Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
2hkf chain P
3iai chain A
3iai chain B
3iai chain C
3iai chain D
5dvx chain A
5dvx chain B
5fl4 chain A
5fl4 chain B
5fl4 chain C
5fl4 chain D
5fl5 chain A
5fl5 chain B
5fl5 chain C
5fl5 chain D
5fl6 chain A
5fl6 chain B
5fl6 chain C
5fl6 chain D
6fe0 chain A
6fe0 chain B
6fe0 chain C
6fe0 chain D
6fe1 chain A
6fe1 chain B
6fe1 chain C
6fe1 chain D
6fe2 chain A
6fe2 chain B
6fe2 chain C
6fe2 chain D
6g98 chain A
6g98 chain B
6g98 chain C
6g98 chain D
6g9u chain A
6g9u chain B
6g9u chain C
6g9u chain D
6qn2 chain A
6qn2 chain B
6qn2 chain C
6qn2 chain D
6qn5 chain A
6qn5 chain B
6qn5 chain C
6qn5 chain D
6qn6 chain A
6qn6 chain B
6qn6 chain C
6qn6 chain D
6qut chain A
6qut chain B
6qut chain C
6qut chain D
6rqn chain A
6rqq chain A
6rqq chain C
6rqu chain A
6rqw chain A
6tl5 chain A
6tl5 chain B
6tl5 chain C
6tl5 chain D
6tl6 chain A
6tl6 chain B
6tl6 chain C
6tl6 chain D
6y74 chain A
6y74 chain B
7pom chain A
7pom chain B
7pom chain C
7pom chain D
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S53 DSPLGGGS SGEDDPL 3 30 - - 8 6 - - - - 7 2 - - 4 3 - - - - - - S54 SPLGGGSS GEDDPLG 4 63 - - 8 8 - - - - 17 9 10 7 3 1 - - - - - - S67 LGEEDLPS EEDSPRE 7 162 - - 21 20 - - 36 - 7 3 10 8 8 8 - - 14 4 18 5 S102 LPEVKPKS EEEGSLK 8 643 - - 66 52 - - 99 - 76 42 20 17 21 17 15 2 100 41 66 9 S139 DKEGDDQS HWRYGGD 1 8 - - 8 - - - - - - - - - - - - - - - - - S448 RGTKGGVS YRPAEVA 4 181 - - - - 4 5 46 - - - - - - - 49 11 - - 59 7 Y449 GTKGGVSY RPAEVAE 1 8 - - - - - - - - - - - - - - - - 6 2 - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S53 DSPLGGGS SGEDDPL - - - - - - - - - - - S54 SPLGGGSS GEDDPLG - - - - - - - - - - - S67 LGEEDLPS EEDSPRE 0.023 - 0.023 - - - - - - - - S102 LPEVKPKS EEEGSLK 2.2e-22 - 1.2e-18 - - 1.3e-9 0.33 0.011 - 7.9e-4 - S139 DKEGDDQS HWRYGGD - - - - - - - - - - - S448 RGTKGGVS YRPAEVA -0.53 - - - - - - - -0.53 - - Y449 GTKGGVSY RPAEVAE - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S53
S54
S67
S102
S139
S448
Y449
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S53 S54 S67 S102 S139 S448 Y449 protein RNA SCNV methylation CCRCC S53 S54 S67 S102 S139 S448 Y449 protein RNA SCNV methylation COAD S53 S54 S67 S102 S139 S448 Y449 protein RNA SCNV methylation GBM S53 S54 S67 S102 S139 S448 Y449 protein RNA SCNV methylation HNSCC S53 S54 S67 S102 S139 S448 Y449 protein RNA SCNV methylation LSCC S53 S54 S67 S102 S139 S448 Y449 protein RNA SCNV methylation LUAD S53 S54 S67 S102 S139 S448 Y449 protein RNA SCNV methylation OV S53 S54 S67 S102 S139 S448 Y449 protein RNA SCNV methylation PDAC S53 S54 S67 S102 S139 S448 Y449 protein RNA SCNV methylation UCEC S53 S54 S67 S102 S139 S448 Y449 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S53
S54
S67
S102
S139
S448
Y449
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S53
S54
S67
S102
S139
S448
Y449
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.