Protein: ENSP00000368570

TNFRSF18:: TNF receptor superfamily member 18

Lollipop plot

Phosphosites location and occurrence

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* Hover over the dots to see sequence motif and cohorts.

Structure

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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				BRCA		CCRCC		COAD		GBM		HNSCC		LSCC		LUAD		OV		PDAC		UCEC
Site	Sequence	Cohorts	Total	T	N	T	N	T	N	T	N	T	N	T	N	T	N	T	N	T	N	T	N
S217	PSTEDARSCQFPEEE	3	47	-	-	-	-	-	-	-	-	5	4	15	14	-	-	-	-	-	-	7	2

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Tumor and normal comparison

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Site	Sequence	Meta P	BRCA	CCRCC	COAD	GBM	HNSCC	LSCC	LUAD	OV	PDAC	UCEC
S217	PSTEDARSCQFPEEE	-	-	-	-	-	-	-	-	-	-	-

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* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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			Signed p-values
Phenotype	Site	Meta P	BRCA	CCRCC	COAD	GBM	HNSCC	LSCC	LUAD	OV	PDAC	UCEC
cibersort: T cell CD4+ memory activated	S217	9.1e-4	-	-	-	-	-	9.1e-4	-	-	-	-
xcell: Myeloid dendritic cell activated	S217	6.9e-3	-	-	-	-	-	6.9e-3	-	-	-	-
xcell: T cell CD8+ naive	S217	0.011	-	-	-	-	-	0.011	-	-	-	-
Clinical: Tumor_Size_cm	S217	0.045	-	-	-	-	-	0.045	-	-	-	-
xcell: T cell CD8+ effector memory	S217	0.045	-	-	-	-	-	0.045	-	-	-	-
xcell: B cell plasma	S217	0.06	-	-	-	-	-	0.06	-	-	-	-
cibersort: Macrophage M1	S217	0.067	-	-	-	-	-	0.067	-	-	-	-
xcell: Plasmacytoid dendritic cell	S217	0.078	-	-	-	-	-	0.078	-	-	-	-
cibersort: B cell plasma	S217	0.083	-	-	-	-	-	0.083	-	-	-	-
xcell: T cell CD4+ effector memory	S217	0.086	-	-	-	-	-	0.085	-	-	-	-

Showing 1 to 10 of 258 rows

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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			Signed p-values
Kinase	Site	Meta P	BRCA	CCRCC	COAD	GBM	HNSCC	LSCC	LUAD	OV	PDAC	UCEC
LIMK1	S217	2.9e-3	-	-	-	-	-	2.9e-3	-	-	-	-
TBK1	S217	2.9e-3	-	-	-	-	-	2.9e-3	-	-	-	-
MAP2K7	S217	4.6e-3	-	-	-	-	-	4.6e-3	-	-	-	-
MAP2K4	S217	8.6e-3	-	-	-	-	-	8.6e-3	-	-	-	-
LCK	S217	0.025	-	-	-	-	-	0.025	-	-	-	-
MAP2K2	S217	0.025	-	-	-	-	-	0.025	-	-	-	-
FYN	S217	0.034	-	-	-	-	-	0.034	-	-	-	-
PDK1	S217	0.035	-	-	-	-	-	0.035	-	-	-	-
ITK	S217	0.041	-	-	-	-	-	0.041	-	-	-	-
MAP2K1	S217	0.049	-	-	-	-	-	0.049	-	-	-	-

Showing 1 to 10 of 538 rows

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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			Signed p-values
Phosphatase	Site	Meta P	BRCA	CCRCC	COAD	GBM	HNSCC	LSCC	LUAD	OV	PDAC	UCEC
MTMR2	S217	-1.3e-3	-	-	-	-	-	-1.3e-3	-	-	-	-
ACP6	S217	-0.012	-	-	-	-	-	-0.012	-	-	-	-
PTPN3	S217	-0.023	-	-	-	-	-	-0.023	-	-	-	-
MINPP1	S217	-0.051	-	-	-	-	-	-0.051	-	-	-	-
SGPP2	S217	-0.11	-	-	-	-	-	-0.11	-	-	-	-
PTPRG	S217	-0.11	-	-	-	-	-	-0.11	-	-	-	-
DUSP19	S217	-0.11	-	-	-	-	-	-0.11	-	-	-	-
PTPRB	S217	-0.13	-	-	-	-	-	-0.13	-	-	-	-
TNS2	S217	-0.14	-	-	-	-	-	-0.14	-	-	-	-
DUSP1	S217	-0.15	-	-	-	-	-	-0.15	-	-	-	-

Showing 1 to 10 of 240 rows

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Protein: ENSP00000368570Gene: TNFRSF18

Lollipop plot

Structure

Phosphosite detection coverage

Tumor and normal comparison

Phenotype and mutation association

Cis-association

Kinase association

Phosphatase association

Protein: ENSP00000368570
Gene: TNFRSF18