DPP6: dipeptidyl peptidase like 6
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
1xfd chain A
1xfd chain B
1xfd chain C
1xfd chain D
7e87 chain E
7e87 chain F
7e87 chain I
7e87 chain J
7e89 chain A
7e89 chain B
7e89 chain I
7e89 chain J
7e8b chain I
7e8b chain J
7e8b chain K
7e8b chain L
7e8e chain I
7e8e chain J
7e8e chain K
7e8e chain L
7e8g chain I
7e8g chain J
7e8g chain K
7e8g chain L
7e8h chain I
7e8h chain J
7e8h chain K
7e8h chain L
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S17 GKINTSRS FPAPPEA 2 24 - - - - 4 5 15 - - - - - - - - - - - - - S238 SLDPPEVS NAKLQYA 1 27 - - - - - - 27 - - - - - - - - - - - - - S426 TKKHEDES EAWLHRQ 1 54 - - - - - - 54 - - - - - - - - - - - - - T578 KKMFDLET NEHVKKA 1 19 - - - - - - 19 - - - - - - - - - - - - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S17 GKINTSRS FPAPPEA - - - - - - - - - - - S238 SLDPPEVS NAKLQYA - - - - - - - - - - - S426 TKKHEDES EAWLHRQ - - - - - - - - - - - T578 KKMFDLET NEHVKKA - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S17
S238
S426
T578
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S17 S238 S426 T578 protein RNA SCNV methylation CCRCC S17 S238 S426 T578 protein RNA SCNV methylation COAD S17 S238 S426 T578 protein RNA SCNV methylation GBM S17 S238 S426 T578 protein RNA SCNV methylation HNSCC S17 S238 S426 T578 protein RNA SCNV methylation LSCC S17 S238 S426 T578 protein RNA SCNV methylation LUAD S17 S238 S426 T578 protein RNA SCNV methylation OV S17 S238 S426 T578 protein RNA SCNV methylation PDAC S17 S238 S426 T578 protein RNA SCNV methylation UCEC S17 S238 S426 T578 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S17
S238
S426
T578
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S17
S238
S426
T578
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.