TBC1D4: TBC1 domain family member 4
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
3qyb chain A
7nix chain B
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S44 RLWYVGGS CLDHRTT 1 45 - - 23 22 - - - - - - - - - - - - - - - - S102 PAPGAGAS GGTSPSA 2 25 - - - - - - 9 - - - - - 8 8 - - - - - - T105 GAGASGGT SPSATQP 5 46 7 - 4 4 - - - - - - 5 5 5 4 - - 8 4 - - S106 AGASGGTS PSATQPN 10 1022 28 - 74 60 91 87 89 - 108 62 49 46 42 36 32 8 96 41 64 9 S108 ASGGTSPS ATQPNPA 7 240 25 - 37 32 3 6 - - 54 35 10 9 12 11 - - - - 6 - T110 GGTSPSAT QPNPAVF 1 10 - - - - - - - - 6 4 - - - - - - - - - - S220 THKKAPSS LIDDCME 1 8 - - 4 4 - - - - - - - - - - - - - - - - S230 DDCMEKFS LHEQQRL 1 8 - - 4 4 - - - - - - - - - - - - - - - - S262 LEVVVPGS PGDCLPE 10 1070 75 - 103 80 62 71 28 - 107 62 74 64 81 76 6 2 91 35 46 7 T274 LPEEADGT DTHLGLP 3 42 - - 4 4 - - - - 17 9 - - 4 4 - - - - - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S44 RLWYVGGS CLDHRTT 0.46 - 0.46 - - - - - - - - S102 PAPGAGAS GGTSPSA - - - - - - - - - - - T105 GAGASGGT SPSATQP - - - - - - - - - - - S106 AGASGGTS PSATQPN -2.3e-15 - -2.3e-11 4.1e-5 - -6.5e-6 -6.6e-3 -3.7e-4 - -1.6e-9 - S108 ASGGTSPS ATQPNPA -8.6e-8 - -4.2e-6 - - -0.003 - - - - - T110 GGTSPSAT QPNPAVF - - - - - - - - - - - S220 THKKAPSS LIDDCME - - - - - - - - - - - S230 DDCMEKFS LHEQQRL - - - - - - - - - - - S262 LEVVVPGS PGDCLPE -1.6e-8 - -4.7e-8 0.8 - -0.11 -0.29 -8.4e-16 - 0.042 - T274 LPEEADGT DTHLGLP - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S44
S102
T105
S106
S108
T110
S220
S230
S262
T274
T276
S285
S314
S318
S341
S344
S370
S485
S486
S566
T568
S569
S570
S588
S591
S595
S597
S600
S605
S609
T613
S617
S620
S621
T625
T642
S644
S648
S649
S666
S673
S725
S741
S750
S751
T752
S754
S757
T766
S782
S787
S789
S809
T811
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S44 S102 T105 S106 S108 T110 S220 S230 S262 T274 T276 S285 S314 S318 S341 S344 S370 S485 S486 S566 T568 S569 S570 S588 S591 S595 S597 S600 S605 S609 T613 S617 S620 S621 T625 T642 S644 S648 S649 S666 S673 S725 S741 S750 S751 T752 S754 S757 T766 S782 S787 S789 S809 T811 protein RNA SCNV methylation CCRCC S44 S102 T105 S106 S108 T110 S220 S230 S262 T274 T276 S285 S314 S318 S341 S344 S370 S485 S486 S566 T568 S569 S570 S588 S591 S595 S597 S600 S605 S609 T613 S617 S620 S621 T625 T642 S644 S648 S649 S666 S673 S725 S741 S750 S751 T752 S754 S757 T766 S782 S787 S789 S809 T811 protein RNA SCNV methylation COAD S44 S102 T105 S106 S108 T110 S220 S230 S262 T274 T276 S285 S314 S318 S341 S344 S370 S485 S486 S566 T568 S569 S570 S588 S591 S595 S597 S600 S605 S609 T613 S617 S620 S621 T625 T642 S644 S648 S649 S666 S673 S725 S741 S750 S751 T752 S754 S757 T766 S782 S787 S789 S809 T811 protein RNA SCNV methylation GBM S44 S102 T105 S106 S108 T110 S220 S230 