Protein: ENSP00000367207
Gene: MYC

LinkedOmicsKB © 2022-2023 Zhang Lab

MYC:
MYC proto-oncogene, bHLH transcription factor

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Structure

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S6__MPLNVSFTNRNYD229--------64109--------
T58KKFELLPTPPLSPSR7824--9572--36-864993858581--53205316
S62LLPTPPLSPSRRSGL7839--6653--28-10259108999284--50206018
S67PLSPSRRSGLCSPSY19-------------------9
S71SRRSGLCSPSYVAVT7423--1312--27-523139365447--2811649
S159YQAARKDSGSPNPAR348--------16955----94--
S161AARKDSGSPNPARGH5303--------2014555043--67304911
S293GHSKPPHSPLVLKRC2168-------53----------
S344SNNRKCTSPRSSDTE7309----586727-1810302854--514313
S347RKCTSPRSSDTEENV6121--441421--2412551412----6-
Showing 1 to 10 of 11 rows
1025
rows per page

Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S6__MPLNVSFTNRNYD-----------
T58KKFELLPTPPLSPSR1.9e-25-1.8e-7--7.6e-73.9e-105.1e-6-3.4e-6-0.93
S62LLPTPPLSPSRRSGL1.6e-18-1.1e-8--0.0513.1e-110.22-1.2e-30.006
S67PLSPSRRSGLCSPSY-----------
S71SRRSGLCSPSYVAVT-0.59-----0.220.55-0.23-0.45-
S159YQAARKDSGSPNPAR-----------
S161AARKDSGSPNPARGH0.001----1.7e-36.5e-12---0.17-0.04
S293GHSKPPHSPLVLKRC-----------
S344SNNRKCTSPRSSDTE3.1e-15--2e-20--1.1e-8----0.19
S347RKCTSPRSSDTEENV0.062----0.062-----
Showing 1 to 10 of 11 rows
1025
rows per page

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAS6T58S62S71S159S161S293S344S347S348proteinRNASCNVmethylationCCRCCS6T58S62S71S159S161S293S344S347S348proteinRNASCNVmethylationCOADS6T58S62S71S159S161S293S344S347S348proteinRNASCNVmethylationGBMS6T58S62S71S159S161S293S344S347S348proteinRNASCNVmethylationHNSCCS6T58S62S71S159S161S293S344S347S348proteinRNASCNVmethylationLSCCS6T58S62S71S159S161S293S344S347S348proteinRNASCNVmethylationLUADS6T58S62S71S159S161S293S344S347S348proteinRNASCNVmethylationOVS6T58S62S71S159S161S293S344S347S348proteinRNASCNVmethylationPDACS6T58S62S71S159S161S293S344S347S348proteinRNASCNVmethylationUCECS6T58S62S71S159S161S293S344S347S348proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.