Protein: ENSP00000367787

LIG3:: DNA ligase 3

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Structure

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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				BRCA		CCRCC		COAD		GBM		HNSCC		LSCC		LUAD		OV		PDAC		UCEC
Site	Sequence	Cohorts	Total	T	N	T	N	T	N	T	N	T	N	T	N	T	N	T	N	T	N	T	N
S130	VPNPFSESGGDMKEW	1	45	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	34	11
T209	LTTTGQVTSPVKGAS	4	35	9	-	-	-	5	4	-	-	-	-	-	-	4	4	8	1	-	-	-	-
S210	TTTGQVTSPVKGASF	10	957	40	-	16	16	90	89	99	-	40	24	50	45	56	51	83	19	88	38	95	18
S227	STNPRKFSGFSAKPN	8	622	-	-	9	6	-	-	90	-	96	56	10	8	69	64	7	1	86	37	67	16
S236	FSAKPNNSGEAPSSP	4	105	40	-	9	7	-	-	-	-	6	4	20	19	-	-	-	-	-	-	-	-
S241	NNSGEAPSSPTPKRS	4	75	40	-	-	-	-	-	-	-	-	-	5	5	9	7	8	1	-	-	-	-
S242	NSGEAPSSPTPKRSL	10	1298	96	-	64	52	92	96	99	-	67	41	83	76	93	84	76	17	105	44	95	18
T317	LLPGVIKTVYNLNDK	5	222	-	-	-	-	-	-	-	-	97	55	5	4	-	-	6	2	33	14	6	-
S472	PGQRRALSVQASLMT	8	895	59	-	63	48	15	12	-	-	102	59	94	86	105	97	-	-	65	29	45	16
S476	RALSVQASLMTPVQP	1	21	21	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-

Showing 1 to 10 of 18 rows

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Tumor and normal comparison

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Site	Sequence	Meta P	BRCA	CCRCC	COAD	GBM	HNSCC	LSCC	LUAD	OV	PDAC	UCEC
S130	VPNPFSESGGDMKEW	0.03	-	-	-	-	-	-	-	-	-	0.03
T209	LTTTGQVTSPVKGAS	-	-	-	-	-	-	-	-	-	-	-
S210	TTTGQVTSPVKGASF	2.2e-15	-	-	1.3e-13	-	7.6e-4	2.2e-9	3.2e-5	5.7e-4	-9.4e-7	0.13
S227	STNPRKFSGFSAKPN	-0.08	-	-	-	-	-0.51	-	6.1e-4	-	-8.4e-4	-3.3e-3
S236	FSAKPNNSGEAPSSP	6.2e-4	-	-	-	-	-	6.2e-4	-	-	-	-
S241	NNSGEAPSSPTPKRS	-	-	-	-	-	-	-	-	-	-	-
S242	NSGEAPSSPTPKRSL	3.9e-5	-	-9.6e-7	6.6e-19	-	0.67	6.5e-11	7.2e-13	0.12	-9.2e-15	-0.78
T317	LLPGVIKTVYNLNDK	0.015	-	-	-	-	3.4e-3	-	-	-	0.6	-
S472	PGQRRALSVQASLMT	-8.4e-7	-	-0.044	-	-	-9.6e-8	-4.7e-5	-0.98	-	0.17	-0.046
S476	RALSVQASLMTPVQP	-	-	-	-	-	-	-	-	-	-	-

Showing 1 to 10 of 18 rows

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* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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			Signed p-values
Phenotype	Site	Meta P	BRCA	CCRCC	COAD	GBM	HNSCC	LSCC	LUAD	OV	PDAC	UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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			Signed p-values
Kinase	Site	Meta P	BRCA	CCRCC	COAD	GBM	HNSCC	LSCC	LUAD	OV	PDAC	UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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			Signed p-values
Phosphatase	Site	Meta P	BRCA	CCRCC	COAD	GBM	HNSCC	LSCC	LUAD	OV	PDAC	UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Protein: ENSP00000367787Gene: LIG3

Lollipop plot

Structure

Phosphosite detection coverage

Tumor and normal comparison

Phenotype and mutation association

Cis-association

Kinase association

Phosphatase association

Protein: ENSP00000367787
Gene: LIG3