- EDN1:
- endothelin 1
Lollipop plot
Phosphosites location and occurrence
Structure
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
BRCA | CCRCC | COAD | GBM | HNSCC | LSCC | LUAD | OV | PDAC | UCEC | ||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Site
| Sequence | Cohorts | Total | T | N | T | N | T | N | T | N | T | N | T | N | T | N | T | N | T | N | T | N |
| S169 | RGRKIRRSSEEHLRQ | 1 | 39 | - | - | 21 | 18 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
| S170 | GRKIRRSSEEHLRQT | 1 | 16 | - | - | 12 | 4 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
Tumor and normal comparison
Site
| Sequence | Meta P | BRCA | CCRCC | COAD | GBM | HNSCC | LSCC | LUAD | OV | PDAC | UCEC |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| S169 | RGRKIRRSSEEHLRQ | 0.011 | - | 0.011 | - | - | - | - | - | - | - | - |
| S170 | GRKIRRSSEEHLRQT | - | - | - | - | - | - | - | - | - | - | - |
Phenotype and mutation association
Signed p-values | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Phenotype | Site | Meta P | BRCA | CCRCC | COAD | GBM | HNSCC | LSCC | LUAD | OV | PDAC | UCEC |
| xcell: stroma score | S169 | 7.3e-3 | - | 7.3e-3 | - | - | - | - | - | - | - | - |
| cibersort: T cell regulatory (Tregs) | S170 | 8.8e-3 | - | 8.8e-3 | - | - | - | - | - | - | - | - |
| Tumor Purity (WGS) | S169 | 9.2e-3 | - | 9.2e-3 | - | - | - | - | - | - | - | - |
| xcell: Endothelial cell | S169 | 0.011 | - | 0.011 | - | - | - | - | - | - | - | - |
| xcell: Hematopoietic stem cell | S169 | 0.02 | - | 0.02 | - | - | - | - | - | - | - | - |
| Clinical: overall_survival | S169 | 0.078 | - | 0.078 | - | - | - | - | - | - | - | - |
| SBS42 (haloalkane exposure) | S170 | 0.082 | - | 0.082 | - | - | - | - | - | - | - | - |
| xcell: Granulocyte-monocyte progenitor | S170 | 0.087 | - | 0.087 | - | - | - | - | - | - | - | - |
| cibersort: Macrophage M1 | S170 | 0.094 | - | 0.094 | - | - | - | - | - | - | - | - |
| HALLMARK_PANCREAS_BETA_CELLS | S170 | 0.1 | - | 0.1 | - | - | - | - | - | - | - | - |
Cis-association
Kinase association
Signed p-values | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Kinase | Site | Meta P | BRCA | CCRCC | COAD | GBM | HNSCC | LSCC | LUAD | OV | PDAC | UCEC |
| No matching records found | ||||||||||||
Phosphatase association
Signed p-values | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Phosphatase | Site | Meta P | BRCA | CCRCC | COAD | GBM | HNSCC | LSCC | LUAD | OV | PDAC | UCEC |
| PGAM5 | S169 | -4.2e-3 | - | -4.2e-3 | - | - | - | - | - | - | - | - |
| PFKFB3 | S169 | -4.7e-3 | - | -4.7e-3 | - | - | - | - | - | - | - | - |
| PPM1H | S169 | -5.6e-3 | - | -5.6e-3 | - | - | - | - | - | - | - | - |
| PTPRJ | S169 | -5.7e-3 | - | -5.7e-3 | - | - | - | - | - | - | - | - |
| PTPN7 | S169 | -6.3e-3 | - | -6.3e-3 | - | - | - | - | - | - | - | - |
| PFKFB2 | S169 | -0.013 | - | -0.013 | - | - | - | - | - | - | - | - |
| NANP | S170 | -0.013 | - | -0.013 | - | - | - | - | - | - | - | - |
| DNAJC6 | S169 | -0.014 | - | -0.014 | - | - | - | - | - | - | - | - |
| INPP4A | S169 | -0.029 | - | -0.029 | - | - | - | - | - | - | - | - |
| PTPN1 | S169 | -0.031 | - | -0.031 | - | - | - | - | - | - | - | - |