TEK: TEK receptor tyrosine kinase
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
1fvr chain A
1fvr chain B
2gy5 chain A
2gy7 chain B
2oo8 chain X
2osc chain A
2p4i chain A
2p4i chain B
2wqb chain A
3bea chain A
3l8p chain A
4k0v chain A
4x3j chain A
5mya chain A
5mya chain B
5myb chain A
5myb chain B
5utk chain A
5utk chain B
6mwe chain A
6mwe chain B
7e72 chain E
7e72 chain F
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S1119 TYAGIDCS AEEAA__ 5 512 - - 37 32 - - - - 17 8 98 90 97 89 - - - - 31 13
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S1119 TYAGIDCS AEEAA__ -5.5e-38 - -6.0e-4 - - - -5.5e-27 -3.4e-24 - - -0.15
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S1119
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S1119 protein RNA SCNV methylation CCRCC S1119 protein RNA SCNV methylation COAD S1119 protein RNA SCNV methylation GBM S1119 protein RNA SCNV methylation HNSCC S1119 protein RNA SCNV methylation LSCC S1119 protein RNA SCNV methylation LUAD S1119 protein RNA SCNV methylation OV S1119 protein RNA SCNV methylation PDAC S1119 protein RNA SCNV methylation UCEC S1119 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S1119
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S1119
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.