S262 T274 T276 S285 S314 S318 S341 S344 S370 S485 S486 S566 T568 S569 S570 S588 S591 S595 S597 S600 S605 S609 T613 S617 S620 S621 T625 T642 S644 S648 S649 S666 S673 S725 S741 S750 S751 T752 S754 S757 T766 S782 S787 S789 S809 T811 protein RNA SCNV methylation HNSCC S44 S102 T105 S106 S108 T110 S220 S230 S262 T274 T276 S285 S314 S318 S341 S344 S370 S485 S486 S566 T568 S569 S570 S588 S591 S595 S597 S600 S605 S609 T613 S617 S620 S621 T625 T642 S644 S648 S649 S666 S673 S725 S741 S750 S751 T752 S754 S757 T766 S782 S787 S789 S809 T811 protein RNA SCNV methylation LSCC S44 S102 T105 S106 S108 T110 S220 S230 S262 T274 T276 S285 S314 S318 S341 S344 S370 S485 S486 S566 T568 S569 S570 S588 S591 S595 S597 S600 S605 S609 T613 S617 S620 S621 T625 T642 S644 S648 S649 S666 S673 S725 S741 S750 S751 T752 S754 S757 T766 S782 S787 S789 S809 T811 protein RNA SCNV methylation LUAD S44 S102 T105 S106 S108 T110 S220 S230 S262 T274 T276 S285 S314 S318 S341 S344 S370 S485 S486 S566 T568 S569 S570 S588 S591 S595 S597 S600 S605 S609 T613 S617 S620 S621 T625 T642 S644 S648 S649 S666 S673 S725 S741 S750 S751 T752 S754 S757 T766 S782 S787 S789 S809 T811 protein RNA SCNV methylation OV S44 S102 T105 S106 S108 T110 S220 S230 S262 T274 T276 S285 S314 S318 S341 S344 S370 S485 S486 S566 T568 S569 S570 S588 S591 S595 S597 S600 S605 S609 T613 S617 S620 S621 T625 T642 S644 S648 S649 S666 S673 S725 S741 S750 S751 T752 S754 S757 T766 S782 S787 S789 S809 T811 protein RNA SCNV methylation PDAC S44 S102 T105 S106 S108 T110 S220 S230 S262 T274 T276 S285 S314 S318 S341 S344 S370 S485 S486 S566 T568 S569 S570 S588 S591 S595 S597 S600 S605 S609 T613 S617 S620 S621 T625 T642 S644 S648 S649 S666 S673 S725 S741 S750 S751 T752 S754 S757 T766 S782 S787 S789 S809 T811 protein RNA SCNV methylation UCEC S44 S102 T105 S106 S108 T110 S220 S230 S262 T274 T276 S285 S314 S318 S341 S344 S370 S485 S486 S566 T568 S569 S570 S588 S591 S595 S597 S600 S605 S609 T613 S617 S620 S621 T625 T642 S644 S648 S649 S666 S673 S725 S741 S750 S751 T752 S754 S757 T766 S782 S787 S789 S809 T811 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S44
S102
T105
S106
S108
T110
S220
S230
S262
T274
T276
S285
S314
S318
S341
S344
S370
S485
S486
S566
T568
S569
S570
S588
S591
S595
S597
S600
S605
S609
T613
S617
S620
S621
T625
T642
S644
S648
S649
S666
S673
S725
S741
S750
S751
T752
S754
S757
T766
S782
S787
S789
S809
T811
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
Loading, please wait
all sites
S44
S102
T105
S106
S108
T110
S220
S230
S262
T274
T276
S285
S314
S318
S341
S344
S370
S485
S486
S566
T568
S569
S570
S588
S591
S595
S597
S600
S605
S609
T613
S617
S620
S621
T625
T642
S644
S648
S649
S666
S673
S725
S741
S750
S751
T752
S754
S757
T766
S782
S787
S789
S809
T811
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.