MAPRE1: microtubule associated protein RP/EB family member 1
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
1pa7 chain A
1txq chain B
1ueg chain A
1vka chain A
1vka chain B
1wu9 chain A
1wu9 chain B
1yib chain A
1yig chain A
1yig chain B
2hkq chain A
2hl3 chain C
2hl5 chain A
2hl5 chain B
2qjz chain A
2qjz chain B
2r8u chain A
2r8u chain B
3gjo chain A
3gjo chain B
3gjo chain C
3gjo chain D
3mtu chain A
3mtu chain B
3mtu chain C
3mtu chain D
3mud chain C
3mud chain D
3tq7 chain A
4xa1 chain A
4xa1 chain B
4xa1 chain C
4xa1 chain D
4xa3 chain A
4xa3 chain B
4xa6 chain A
4xa6 chain B
4xa6 chain C
4xa6 chain D
5jv3 chain A
5jv3 chain B
5jv3 chain C
5jv3 chain D
5jvm chain A
5jvm chain B
5jvp chain A
5jvp chain B
5jvp chain C
5jvp chain D
5jvp chain E
5jvp chain F
5jvr chain A
5jvr chain B
5jvr chain C
5jvr chain D
5jvr chain E
5jvr chain F
5jvr chain G
5jvr chain H
5jvs chain A
5jvu chain A
5jvu chain B
5jx1 chain A
6pf2 chain A
6pf2 chain B
6pfp chain A
6pfp chain B
6pfp chain C
6pfp chain D
6yf5 chain A
6yf5 chain B
6yf5 chain C
6yf5 chain D
6ysh chain A
6ysh chain B
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
Loading, please wait
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S55 MDMLFPGS IALKKVK 1 8 - - 4 4 - - - - - - - - - - - - - - - - T154 NKPKKPLT SSSAAPQ 2 51 - - - - - - 9 - - - - - - - - - 30 12 - - S155 KPKKPLTS SSAAPQR 10 1369 116 - 57 44 97 100 99 - 108 62 108 99 93 85 41 10 97 40 95 18 S156 PKKPLTSS SAAPQRP 3 36 - - - - 4 5 18 - 5 4 - - - - - - - - - - S165 AAPQRPIS TQRTAAA 10 1273 96 - 99 76 86 84 99 - 97 56 88 79 110 100 7 2 65 28 83 18
Tumor and normal comparison
Loading, please wait
Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S55 MDMLFPGS IALKKVK - - - - - - - - - - - T154 NKPKKPLT SSSAAPQ 0.5 - - - - - - - - 0.5 - S155 KPKKPLTS SSAAPQR 5.3e-14 - 3.5e-4 0.99 - 1e-13 3.2e-12 -1.0e-5 0.65 1.9e-7 0.04 S156 PKKPLTSS SAAPQRP - - - - - - - - - - - S165 AAPQRPIS TQRTAAA 1.5e-8 - 3.2e-22 -2.5e-6 - 3.8e-11 -0.91 -0.13 - 3.8e-3 0.034
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
Loading, please wait
all sites
S55
T154
S155
S156
S165
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S55 T154 S155 S156 S165 protein RNA SCNV methylation CCRCC S55 T154 S155 S156 S165 protein RNA SCNV methylation COAD S55 T154 S155 S156 S165 protein RNA SCNV methylation GBM S55 T154 S155 S156 S165 protein RNA SCNV methylation HNSCC S55 T154 S155 S156 S165 protein RNA SCNV methylation LSCC S55 T154 S155 S156 S165 protein RNA SCNV methylation LUAD S55 T154 S155 S156 S165 protein RNA SCNV methylation OV S55 T154 S155 S156 S165 protein RNA SCNV methylation PDAC S55 T154 S155 S156 S165 protein RNA SCNV methylation UCEC S55 T154 S155 S156 S165 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
Loading, please wait
all sites
S55
T154
S155
S156
S165
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
Loading, please wait
all sites
S55
T154
S155
S156
S165
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.