Protein: ENSP00000367797
Gene: SKI

LinkedOmicsKB © 2022-2023 Zhang Lab

SKI:
SKI proto-oncogene

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Structure

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S326RRVPRVSSEPPASIR120------------------911
S343TDDTSSQSPAPSEKD963948-62435473-674175693433--516316
S347SSQSPAPSEKDKPSS224----------54------132
S383LSAFRPWSPAVSASE101148105-7556202590-10259989011010120481346414
S394SASEKELSPHLPALI842154-1716--99-10645421311152--7516
S410DSFYSYKSFETAVAP121------------------129
S431PAQQKVVSSPPCAAA346------18-----44----182
S432AQQKVVSSPPCAAAV844138-1210--81-533054492725--833714
T458QPRKRKLTVDTPGAP16------------------6-
T467DTPGAPETLAPVAAP3459---------151344------
Showing 1 to 10 of 14 rows
1025
rows per page

Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S326RRVPRVSSEPPASIR-----------
S343TDDTSSQSPAPSEKD-2.2e-12-3.5e-3---2e-15-5.4e-7-0.15---2.2e-5
S347SSQSPAPSEKDKPSS-----------
S383LSAFRPWSPAVSASE-4.5e-44-3.5e-6-8.9e-8--4.4e-25-3e-21-4.1e-17--5.4e-3-2.8e-7
S394SASEKELSPHLPALI-2.3e-9------3.0e-5----1.9e-5
S410DSFYSYKSFETAVAP-----------
S431PAQQKVVSSPPCAAA-----------
S432AQQKVVSSPPCAAAV-2.4e-26-----6.7e-11-7.2e-7-3.1e-4---7.9e-10
T458QPRKRKLTVDTPGAP-----------
T467DTPGAPETLAPVAAP-----------
Showing 1 to 10 of 14 rows
1025
rows per page

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAS326S343S347S383S394S410S431S432T458T467S480S501S515S720proteinRNASCNVmethylationCCRCCS326S343S347S383S394S410S431S432T458T467S480S501S515S720proteinRNASCNVmethylationCOADS326S343S347S383S394S410S431S432T458T467S480S501S515S720proteinRNASCNVmethylationGBMS326S343S347S383S394S410S431S432T458T467S480S501S515S720proteinRNASCNVmethylationHNSCCS326S343S347S383S394S410S431S432T458T467S480S501S515S720proteinRNASCNVmethylationLSCCS326S343S347S383S394S410S431S432T458T467S480S501S515S720proteinRNASCNVmethylationLUADS326S343S347S383S394S410S431S432T458T467S480S501S515S720proteinRNASCNVmethylationOVS326S343S347S383S394S410S431S432T458T467S480S501S515S720proteinRNASCNVmethylationPDACS326S343S347S383S394S410S431S432T458T467S480S501S515S720proteinRNASCNVmethylationUCECS326S343S347S383S394S410S431S432T458T467S480S501S515S720proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.