Protein: ENSP00000367950
Gene: SHROOM1

LinkedOmicsKB © 2022-2023 Zhang Lab

SHROOM1:
shroom family member 1

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S18ASPASSTSSLDLWHL18--------------71----
S40YSSFSAASGGPEPRT23122-----------------72
S49GPEPRTQSPGTDLLP841614---737981-108108--262847716
T52PRTQSPGTDLLPYLD218--54------54--------
T81PPDAALCTSPRPRPA847477-7352--53-331833302625--321462
S82PDAALCTSPRPRPAV9299--2825272745-535412124292111185
T103QPTEVPGTPGPLNRQ939162-2018141346---4946262334915511-
T112GPLNRQATPLLYALA3157--4535--17-----------4416
S133AQAAEPPSPPASRAA10104221-8969929252-101565755988918340157817
S157RRVLRETSFQRKELR225--98--8-------------
Showing 1 to 10 of 25 rows
1025
rows per page

Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S18ASPASSTSSLDLWHL-----------
S40YSSFSAASGGPEPRT-----------
S49GPEPRTQSPGTDLLP-9.2e-5---0.26-------1.0e-5
T52PRTQSPGTDLLPYLD-----------
T81PPDAALCTSPRPRPA-0.015--3.8e-3---3.7e-4-0.07-0.088-5.5e-6-
S82PDAALCTSPRPRPAV0.054-7.4e-6-0.05-----0.41-
T103QPTEVPGTPGPLNRQ0.022--0.78---0.943.0e-5---
T112GPLNRQATPLLYALA3.2e-4-9.5e-7-------0.85
S133AQAAEPPSPPASRAA-9.4e-3-4.2e-13-0.062--1.7e-12-1.8e-8-2.7e-3-4.3e-4-0.93
S157RRVLRETSFQRKELR-----------
Showing 1 to 10 of 25 rows
1025
rows per page

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAS18S40S49T52T81S82T103T112S133S157S166S188S190S224S250S291S302S304S306S308S314S401S565S735T839proteinRNASCNVmethylationCCRCCS18S40S49T52T81S82T103T112S133S157S166S188S190S224S250S291S302S304S306S308S314S401S565S735T839proteinRNASCNVmethylationCOADS18S40S49T52T81S82T103T112S133S157S166S188S190S224S250S291S302S304S306S308S314S401S565S735T839proteinRNASCNVmethylationGBMS18S40S49T52T81S82T103T112S133S157S166S188S190S224S250S291S302S304S306S308S314S401S565S735T839proteinRNASCNVmethylationHNSCCS18S40S49T52T81S82T103T112S133S157S166S188S190S224S250S291S302S304S306S308S314S401S565S735T839proteinRNASCNVmethylationLSCCS18S40S49T52T81S82T103T112S133S157S166S188S190S224S250S291S302S304S306S308S314S401S565S735T839proteinRNASCNVmethylationLUADS18S40S49T52T81S82T103T112S133S157S166S188S190S224S250S291S302S304S306S308S314S401S565S735T839proteinRNASCNVmethylationOVS18S40S49T52T81S82T103T112S133S157S166S188S190S224S250S291S302S304S306S308S314S401S565S735T839proteinRNASCNVmethylationPDACS18S40S49T52T81S82T103T112S133S157S166S188S190S224S250S291S302S304S306S308S314S401S565S735T839proteinRNASCNVmethylationUCECS18S40S49T52T81S82T103T112S133S157S166S188S190S224S250S291S302S304S306S308S314S401S565S735T839proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.