ERRFI1: ERBB receptor feedback inhibitor 1
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
2rf9 chain C
2rf9 chain D
2rfd chain C
2rfd chain D
2rfe chain E
2rfe chain F
4i21 chain C
4i21 chain D
4r3p chain B
4r3r chain B
4zjv chain C
4zjv chain D
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
Loading, please wait
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S91 NGPSQKSS LPPLLIP 1 18 - - - - - - - - - - - - 10 8 - - - - - - T127 VNGVCAST PPLTPIK 10 973 98 - 71 66 16 19 64 - 39 23 70 65 110 100 18 6 80 33 79 16 T131 CASTPPLT PIKNSPS 10 613 47 - 9 7 16 19 80 - 17 10 45 41 61 55 7 2 88 37 58 14 S136 PLTPIKNS PSLFPCA 3 25 - - 4 3 - - - - - - - - 5 4 - - - - 7 2 S138 TPIKNSPS LFPCAPL 1 25 - - - - - - - - - - - - 13 12 - - - - - - T214 INYAYFDT PAVSAAD 1 9 - - - - - - - - 6 3 - - - - - - - - - - S249 THRRLRRS HSGPAGS 1 8 - - - - - - - - - - - - 4 4 - - - - - - S251 RRLRRSHS GPAGSFN 10 1392 116 - 99 76 85 84 71 - 108 62 108 99 110 101 48 11 105 44 54 11 S256 SHSGPAGS FNKPAIR 7 132 8 - 16 16 5 4 9 - - - 5 4 10 8 - - - - 35 12 S265 NKPAIRIS NCCIHRA 3 112 - - - - - - - - - - 20 17 23 20 27 5 - - - -
Tumor and normal comparison
Loading, please wait
Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S91 NGPSQKSS LPPLLIP - - - - - - - - - - - T127 VNGVCAST PPLTPIK 3.8e-10 - 2.9e-8 - - -0.018 0.082 8.1e-23 - 0.039 -0.14 T131 CASTPPLT PIKNSPS 9.3e-3 - - - - - -0.1 5.6e-12 - 0.76 -0.72 S136 PLTPIKNS PSLFPCA - - - - - - - - - - - S138 TPIKNSPS LFPCAPL - - - - - - - - - - - T214 INYAYFDT PAVSAAD - - - - - - - - - - - S249 THRRLRRS HSGPAGS - - - - - - - - - - - S251 RRLRRSHS GPAGSFN 2.1e-49 - 2.5e-8 9.5e-15 - 6.2e-21 7.8e-4 1.5e-21 0.027 2.7e-7 -0.24 S256 SHSGPAGS FNKPAIR 0.18 - - - - - - - - - 0.18 S265 NKPAIRIS NCCIHRA 5.8e-3 - - - - - 0.056 0.046 - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
Loading, please wait
all sites
S91
T127
T131
S136
S138
T214
S249
S251
S256
S265
S273
S276
S302
S326
S328
S330
T332
S334
S337
Y341
S369
S374
Y394
S457
S461
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S91 T127 T131 S136 S138 T214 S249 S251 S256 S265 S273 S276 S302 S326 S328 S330 T332 S334 S337 Y341 S369 S374 Y394 S457 S461 protein RNA SCNV methylation CCRCC S91 T127 T131 S136 S138 T214 S249 S251 S256 S265 S273 S276 S302 S326 S328 S330 T332 S334 S337 Y341 S369 S374 Y394 S457 S461 protein RNA SCNV methylation COAD S91 T127 T131 S136 S138 T214 S249 S251 S256 S265 S273 S276 S302 S326 S328 S330 T332 S334 S337 Y341 S369 S374 Y394 S457 S461 protein RNA SCNV methylation GBM S91 T127 T131 S136 S138 T214 S249 S251 S256 S265 S273 S276 S302 S326 S328 S330 T332 S334 S337 Y341 S369 S374 Y394 S457 S461 protein RNA SCNV methylation HNSCC S91 T127 T131 S136 S138 T214 S249 S251 S256 S265 S273 S276 S302 S326 S328 S330 T332 S334 S337 Y341 S369 S374 Y394 S457 S461 protein RNA SCNV methylation LSCC S91 T127 T131 S136 S138 T214 S249 S251 S256 S265 S273 S276 S302 S326 S328 S330 T332 S334 S337 Y341 S369 S374 Y394 S457 S461 protein RNA SCNV methylation LUAD S91 T127 T131 S136 S138 T214 S249 S251 S256 S265 S273 S276 S302 S326 S328 S330 T332 S334 S337 Y341 S369 S374 Y394 S457 S461 protein RNA SCNV methylation OV S91 T127 T131 S136 S138 T214 S249 S251 S256 S265 S273 S276 S302 S326 S328 S330 T332 S334 S337 Y341 S369 S374 Y394 S457 S461 protein RNA SCNV methylation PDAC S91 T127 T131 S136 S138 T214 S249 S251 S256 S265 S273 S276 S302 S326 S328 S330 T332 S334 S337 Y341 S369 S374 Y394 S457 S461 protein RNA SCNV methylation UCEC S91 T127 T131 S136 S138 T214 S249 S251 S256 S265 S273 S276 S302 S326 S328 S330 T332 S334 S337 Y341 S369 S374 Y394 S457 S461 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
Loading, please wait
all sites
S91
T127
T131
S136
S138
T214
S249
S251
S256
S265
S273
S276
S302
S326
S328
S330
T332
S334
S337
Y341
S369
S374
Y394
S457
S461
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
Loading, please wait
all sites
S91
T127
T131
S136
S138
T214
S249
S251
S256
S265
S273
S276
S302
S326
S328
S330
T332
S334
S337
Y341
S369
S374
Y394
S457
S461
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.