Protein: ENSP00000367398
Gene: NPHP4

LinkedOmicsKB © 2022-2023 Zhang Lab

NPHP4:
nephrocystin 4

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S142IFSNQPDSPISASQD10115383-103805480-332098891101017616100429518
S431KVPSASMSSEEVKQV19------9-------------
S451RFQFSLGSEEHLDAP937332-3127--55-6430294440124104432
T477RPSRKPPTSPSSPPA324------9-----54--42--
S478PSRKPPTSPSSPPAP970054-7562--9-2618797178722247429252
S480RKPPTSPSSPPAPVP219------------44--92--
S481KPPTSPSSPPAPVPR1041324-54728-2312494661563494018132
S496VLAAPQNSPVGPGLS718322-----9---99171519552629
S510SISQLAASPRSPTQH221----------54------12-
S513QLAASPRSPTQHCLA5300------27---343021207518--669
Showing 1 to 10 of 16 rows
1025
rows per page

Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S142IFSNQPDSPISASQD-1.1e-16--0.24--0.27-2.9e-18-5.2e-18-0.049-2.5e-96.3e-4
S431KVPSASMSSEEVKQV-----------
S451RFQFSLGSEEHLDAP-1e-9--0.029----7.3e-7-5.7e-4---
T477RPSRKPPTSPSSPPA-----------
S478PSRKPPTSPSSPPAP-7e-12--0.054--0.33-4.3e-8-4.8e-4--5.9e-8-
S480RKPPTSPSSPPAPVP-----------
S481KPPTSPSSPPAPVPR-1.1e-8----0.13-1.6e-6-3.4e-7--2.3e-3-
S496VLAAPQNSPVGPGLS-----------
S510SISQLAASPRSPTQH-----------
S513QLAASPRSPTQHCLA-1.5e-3------6.6e-7-0.160.39--
Showing 1 to 10 of 16 rows
1025
rows per page

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAS142S431S451T477S478S480S481S496S510S513S597S603S862T866S868T1353proteinRNASCNVmethylationCCRCCS142S431S451T477S478S480S481S496S510S513S597S603S862T866S868T1353proteinRNASCNVmethylationCOADS142S431S451T477S478S480S481S496S510S513S597S603S862T866S868T1353proteinRNASCNVmethylationGBMS142S431S451T477S478S480S481S496S510S513S597S603S862T866S868T1353proteinRNASCNVmethylationHNSCCS142S431S451T477S478S480S481S496S510S513S597S603S862T866S868T1353proteinRNASCNVmethylationLSCCS142S431S451T477S478S480S481S496S510S513S597S603S862T866S868T1353proteinRNASCNVmethylationLUADS142S431S451T477S478S480S481S496S510S513S597S603S862T866S868T1353proteinRNASCNVmethylationOVS142S431S451T477S478S480S481S496S510S513S597S603S862T866S868T1353proteinRNASCNVmethylationPDACS142S431S451T477S478S480S481S496S510S513S597S603S862T866S868T1353proteinRNASCNVmethylationUCECS142S431S451T477S478S480S481S496S510S513S597S603S862T866S868T1353proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.