SLTM: SAFB like transcription modulator
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T69 DPDNIELT VSTDTPN 4 43 9 - - - - - - - - - 10 10 4 4 - - 5 1 - - T74 ELTVSTDT PNKKPTK 2 39 - - - - - - - - - - - - 9 8 - - - - 18 4 S93 KHEADELS GDASVED 7 291 47 - 22 20 - - 45 - 46 26 24 23 4 4 - - - - 19 11 S97 DELSGDAS VEDDAFI 7 642 53 - 58 47 - - 62 - 92 54 39 35 70 64 - - 49 19 - - S126 GNDELKDS EEFGENE 8 795 113 - 10 8 - - 90 - 77 39 108 99 65 57 - - 51 21 44 13 S139 NEEENVHS KELLSAE 5 210 - - - - - - 19 - 12 5 43 41 37 32 - - - - 17 4 S144 VHSKELLS AEENKRA 10 796 80 - 47 26 11 7 62 - 90 51 93 86 31 29 12 4 75 32 42 18 S170 IEKEDIES QEIEAQE 8 915 47 - 80 65 - - 81 - 108 62 68 61 76 64 - - 68 28 89 18 T182 AQEGEDDT FLTAQDG 3 33 - - - - - - - - 7 2 10 8 - - - - - - 6 - T185 GEDDTFLT AQDGEEE 4 42 - - 4 4 - - - - 5 3 10 8 4 4 - - - - - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
T69 DPDNIELT VSTDTPN - - - - - - - - - - - T74 ELTVSTDT PNKKPTK - - - - - - - - - - - S93 KHEADELS GDASVED 2.9e-5 - -0.72 - - 5.2e-3 1.5e-6 - - - - S97 DELSGDAS VEDDAFI 1e-14 - 0.69 - - 5.3e-3 1.2e-12 1.7e-10 - 0.54 - S126 GNDELKDS EEFGENE 3.2e-57 - - - - 9.4e-10 4.3e-29 1.7e-14 - 7.1e-8 1.3e-7 S139 NEEENVHS KELLSAE 3.1e-12 - - - - - 1.5e-8 2.6e-5 - - - S144 VHSKELLS AEENKRA 0.38 - 0.25 - - 4.8e-3 0.66 1.6e-5 - -3.7e-5 -0.014 S170 IEKEDIES QEIEAQE 1.2e-47 - 3.7e-3 - - 2.2e-11 1.8e-19 1.7e-19 - 2.8e-5 2.2e-4 T182 AQEGEDDT FLTAQDG - - - - - - - - - - - T185 GEDDTFLT AQDGEEE - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
T69
T74
S93
S97
S126
S139
S144
S170
T182
T185
S201
T205
S214
S217
S277
S289
S294
S343
S344
T345
S348
S371
T372
S373
S374
T375
S421
S533
S537
S539
S543
S550
S551
S553
S590
S748
S759
S788
S789
S815
T881
S882
S885
S888
S890
S909
S912
S922
S923
S929
T938
S944
T995
S998
S999
S1002
S1014
S1019
S1021
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA T69 T74 S93 S97 S126 S139 S144 S170 T182 T185 S201 T205 S214 S217 S277 S289 S294 S343 S344 T345 S348 S371 T372 S373 S374 T375 S421 S533 S537 S539 S543 S550 S551 S553 S590 S748 S759 S788 S789 S815 T881 S882 S885 S888 S890 S909 S912 S922 S923 S929 T938 S944 T995 S998 S999 S1002 S1014 S1019 S1021 protein RNA SCNV methylation CCRCC T69 T74 S93 S97 S126 S139 S144 S170 T182 T185 S201 T205 S214 S217 S277 S289 S294 S343 S344 T345 S348 S371 T372 S373 S374 T375 S421 S533 S537 S539 S543 S550 S551 S553 S590 S748 S759 S788 S789 S815 T881 S882 S885 S888 S890 S909 S912 S922 S923 S929 T938 S944 T995 S998 S999 S1002 S1014 S1019 S1021 protein RNA SCNV methylation COAD T69 T74 S93 S97 S126 S139 S144 S170 T182 T185 S201 T205 S214 S217 S277 S289 S294 S343 S344 T345 S348 S371 T372 S373 S374 T375 S421 S533 S537 S539 S543 S550 S551 S553 S590 S748 S759 S788 S789 S815 T881 S882 S885 S888 S890 S909 S912 S922 S923 S929 T938 S944 T995 S998 S999 S1002 S1014 S1019 S1021 protein RNA SCNV methylation GBM T69 T74 S93 S97 S126 S139 S144 S170 T182 T185 S201 T205 S214 S217 S277 S289 