Protein: ENSP00000366237
Gene: DFFA

LinkedOmicsKB © 2022-2023 Zhang Lab

DFFA:
DNA fragmentation factor subunit alpha

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Structure

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
Y27PCLLRRNYSREQHGV718815-33--19-7334313432--52--
S28CLLRRNYSREQHGVA890096-8765--90-1086268635348--38158918
T57LAIDKSLTPVTLVLA19--------63----------
S99EKWAYNNSDGGTAWI241--1716------44--------
S107DGGTAWISQESFDVD860874-9472--63-312159545448--218-9
S110TAWISQESFDVDETD938931-1312--90-58331513161611432121716
S207EKEGSLLSKQEESKA212----------------426-
T231DTGISRETSSDVALA110------10-------------
S232TGISRETSSDVALAS7237--44--18-4526--1311534417407
S233GISRETSSDVALASH990687-9876--72-69408976666019664284214
Showing 1 to 10 of 14 rows
1025
rows per page

Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Y27PCLLRRNYSREQHGV4.6e-4-----0.0020.062---
S28CLLRRNYSREQHGVA1.2e-11--1.1e-4--1.8e-141.6e-86.1e-3-0.0020.18
T57LAIDKSLTPVTLVLA-----------
S99EKWAYNNSDGGTAWI-----------
S107DGGTAWISQESFDVD0.53-0.05---0.086-0.120.011---
S110TAWISQESFDVDETD0.23----0.7---0.19-
S207EKEGSLLSKQEESKA-----------
T231DTGISRETSSDVALA-----------
S232TGISRETSSDVALAS0.035----0.3---0.052-
S233GISRETSSDVALASH1.8e-4--4.6e-6--9.9e-36.3e-70.11-5.3e-50.58
Showing 1 to 10 of 14 rows
1025
rows per page

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAY27S28T57S99S107S110S207T231S232S233S257S302S305S315proteinRNASCNVmethylationCCRCCY27S28T57S99S107S110S207T231S232S233S257S302S305S315proteinRNASCNVmethylationCOADY27S28T57S99S107S110S207T231S232S233S257S302S305S315proteinRNASCNVmethylationGBMY27S28T57S99S107S110S207T231S232S233S257S302S305S315proteinRNASCNVmethylationHNSCCY27S28T57S99S107S110S207T231S232S233S257S302S305S315proteinRNASCNVmethylationLSCCY27S28T57S99S107S110S207T231S232S233S257S302S305S315proteinRNASCNVmethylationLUADY27S28T57S99S107S110S207T231S232S233S257S302S305S315proteinRNASCNVmethylationOVY27S28T57S99S107S110S207T231S232S233S257S302S305S315proteinRNASCNVmethylationPDACY27S28T57S99S107S110S207T231S232S233S257S302S305S315proteinRNASCNVmethylationUCECY27S28T57S99S107S110S207T231S232S233S257S302S305S315proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.