DVL1: dishevelled segment polarity protein 1
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
6lca chain A
6lca chain B
6lca chain C
6lca chain D
6lca chain E
6lca chain F
6lca chain G
6lca chain H
6lcb chain A
6ttk chain E
6ttk chain F
6ttk chain G
6ttk chain H
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S89 VLAEGAHS DAGSQGT 4 82 7 - 29 28 - - 9 - 6 3 - - - - - - - - - - S93 GAHSDAGS QGTDSHT 5 135 15 - 33 32 - - 17 - 17 12 - - - - - - - - - 9 T96 SDAGSQGT DSHTDLP 1 8 - - 4 4 - - - - - - - - - - - - - - - - S115 RTGGIGDS RPPSFHP 1 8 - - - - - - - - - - - - - - - - - - 6 2 S119 IGDSRPPS FHPNVAS 2 16 - - 4 4 - - - - - - - - - - - - - - 6 2 S126 SFHPNVAS SRDGMDN 1 8 - - - - - - - - - - - - - - 6 2 - - - - S127 FHPNVASS RDGMDNE 1 18 - - - - - - - - - - - - - - 15 3 - - - - T135 RDGMDNET GTESMVS 1 9 - - - - - - - - - - - - - - 7 2 - - - - S184 SASTALSS ELESSSF 2 16 8 - - - - - - - 5 3 - - - - - - - - - - S194 ESSSFVDS DEDGSTS 9 322 23 - - - 4 5 71 - 12 6 34 31 26 24 12 1 4 2 49 18
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S89 VLAEGAHS DAGSQGT -0.72 - -0.72 - - - - - - - - S93 GAHSDAGS QGTDSHT -0.33 - -0.33 - - - - - - - - T96 SDAGSQGT DSHTDLP - - - - - - - - - - - S115 RTGGIGDS RPPSFHP - - - - - - - - - - - S119 IGDSRPPS FHPNVAS - - - - - - - - - - - S126 SFHPNVAS SRDGMDN - - - - - - - - - - - S127 FHPNVASS RDGMDNE - - - - - - - - - - - T135 RDGMDNET GTESMVS - - - - - - - - - - - S184 SASTALSS ELESSSF - - - - - - - - - - - S194 ESSSFVDS DEDGSTS -0.37 - - - - - -0.13 -0.29 - - 0.31
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S89
S93
T96
S115
S119
S126
S127
T135
S184
S194
S204
S205
S380
S390
T395
S600
S602
S604
S625
T648
T674
S676
S679
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S89 S93 T96 S115 S119 S126 S127 T135 S184 S194 S204 S205 S380 S390 T395 S600 S602 S604 S625 T648 T674 S676 S679 protein RNA SCNV methylation CCRCC S89 S93 T96 S115 S119 S126 S127 T135 S184 S194 S204 S205 S380 S390 T395 S600 S602 S604 S625 T648 T674 S676 S679 protein RNA SCNV methylation COAD S89 S93 T96 S115 S119 S126 S127 T135 S184 S194 S204 S205 S380 S390 T395 S600 S602 S604 S625 T648 T674 S676 S679 protein RNA SCNV methylation GBM S89 S93 T96 S115 S119 S126 S127 T135 S184 S194 S204 S205 S380 S390 T395 S600 S602 S604 S625 T648 T674 S676 S679 protein RNA SCNV methylation HNSCC S89 S93 T96 S115 S119 S126 S127 T135 S184 S194 S204 S205 S380 S390 T395 S600 S602 S604 S625 T648 T674 S676 S679 protein RNA SCNV methylation LSCC S89 S93 T96 S115 S119 S126 S127 T135 S184 S194 S204 S205 S380 S390 T395 S600 S602 S604 S625 T648 T674 S676 S679 protein RNA SCNV methylation LUAD S89 S93 T96 S115 S119 S126 S127 T135 S184 S194 S204 S205 S380 S390 T395 S600 S602 S604 S625 T648 T674 S676 S679 protein RNA SCNV methylation OV S89 S93 T96 S115 S119 S126 S127 T135 S184 S194 S204 S205 S380 S390 T395 S600 S602 S604 S625 T648 T674 S676 S679 protein RNA SCNV methylation PDAC S89 S93 T96 S115 S119 S126 S127 T135 S184 S194 S204 S205 S380 S390 T395 S600 S602 S604 S625 T648 T674 S676 S679 protein RNA SCNV methylation UCEC S89 S93 T96 S115 S119 S126 S127 T135 S184 S194 S204 S205 S380 S390 T395 S600 S602 S604 S625 T648 T674 S676 S679 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S89
S93
T96
S115
S119
S126
S127
T135
S184
S194
S204
S205
S380
S390
T395
S600
S602
S604
S625
T648
T674
S676
S679
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S89
S93
T96
S115
S119
S126
S127
T135
S184
S194
S204
S205
S380
S390
T395
S600
S602
S604
S625
T648
T674
S676
S679
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.