S294 S343 S344 T345 S348 S371 T372 S373 S374 T375 S421 S533 S537 S539 S543 S550 S551 S553 S590 S748 S759 S788 S789 S815 T881 S882 S885 S888 S890 S909 S912 S922 S923 S929 T938 S944 T995 S998 S999 S1002 S1014 S1019 S1021 protein RNA SCNV methylation HNSCC T69 T74 S93 S97 S126 S139 S144 S170 T182 T185 S201 T205 S214 S217 S277 S289 S294 S343 S344 T345 S348 S371 T372 S373 S374 T375 S421 S533 S537 S539 S543 S550 S551 S553 S590 S748 S759 S788 S789 S815 T881 S882 S885 S888 S890 S909 S912 S922 S923 S929 T938 S944 T995 S998 S999 S1002 S1014 S1019 S1021 protein RNA SCNV methylation LSCC T69 T74 S93 S97 S126 S139 S144 S170 T182 T185 S201 T205 S214 S217 S277 S289 S294 S343 S344 T345 S348 S371 T372 S373 S374 T375 S421 S533 S537 S539 S543 S550 S551 S553 S590 S748 S759 S788 S789 S815 T881 S882 S885 S888 S890 S909 S912 S922 S923 S929 T938 S944 T995 S998 S999 S1002 S1014 S1019 S1021 protein RNA SCNV methylation LUAD T69 T74 S93 S97 S126 S139 S144 S170 T182 T185 S201 T205 S214 S217 S277 S289 S294 S343 S344 T345 S348 S371 T372 S373 S374 T375 S421 S533 S537 S539 S543 S550 S551 S553 S590 S748 S759 S788 S789 S815 T881 S882 S885 S888 S890 S909 S912 S922 S923 S929 T938 S944 T995 S998 S999 S1002 S1014 S1019 S1021 protein RNA SCNV methylation OV T69 T74 S93 S97 S126 S139 S144 S170 T182 T185 S201 T205 S214 S217 S277 S289 S294 S343 S344 T345 S348 S371 T372 S373 S374 T375 S421 S533 S537 S539 S543 S550 S551 S553 S590 S748 S759 S788 S789 S815 T881 S882 S885 S888 S890 S909 S912 S922 S923 S929 T938 S944 T995 S998 S999 S1002 S1014 S1019 S1021 protein RNA SCNV methylation PDAC T69 T74 S93 S97 S126 S139 S144 S170 T182 T185 S201 T205 S214 S217 S277 S289 S294 S343 S344 T345 S348 S371 T372 S373 S374 T375 S421 S533 S537 S539 S543 S550 S551 S553 S590 S748 S759 S788 S789 S815 T881 S882 S885 S888 S890 S909 S912 S922 S923 S929 T938 S944 T995 S998 S999 S1002 S1014 S1019 S1021 protein RNA SCNV methylation UCEC T69 T74 S93 S97 S126 S139 S144 S170 T182 T185 S201 T205 S214 S217 S277 S289 S294 S343 S344 T345 S348 S371 T372 S373 S374 T375 S421 S533 S537 S539 S543 S550 S551 S553 S590 S748 S759 S788 S789 S815 T881 S882 S885 S888 S890 S909 S912 S922 S923 S929 T938 S944 T995 S998 S999 S1002 S1014 S1019 S1021 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
T69
T74
S93
S97
S126
S139
S144
S170
T182
T185
S201
T205
S214
S217
S277
S289
S294
S343
S344
T345
S348
S371
T372
S373
S374
T375
S421
S533
S537
S539
S543
S550
S551
S553
S590
S748
S759
S788
S789
S815
T881
S882
S885
S888
S890
S909
S912
S922
S923
S929
T938
S944
T995
S998
S999
S1002
S1014
S1019
S1021
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
T69
T74
S93
S97
S126
S139
S144
S170
T182
T185
S201
T205
S214
S217
S277
S289
S294
S343
S344
T345
S348
S371
T372
S373
S374
T375
S421
S533
S537
S539
S543
S550
S551
S553
S590
S748
S759
S788
S789
S815
T881
S882
S885
S888
S890
S909
S912
S922
S923
S929
T938
S944
T995
S998
S999
S1002
S1014
S1019
S1021
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.