TGOLN2: trans-golgi network protein 2
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S56 RPGGSTKS HPEPQTP 1 26 - - - - - - - - - - 15 11 - - - - - - - - T62 KSHPEPQT PKDSPSK 2 35 - - - - - - 9 - - - 15 11 - - - - - - - - S70 PKDSPSKS SAEAQTP 5 84 - - 30 27 5 4 - - - - - - - - 6 - 5 1 6 - S71 KDSPSKSS AEAQTPE 10 1324 53 - 83 61 97 100 99 - 102 59 59 54 101 92 83 19 105 44 95 18 T76 KSSAEAQT PEDTPNK 6 162 47 - - - - - - - 10 7 15 14 8 8 - - 10 4 23 16 T80 EAQTPEDT PNKSGAE 4 100 - - 4 4 - - - - - - - - 9 8 - - 19 7 38 11 S136 ELQTPKDS TGKSGAE 1 22 - - - - - - - - - - - - - - - - 15 7 - - S154 PEDSPNRS GAEAKTQ 4 223 - - - - 1 7 72 - - - - - - - 40 8 66 29 - - T174 KSGSEAQT TKDVPNK 1 17 - - 9 8 - - - - - - - - - - - - - - - - T175 SGSEAQTT KDVPNKS 5 271 87 - 45 40 - - - - - - 34 30 5 4 - - 19 7 - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S56 RPGGSTKS HPEPQTP - - - - - - - - - - - T62 KSHPEPQT PKDSPSK - - - - - - - - - - - S70 PKDSPSKS SAEAQTP -2.5e-11 - -2.5e-11 - - - - - - - - S71 KDSPSKSS AEAQTPE -1.3e-4 - -4.6e-4 4.3e-7 - 0.76 -3.9e-3 0.092 0.69 -2.7e-11 -1.5e-7 T76 KSSAEAQT PEDTPNK -0.79 - - - - - - - - - -0.79 T80 EAQTPEDT PNKSGAE 3.6e-5 - - - - - - - - - 3.6e-5 S136 ELQTPKDS TGKSGAE - - - - - - - - - - - S154 PEDSPNRS GAEAKTQ -6.9e-8 - - - - - - - - -6.9e-8 - T174 KSGSEAQT TKDVPNK - - - - - - - - - - - T175 SGSEAQTT KDVPNKS 0.35 - -3.8e-3 - - - 2.4e-5 - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S56
T62
S70
S71
T76
T80
S136
S154
T174
T175
S182
T188
S196
S221
S224
S236
S245
S248
S258
S298
T302
S306
S314
T331
S337
S347
S349
S351
S352
S428
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S56 T62 S70 S71 T76 T80 S136 S154 T174 T175 S182 T188 S196 S221 S224 S236 S245 S248 S258 S298 T302 S306 S314 T331 S337 S347 S349 S351 S352 S428 protein RNA SCNV methylation CCRCC S56 T62 S70 S71 T76 T80 S136 S154 T174 T175 S182 T188 S196 S221 S224 S236 S245 S248 S258 S298 T302 S306 S314 T331 S337 S347 S349 S351 S352 S428 protein RNA SCNV methylation COAD S56 T62 S70 S71 T76 T80 S136 S154 T174 T175 S182 T188 S196 S221 S224 S236 S245 S248 S258 S298 T302 S306 S314 T331 S337 S347 S349 S351 S352 S428 protein RNA SCNV methylation GBM S56 T62 S70 S71 T76 T80 S136 S154 T174 T175 S182 T188 S196 S221 S224 S236 S245 S248 S258 S298 T302 S306 S314 T331 S337 S347 S349 S351 S352 S428 protein RNA SCNV methylation HNSCC S56 T62 S70 S71 T76 T80 S136 S154 T174 T175 S182 T188 S196 S221 S224 S236 S245 S248 S258 S298 T302 S306 S314 T331 S337 S347 S349 S351 S352 S428 protein RNA SCNV methylation LSCC S56 T62 S70 S71 T76 T80 S136 S154 T174 T175 S182 T188 S196 S221 S224 S236 S245 S248 S258 S298 T302 S306 S314 T331 S337 S347 S349 S351 S352 S428 protein RNA SCNV methylation LUAD S56 T62 S70 S71 T76 T80 S136 S154 T174 T175 S182 T188 S196 S221 S224 S236 S245 S248 S258 S298 T302 S306 S314 T331 S337 S347 S349 S351 S352 S428 protein RNA SCNV methylation OV S56 T62 S70 S71 T76 T80 S136 S154 T174 T175 S182 T188 S196 S221 S224 S236 S245 S248 S258 S298 T302 S306 S314 T331 S337 S347 S349 S351 S352 S428 protein RNA SCNV methylation PDAC S56 T62 S70 S71 T76 T80 S136 S154 T174 T175 S182 T188 S196 S221 S224 S236 S245 S248 S258 S298 T302 S306 S314 T331 S337 S347 S349 S351 S352 S428 protein RNA SCNV methylation UCEC S56 T62 S70 S71 T76 T80 S136 S154 T174 T175 S182 T188 S196 S221 S224 S236 S245 S248 S258 S298 T302 S306 S314 T331 S337 S347 S349 S351 S352 S428 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S56
T62
S70
S71
T76
T80
S136
S154
T174
T175
S182
T188
S196
S221
S224
S236
S245
S248
S258
S298
T302
S306
S314
T331
S337
S347
S349
S351
S352
S428
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S56
T62
S70
S71
T76
T80
S136
S154
T174
T175
S182
T188
S196
S221
S224
S236
S245
S248
S258
S298
T302
S306
S314
T331
S337
S347
S349
S351
S352
S428
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.