2012 protein RNA SCNV methylation UCEC T45 S46 S141 S462 S464 S466 S471 S473 S480 S483 T492 S494 S499 S500 S506 S512 S516 S518 S519 S606 S807 S830 S844 S1065 S1204 S1218 S1369 S1451 S1460 S1470 S1478 T1479 S1483 S1486 S1490 T1495 S1496 S1499 S1569 S1575 T1598 S1619 S1660 S1741 T1832 T1881 S1892 S1900 T1911 S1937 S1939 S1963 S2004 S2005 S2009 S2012 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
Loading, please wait
all sites
T45
S46
S141
S462
S464
S466
S471
S473
S480
S483
T492
S494
S499
S500
S506
S512
S516
S518
S519
S606
S807
S830
S844
S1065
S1204
S1218
S1369
S1451
S1460
S1470
S1478
T1479
S1483
S1486
S1490
T1495
S1496
S1499
S1569
S1575
T1598
S1619
S1660
S1741
T1832
T1881
S1892
S1900
T1911
S1937
S1939
S1963
S2004
S2005
S2009
S2012
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
Loading, please wait
all sites
T45
S46
S141
S462
S464
S466
S471
S473
S480
S483
T492
S494
S499
S500
S506
S512
S516
S518
S519
S606
S807
S830
S844
S1065
S1204
S1218
S1369
S1451
S1460
S1470
S1478
T1479
S1483
S1486
S1490
T1495
S1496
S1499
S1569
S1575
T1598
S1619
S1660
S1741
T1832
T1881
S1892
S1900
T1911
S1937
S1939
S1963
S2004
S2005
S2009
S2012
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.