KAT5:
lysine acetyltransferase 5

Lollipop plot

Phosphosites location and occurrence

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Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Structure

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S86TKNGLPGSRPGSPER96626-44--99-98561089912127110041132
S90LPGSRPGSPEREVPA9123378-9976--99-108621089988816817105448318
S155KRKVEVVSPATPVPS930154-44--9-10825234440111257414
T158VEVVSPATPVPSETA961537-4744--18-28165348716435724109518
S190QPGRKRKSNCLGTDE828215-2019--62-54443943--1034014
T195RKSNCLGTDEDSQDS128----------1414--------
S199CLGTDEDSQDSSDGI969662-3939--45-77404944534733769275411
S202TDEDSQDSSDGIPSA929025-1212--18-40222423981142712367
S203DEDSQDSSDGIPSAP516122-108------25243532--41--
Showing 1 to 9 of 9 rows

Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S86TKNGLPGSRPGSPER1.6e-3----0.0146.9e-12---1.1e-4-
S90LPGSRPGSPEREVPA-0.82--6.2e-25--8.8e-43.4e-4-0.730.13-3.2e-30.013
S155KRKVEVVSPATPVPS-0.37-----0.74--0.12--0.76
T158VEVVSPATPVPSETA0.72-0.88---6.8e-4-0.79-0.8-4.1e-30.073
S190QPGRKRKSNCLGTDE-7.3e-3--2.9e-3----0.058---0.82
T195RKSNCLGTDEDSQDS-----------
S199CLGTDEDSQDSSDGI0.91--0.011---0.0810.0221.8e-4--0.0260.84
S202TDEDSQDSSDGIPSA6.7e-3----3.7e-37.1e-4---0.11-
S203DEDSQDSSDGIPSAP0.66------0.0162.5e-3---
Showing 1 to 9 of 9 rows

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAS86S90S155T158S190T195S199S202S203proteinRNASCNVmethylationCCRCCS86S90S155T158S190T195S199S202S203proteinRNASCNVmethylationCOADS86S90S155T158S190T195S199S202S203proteinRNASCNVmethylationGBMS86S90S155T158S190T195S199S202S203proteinRNASCNVmethylationHNSCCS86S90S155T158S190T195S199S202S203proteinRNASCNVmethylationLSCCS86S90S155T158S190T195S199S202S203proteinRNASCNVmethylationLUADS86S90S155T158S190T195S199S202S203proteinRNASCNVmethylationOVS86S90S155T158S190T195S199S202S203proteinRNASCNVmethylationPDACS86S90S155T158S190T195S199S202S203proteinRNASCNVmethylationUCECS86S90S155T158S190T195S199S202S203proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.