Protein: ENSP00000365312
Gene: ABI1

LinkedOmicsKB © 2022-2023 Zhang Lab

ABI1:
abl interactor 1

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Structure

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S183PPTQKPPSPPMSGRG71132--10380--99-1086210899110101--105449518
S187KPPSPPMSGRGTLGR6172--1615--27-2819151499--137--
T191PPMSGRGTLGRNTPY7108--124--19-98151454--41112
T196RGTLGRNTPYKTLEP7351--2112--35-473253483229--20814-
T200GRNTPYKTLEPVKPP7612--1311--99-804625243533--100418718
T208LEPVKPPTVPNDYMT15----------------41--
Y213PPTVPNDYMTSPARL7443--2120--46-875060541816--239363
T215TVPNDYMTSPARLGS6172--2514--18-16925221815--73--
S216VPNDYMTSPARLGSQ7440--88--44-764420192924--50198316
S222TSPARLGSQHSPGRT7697--3736--90-975633315044--78329518
Showing 1 to 10 of 27 rows
102550
rows per page

Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S183PPTQKPPSPPMSGRG2.3e-6--7.7e-13---0.0743.7e-170.14-1e-111.2e-4
S187KPPSPPMSGRGTLGR-2.1e-3-----2.1e-3-----
T191PPMSGRGTLGRNTPY-----------
T196RGTLGRNTPYKTLEP6.7e-8-0.24--0.759.2e-87.4e-5---
T200GRNTPYKTLEPVKPP-3.1e-4-----6.0e-4-1.6e-3-1.2e-6-1.1e-10-2.1e-3
T208LEPVKPPTVPNDYMT-----------
Y213PPTVPNDYMTSPARL-1.6e-10-9.1e-3---5.7e-12-1.1e-11----
T215TVPNDYMTSPARLGS9.6e-6-0.026---5.6e-5----
S216VPNDYMTSPARLGSQ5.1e-4-----0.0122.3e-40.23-3.6e-50.21
S222TSPARLGSQHSPGRT1.1e-3--0.084--0.13-0.920.036-1.3e-90.87
Showing 1 to 10 of 27 rows
102550
rows per page

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAS183S187T191T196T200T208Y213T215S216S222S225T229S231T238S240S242S243S319S323T324T325S326S327T328S329Y484T507proteinRNASCNVmethylationCCRCCS183S187T191T196T200T208Y213T215S216S222S225T229S231T238S240S242S243S319S323T324T325S326S327T328S329Y484T507proteinRNASCNVmethylationCOADS183S187T191T196T200T208Y213T215S216S222S225T229S231T238S240S242S243S319S323T324T325S326S327T328S329Y484T507proteinRNASCNVmethylationGBMS183S187T191T196T200T208Y213T215S216S222S225T229S231T238S240S242S243S319S323T324T325S326S327T328S329Y484T507proteinRNASCNVmethylationHNSCCS183S187T191T196T200T208Y213T215S216S222S225T229S231T238S240S242S243S319S323T324T325S326S327T328S329Y484T507proteinRNASCNVmethylationLSCCS183S187T191T196T200T208Y213T215S216S222S225T229S231T238S240S242S243S319S323T324T325S326S327T328S329Y484T507proteinRNASCNVmethylationLUADS183S187T191T196T200T208Y213T215S216S222S225T229S231T238S240S242S243S319S323T324T325S326S327T328S329Y484T507proteinRNASCNVmethylationOVS183S187T191T196T200T208Y213T215S216S222S225T229S231T238S240S242S243S319S323T324T325S326S327T328S329Y484T507proteinRNASCNVmethylationPDACS183S187T191T196T200T208Y213T215S216S222S225T229S231T238S240S242S243S319S323T324T325S326S327T328S329Y484T507proteinRNASCNVmethylationUCECS183S187T191T196T200T208Y213T215S216S222S225T229S231T238S240S242S243S319S323T324T325S326S327T328S329Y484T507proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.