Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
2n1l chain A
3bim chain I
3bim chain J
3bim chain K
3bim chain L
3bim chain M
3bim chain N
3bim chain O
3bim chain P
4hpl chain A
6b7g chain B
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S177 RPASDKQS PLNINGA 7 200 - - 39 20 5 4 9 - 6 3 40 34 14 12 - - - - 11 3 S235 SLAQPLYS PVCTNGE 1 22 - - - - - - - - - - - - - - - - - - 17 5 S336 TALLLPPS PRPSPRV 9 901 - - 88 65 11 7 10 - 80 43 84 77 93 84 53 15 75 30 68 18 S340 LPPSPRPS PRVHLPT 2 28 - - - - - - - - - - 5 4 - - - - - - 19 - S367 HYARISTS PSVALSK 8 609 - - 51 48 - - 18 - 35 19 63 60 85 77 7 2 40 16 70 18 S373 TSPSVALS KPYMTVS 1 8 - - - - - - - - - - - - - - 7 1 - - - - S423 QDRKDGSS PPLLEKQ 9 1398 - - 103 80 97 100 90 - 108 62 108 99 110 101 69 15 101 42 95 18 S473 LVHSRAGS GLVLSGS 1 25 - - - - - - - - - - - - - - - - - - 18 7 S488 EIPKETLS PPGNGCA 9 532 - - 29 27 24 21 45 - 30 19 73 66 38 31 14 3 5 2 87 18 S508 IISTAPSS WVVPGPS 1 15 - - - - - - - - - - - - - - - - - - 13 2
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S177 RPASDKQS PLNINGA 1.7e-3 - 0.76 - - - 3.6e-5 - - - - S235 SLAQPLYS PVCTNGE - - - - - - - - - - - S336 TALLLPPS PRPSPRV 0.16 - 5.0e-4 - - -4.5e-6 0.076 2.1e-6 0.99 -9.4e-6 6.5e-3 S340 LPPSPRPS PRVHLPT - - - - - - - - - - - S367 HYARISTS PSVALSK 6.8e-7 - 3.1e-5 - - -2.4e-4 0.7 4.7e-7 - 9.7e-7 0.18 S373 TSPSVALS KPYMTVS - - - - - - - - - - - S423 QDRKDGSS PPLLEKQ 3.4e-25 - -3.5e-4 3e-24 - -0.52 2.3e-25 4.8e-22 6.0e-4 -9.7e-4 1.4e-3 S473 LVHSRAGS GLVLSGS - - - - - - - - - - - S488 EIPKETLS PPGNGCA 3.9e-3 - -0.68 0.26 - 0.22 0.83 0.022 - - 8.7e-3 S508 IISTAPSS WVVPGPS - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S177
S235
S336
S340
S367
S373
S423
S473
S488
S508
S515
T555
S558
S560
S563
S569
S571
S669
S1047
S1064
S1122
S1127
S1139
S1142
S1143
T1145
T1147
T1148
S1166
S1269
S1271
S1288
S1290
S1404
S1405
Y1407
S1410
S1439
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S177 S235 S336 S340 S367 S373 S423 S473 S488 S508 S515 T555 S558 S560 S563 S569 S571 S669 S1047 S1064 S1122 S1127 S1139 S1142 S1143 T1145 T1147 T1148 S1166 S1269 S1271 S1288 S1290 S1404 S1405 Y1407 S1410 S1439 protein RNA SCNV methylation CCRCC S177 S235 S336 S340 S367 S373 S423 S473 S488 S508 S515 T555 S558 S560 S563 S569 S571 S669 S1047 S1064 S1122 S1127 S1139 S1142 S1143 T1145 T1147 T1148 S1166 S1269 S1271 S1288 S1290 S1404 S1405 Y1407 S1410 S1439 protein RNA SCNV methylation COAD S177 S235 S336 S340 S367 S373 S423 S473 S488 S508 S515 T555 S558 S560 S563 S569 S571 S669 S1047 S1064 S1122 S1127 S1139 S1142 S1143 T1145 T1147 T1148 S1166 S1269 S1271 S1288 S1290 S1404 S1405 Y1407 S1410 S1439 protein RNA SCNV methylation GBM S177 S235 S336 S340 S367 S373 S423 S473 S488 S508 S515 T555 S558 S560 S563 S569 S571 S669 S1047 S1064 S1122 S1127 S1139 S1142 S1143 T1145 T1147 T1148 S1166 S1269 S1271 S1288 S1290 S1404 S1405 Y1407 S1410 S1439 protein RNA SCNV methylation HNSCC S177 S235 S336 S340 S367 S373 S423 S473 S488 S508 S515 T555 S558 S560 S563 S569 S571 S669 S1047 S1064 S1122 S1127 S1139 S1142 S1143 T1145 T1147 T1148 S1166 S1269 S1271 S1288 S1290 S1404 S1405 Y1407 S1410 S1439 protein RNA SCNV methylation LSCC S177 S235 S336 S340 S367 S373 S423 S473 S488 S508 S515 T555 S558 S560 S563 S569 S571 S669 S1047 S1064 S1122 S1127 S1139 S1142 S1143 T1145 T1147 T1148 S1166 S1269 S1271 S1288 S1290 S1404 S1405 Y1407 S1410 S1439 protein RNA SCNV methylation LUAD S177 S235 S336 S340 S367 S373 S423 S473 S488 S508 S515 T555 S558 S560 S563 S569 S571 S669 S1047 S1064 S1122 S1127 S1139 S1142 S1143 T1145 T1147 T1148 S1166 S1269 S1271 S1288 S1290 S1404 S1405 Y1407 S1410 S1439 protein RNA SCNV methylation OV S177 S235 S336 S340 S367 S373 S423 S473 S488 S508 S515 T555 S558 S560 S563 S569 S571 S669 S1047 S1064 S1122 S1127 S1139 S1142 S1143 T1145 T1147 T1148 S1166 S1269 S1271 S1288 S1290 S1404 S1405 Y1407 S1410 S1439 protein RNA SCNV methylation PDAC S177 S235 S336 S340 S367 S373 S423 S473 S488 S508 S515 T555 S558 S560 S563 S569 S571 S669 S1047 S1064 S1122 S1127 S1139 S1142 S1143 T1145 T1147 T1148 S1166 S1269 S1271 S1288 S1290 S1404 S1405 Y1407 S1410 S1439 protein RNA SCNV methylation UCEC S177 S235 S336 S340 S367 S373 S423 S473 S488 S508 S515 T555 S558 S560 S563 S569 S571 S669 S1047 S1064 S1122 S1127 S1139 S1142 S1143 T1145 T1147 T1148 S1166 S1269 S1271 S1288 S1290 S1404 S1405 Y1407 S1410 S1439 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S177
S235
S336
S340
S367
S373
S423
S473
S488
S508
S515
T555
S558
S560
S563
S569
S571
S669
S1047
S1064
S1122
S1127
S1139
S1142
S1143
T1145
T1147
T1148
S1166
S1269
S1271
S1288
S1290
S1404
S1405
Y1407
S1410
S1439
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
Loading, please wait
all sites
S177
S235
S336
S340
S367
S373
S423
S473
S488
S508
S515
T555
S558
S560
S563
S569
S571
S669
S1047
S1064
S1122
S1127
S1139
S1142
S1143
T1145
T1147
T1148
S1166
S1269
S1271
S1288
S1290
S1404
S1405
Y1407
S1410
S1439
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.