MYH14: myosin heavy chain 14
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
5i4e chain A
5jlh chain F
5jlh chain G
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T30 AAQPFLFT PRGPSAG 7 415 - - 4 3 14 13 - - 19 9 34 31 83 76 - - 45 15 62 7 S35 LFTPRGPS AGGGPGS 2 19 - - - - - - - - - - 5 5 - - - - - - 7 2 S42 SAGGGPGS GTSPQVE 2 33 - - - - - - - - - - 10 10 - - - - - - 13 - S45 GGPGSGTS PQVEWTA 9 882 73 - - - 64 53 26 - 81 47 93 85 76 68 35 7 47 22 87 18 S85 AEVELAES GRRLRLP 1 10 - - - - - - - - - - 5 5 - - - - - - - - S220 QYLAHVAS SPKGRKE 3 51 33 - - - - - - - - - 5 5 4 4 - - - - - - S221 YLAHVASS PKGRKEP 4 250 - - - - 77 75 - - 29 18 - - - - - - 13 3 30 5 S337 LTNGPSSS PGQEREL 1 8 - - - - - - - - - - - - - - - - - - 6 2 S358 SLRVLGFS HEEIISM 1 9 - - - - - - - - - - - - - - 8 1 - - - - T390 ERNTDQAT MPDNTAA 1 9 - - - - 3 6 - - - - - - - - - - - - - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
T30 AAQPFLFT PRGPSAG -0.44 - - - - - -0.16 -3.1e-3 - 2.7e-3 - S35 LFTPRGPS AGGGPGS - - - - - - - - - - - S42 SAGGGPGS GTSPQVE - - - - - - - - - - - S45 GGPGSGTS PQVEWTA -0.1 - - 0.64 - -0.032 0.49 -1.2e-14 - 0.1 2.3e-3 S85 AEVELAES GRRLRLP - - - - - - - - - - - S220 QYLAHVAS SPKGRKE - - - - - - - - - - - S221 YLAHVASS PKGRKEP 2.0e-5 - - 5.8e-15 - -0.074 - - - - - S337 LTNGPSSS PGQEREL - - - - - - - - - - - S358 SLRVLGFS HEEIISM - - - - - - - - - - - T390 ERNTDQAT MPDNTAA - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
T30
S35
S42
S45
S85
S220
S221
S337
S358
T390
T395
S466
Y599
Y605
S831
S942
S1029
S1030
S1328
T1330
T1462
S1535
T1566
S1767
S1785
S1969
S1980
S1983
S1989
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA T30 S35 S42 S45 S85 S220 S221 S337 S358 T390 T395 S466 Y599 Y605 S831 S942 S1029 S1030 S1328 T1330 T1462 S1535 T1566 S1767 S1785 S1969 S1980 S1983 S1989 protein RNA SCNV methylation CCRCC T30 S35 S42 S45 S85 S220 S221 S337 S358 T390 T395 S466 Y599 Y605 S831 S942 S1029 S1030 S1328 T1330 T1462 S1535 T1566 S1767 S1785 S1969 S1980 S1983 S1989 protein RNA SCNV methylation COAD T30 S35 S42 S45 S85 S220 S221 S337 S358 T390 T395 S466 Y599 Y605 S831 S942 S1029 S1030 S1328 T1330 T1462 S1535 T1566 S1767 S1785 S1969 S1980 S1983 S1989 protein RNA SCNV methylation GBM T30 S35 S42 S45 S85 S220 S221 S337 S358 T390 T395 S466 Y599 Y605 S831 S942 S1029 S1030 S1328 T1330 T1462 S1535 T1566 S1767 S1785 S1969 S1980 S1983 S1989 protein RNA SCNV methylation HNSCC T30 S35 S42 S45 S85 S220 S221 S337 S358 T390 T395 S466 Y599 Y605 S831 S942 S1029 S1030 S1328 T1330 T1462 S1535 T1566 S1767 S1785 S1969 S1980 S1983 S1989 protein RNA SCNV methylation LSCC T30 S35 S42 S45 S85 S220 S221 S337 S358 T390 T395 S466 Y599 Y605 S831 S942 S1029 S1030 S1328 T1330 T1462 S1535 T1566 S1767 S1785 S1969 S1980 S1983 S1989 protein RNA SCNV methylation LUAD T30 S35 S42 S45 S85 S220 S221 S337 S358 T390 T395 S466 Y599 Y605 S831 S942 S1029 S1030 S1328 T1330 T1462 S1535 T1566 S1767 S1785 S1969 S1980 S1983 S1989 protein RNA SCNV methylation OV T30 S35 S42 S45 S85 S220 S221 S337 S358 T390 T395 S466 Y599 Y605 S831 S942 S1029 S1030 S1328 T1330 T1462 S1535 T1566 S1767 S1785 S1969 S1980 S1983 S1989 protein RNA SCNV methylation PDAC T30 S35 S42 S45 S85 S220 S221 S337 S358 T390 T395 S466 Y599 Y605 S831 S942 S1029 S1030 S1328 T1330 T1462 S1535 T1566 S1767 S1785 S1969 S1980 S1983 S1989 protein RNA SCNV methylation UCEC T30 S35 S42 S45 S85 S220 S221 S337 S358 T390 T395 S466 Y599 Y605 S831 S942 S1029 S1030 S1328 T1330 T1462 S1535 T1566 S1767 S1785 S1969 S1980 S1983 S1989 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
T30
S35
S42
S45
S85
S220
S221
S337
S358
T390
T395
S466
Y599
Y605
S831
S942
S1029
S1030
S1328
T1330
T1462
S1535
T1566
S1767
S1785
S1969
S1980
S1983
S1989
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
Loading, please wait
all sites
T30
S35
S42
S45
S85
S220
S221
S337
S358
T390
T395
S466
Y599
Y605
S831
S942
S1029
S1030
S1328
T1330
T1462
S1535
T1566
S1767
S1785
S1969
S1980
S1983
S1989
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.