Protein: ENSP00000364912

SPEN:: spen family transcriptional repressor

Lollipop plot

Phosphosites location and occurrence

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* Hover over the dots to see sequence motif and cohorts.

Structure

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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				BRCA		CCRCC		COAD		GBM		HNSCC		LSCC		LUAD		OV		PDAC		UCEC
Site	Sequence	Cohorts	Total	T	N	T	N	T	N	T	N	T	N	T	N	T	N	T	N	T	N	T	N
S43	KILPKRGSEGGVAAF	2	86	21	-	-	-	-	-	-	-	-	-	34	31	-	-	-	-	-	-	-	-
S188	GLYYASRSRSPNRFD	2	36	-	-	-	-	10	16	-	-	-	-	-	-	-	-	-	-	7	3	-	-
S190	YYASRSRSPNRFDAH	10	1363	105	-	95	72	97	100	99	-	85	48	108	99	101	93	68	13	63	28	71	18
S240	PERNYQHSRSRSPHS	6	408	26	-	-	-	-	-	73	-	43	22	55	53	48	44	-	-	-	-	28	16
S242	RNYQHSRSRSPHSSQ	6	416	26	-	-	-	-	-	81	-	43	22	55	53	48	44	-	-	-	-	28	16
S244	YQHSRSRSPHSSQSR	7	457	26	-	-	-	-	-	81	-	43	22	55	53	48	44	37	4	-	-	28	16
S248	RSRSPHSSQSRNQSP	1	4	-	-	-	-	-	-	-	-	-	-	-	-	-	-	4	-	-	-	-	-
T266	ASQASRPTRSPSGSG	1	9	9	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
S268	QASRPTRSPSGSGSR	2	54	-	-	4	3	-	-	-	-	-	-	25	22	-	-	-	-	-	-	-	-
S270	SRPTRSPSGSGSRSR	1	7	-	-	4	3	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-

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Tumor and normal comparison

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Site	Sequence	Meta P	BRCA	CCRCC	COAD	GBM	HNSCC	LSCC	LUAD	OV	PDAC	UCEC
S43	KILPKRGSEGGVAAF	0.063	-	-	-	-	-	0.063	-	-	-	-
S188	GLYYASRSRSPNRFD	-	-	-	-	-	-	-	-	-	-	-
S190	YYASRSRSPNRFDAH	9.2e-30	-	-4.8e-5	6.4e-23	-	8.3e-12	1.3e-30	4.1e-24	1.4e-3	-1.0e-4	-0.13
S240	PERNYQHSRSRSPHS	6.6e-11	-	-	-	-	0.045	3.5e-3	1.9e-9	-	-	0.034
S242	RNYQHSRSRSPHSSQ	6.6e-11	-	-	-	-	0.045	3.5e-3	1.9e-9	-	-	0.034
S244	YQHSRSRSPHSSQSR	6.6e-11	-	-	-	-	0.045	3.5e-3	1.9e-9	-	-	0.034
S248	RSRSPHSSQSRNQSP	-	-	-	-	-	-	-	-	-	-	-
T266	ASQASRPTRSPSGSG	-	-	-	-	-	-	-	-	-	-	-
S268	QASRPTRSPSGSGSR	7.7e-6	-	-	-	-	-	7.7e-6	-	-	-	-
S270	SRPTRSPSGSGSRSR	-	-	-	-	-	-	-	-	-	-	-

Showing 1 to 10 of 118 rows

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* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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			Signed p-values
Phenotype	Site	Meta P	BRCA	CCRCC	COAD	GBM	HNSCC	LSCC	LUAD	OV	PDAC	UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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			Signed p-values
Kinase	Site	Meta P	BRCA	CCRCC	COAD	GBM	HNSCC	LSCC	LUAD	OV	PDAC	UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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			Signed p-values
Phosphatase	Site	Meta P	BRCA	CCRCC	COAD	GBM	HNSCC	LSCC	LUAD	OV	PDAC	UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Protein: ENSP00000364912Gene: SPEN

Lollipop plot

Structure

Phosphosite detection coverage

Tumor and normal comparison

Phenotype and mutation association

Cis-association

Kinase association

Phosphatase association

Protein: ENSP00000364912
Gene: SPEN