- GEMIN8:
- gem nuclear organelle associated protein 8
Lollipop plot
Phosphosites location and occurrence
Structure
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
BRCA | CCRCC | COAD | GBM | HNSCC | LSCC | LUAD | OV | PDAC | UCEC | ||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Site
| Sequence | Cohorts | Total | T | N | T | N | T | N | T | N | T | N | T | N | T | N | T | N | T | N | T | N |
S117 | TKEDQALSKEEEMET | 8 | 991 | 88 | - | 68 | 59 | - | - | 37 | - | 95 | 55 | 98 | 89 | 101 | 93 | - | - | 97 | 40 | 53 | 18 |
T124 | SKEEEMETESDAEVE | 8 | 641 | 96 | - | 37 | 28 | 47 | 42 | - | - | 12 | 7 | 88 | 77 | 61 | 56 | - | - | 3 | 2 | 67 | 18 |
S126 | EEEMETESDAEVECD | 8 | 612 | 81 | - | 54 | 34 | 7 | 2 | - | - | 72 | 39 | 78 | 70 | 48 | 45 | - | - | 3 | 2 | 61 | 16 |
S135 | AEVECDLSNMEITEE | 2 | 19 | - | - | - | - | - | - | - | - | 5 | 4 | 5 | 5 | - | - | - | - | - | - | - | - |
S185 | LYCNTRRSVEAPTER | 7 | 471 | - | - | - | - | 46 | 43 | - | - | 74 | 42 | 30 | 28 | 22 | 20 | 63 | 14 | 56 | 24 | 7 | 2 |
Tumor and normal comparison
Site
| Sequence | Meta P | BRCA | CCRCC | COAD | GBM | HNSCC | LSCC | LUAD | OV | PDAC | UCEC |
---|---|---|---|---|---|---|---|---|---|---|---|---|
S117 | TKEDQALSKEEEMET | 5.4e-14 | - | 0.074 | - | - | 0.73 | 1.7e-16 | 2.9e-14 | - | -0.072 | 0.025 |
T124 | SKEEEMETESDAEVE | 3.9e-6 | - | -0.014 | 0.13 | - | - | 3.5e-10 | 1.3e-3 | - | - | 0.075 |
S126 | EEEMETESDAEVECD | -0.6 | - | -1.7e-4 | - | - | 0.013 | 4.4e-5 | -3.2e-3 | - | - | -0.31 |
S135 | AEVECDLSNMEITEE | - | - | - | - | - | - | - | - | - | - | - |
S185 | LYCNTRRSVEAPTER | 2.9e-4 | - | - | 6.5e-11 | - | 2.4e-4 | 0.43 | 0.14 | 0.23 | -1.5e-6 | - |
Phenotype and mutation association
Signed p-values | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Phenotype | Site | Meta P | BRCA | CCRCC | COAD | GBM | HNSCC | LSCC | LUAD | OV | PDAC | UCEC |
No matching records found |
Cis-association
Kinase association
Signed p-values | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Kinase | Site | Meta P | BRCA | CCRCC | COAD | GBM | HNSCC | LSCC | LUAD | OV | PDAC | UCEC |
No matching records found |
Phosphatase association
Signed p-values | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Phosphatase | Site | Meta P | BRCA | CCRCC | COAD | GBM | HNSCC | LSCC | LUAD | OV | PDAC | UCEC |
No matching records found |