Protein: ENSP00000365682
Gene: TLE1

LinkedOmicsKB © 2022-2023 Zhang Lab

TLE1:
TLE family member 1, transcriptional corepressor

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Structure

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S201REPGTSNSLLVPDSL118------------------162
S234RKVDDKDSSHYDSDG226------------54----125
S235KVDDKDSSHYDSDGD217------------54----53
Y237DDKDSSHYDSDGDKS223------------54----113
S239KDSSHYDSDGDKSDD86866-----99-82479386322727748199518
S244YDSDGDKSDDNLVVD35316-----18-----------172
S258DVSNEDPSSPRASPA3168--3231--18-----------6918
S259VSNEDPSSPRASPAH41949-3231--27-----------7916
S263DPSSPRASPAHSPRE838832-4039--54---302714125313644816
S267PRASPAHSPRENGID9606105-1212--90-117393750437213648718
Showing 1 to 10 of 19 rows
1025
rows per page

Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S201REPGTSNSLLVPDSL-----------
S234RKVDDKDSSHYDSDG-----------
S235KVDDKDSSHYDSDGD-----------
Y237DDKDSSHYDSDGDKS-----------
S239KDSSHYDSDGDKSDD6.7e-5-----0.361.4e-62.6e-7--3.3e-45.6e-4
S244YDSDGDKSDDNLVVD-----------
S258DVSNEDPSSPRASPA0.78-0.86-------0.82
S259VSNEDPSSPRASPAH0.66-0.86-------0.66
S263DPSSPRASPAHSPRE2.1e-7-1---4.9e-3-2.4e-4-0.012
S267PRASPAHSPRENGID2.8e-7-----1.5e-44.7e-50.051-0.64
Showing 1 to 10 of 19 rows
1025
rows per page

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAS201S234S235Y237S239S244S258S259S263S267S286S293S295S296S298S305T312T319T328proteinRNASCNVmethylationCCRCCS201S234S235Y237S239S244S258S259S263S267S286S293S295S296S298S305T312T319T328proteinRNASCNVmethylationCOADS201S234S235Y237S239S244S258S259S263S267S286S293S295S296S298S305T312T319T328proteinRNASCNVmethylationGBMS201S234S235Y237S239S244S258S259S263S267S286S293S295S296S298S305T312T319T328proteinRNASCNVmethylationHNSCCS201S234S235Y237S239S244S258S259S263S267S286S293S295S296S298S305T312T319T328proteinRNASCNVmethylationLSCCS201S234S235Y237S239S244S258S259S263S267S286S293S295S296S298S305T312T319T328proteinRNASCNVmethylationLUADS201S234S235Y237S239S244S258S259S263S267S286S293S295S296S298S305T312T319T328proteinRNASCNVmethylationOVS201S234S235Y237S239S244S258S259S263S267S286S293S295S296S298S305T312T319T328proteinRNASCNVmethylationPDACS201S234S235Y237S239S244S258S259S263S267S286S293S295S296S298S305T312T319T328proteinRNASCNVmethylationUCECS201S234S235Y237S239S244S258S259S263S267S286S293S295S296S298S305T312T319T328proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.