PSIP1: PC4 and SFRS1 interacting protein 1
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
1z9e chain A
2b4j chain C
2b4j chain D
2m16 chain A
2msr chain B
2mtn chain A
2n3a chain B
3f9k chain C
3f9k chain G
3f9k chain K
3f9k chain O
3f9k chain S
3f9k chain W
3f9k chain a
3f9k chain e
3f9k chain i
3f9k chain m
3f9k chain q
3f9k chain u
3hpg chain G
3hpg chain H
3hpg chain I
3hpg chain J
3hpg chain K
3hpg chain L
3hph chain E
3hph chain F
3hph chain G
3hph chain H
3u88 chain C
3u88 chain D
3zeh chain A
4fu6 chain A
5n88 chain D
5n88 chain E
5oym chain A
5oym chain B
5oym chain C
5oym chain D
5oym chain E
5oym chain F
5oym chain G
5oym chain H
5yi9 chain A
6emo chain A
6emp chain A
6emq chain A
6emr chain A
6s01 chain K
6trj chain A
6tvm chain A
6tvm chain B
6zv0 chain A
7z1z chain Q
7z1z chain R
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S94 NPKVKFSS QQAATKQ 3 69 - - - - - - 18 - - - 5 5 - - - - - - 36 5 S102 QQAATKQS NASSDVE 7 686 - - 91 68 - - 90 - 23 11 83 75 97 90 - - 9 2 42 5 S105 ATKQSNAS SDVEVEE 6 187 - - 11 11 - - 90 - 13 5 9 9 18 15 - - - - 6 - S106 TKQSNASS DVEVEEK 7 1096 - - 103 80 - - 99 - 108 62 98 91 101 93 - - 105 43 95 18 T115 VEVEEKET SVSKEDT 2 32 - - 12 12 - - - - - - 4 4 - - - - - - - - S116 EVEEKETS VSKEDTD 7 370 - - 8 8 - - 90 - 23 12 25 22 9 9 - - 59 24 74 7 S118 EEKETSVS KEDTDHE 6 522 - - - - - - 64 - 24 12 108 99 101 93 - - 9 4 6 2 T122 TSVSKEDT DHEEKAS 7 1053 - - 91 76 - - 99 - 85 49 108 99 106 97 - - 105 44 76 18 S129 TDHEEKAS NEDVTKA 7 1122 - - 103 80 - - 99 - 101 59 108 99 110 101 - - 105 44 95 18 T140 VTKAVDIT TPKAARR 1 8 - - - - - - - - - - - - 4 4 - - - - - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S94 NPKVKFSS QQAATKQ - - - - - - - - - - - S102 QQAATKQS NASSDVE -3e-16 - 0.35 - - -0.56 -7.6e-12 -7.3e-23 - - - S105 ATKQSNAS SDVEVEE - - - - - - - - - - - S106 TKQSNASS DVEVEEK -9.6e-21 - 0.97 - - -0.029 -0.025 -6.3e-11 - -9.4e-17 -2.6e-4 T115 VEVEEKET SVSKEDT - - - - - - - - - - - S116 EVEEKETS VSKEDTD 0.11 - - - - 0.82 0.011 - - -0.96 - S118 EEKETSVS KEDTDHE -3.5e-6 - - - - -0.16 0.38 -6.5e-14 - - - T122 TSVSKEDT DHEEKAS -7.1e-7 - -9.4e-6 - - 1.6e-3 -0.018 -2e-9 - 0.075 -1.8e-5 S129 TDHEEKAS NEDVTKA -9.7e-25 - -8.1e-3 - - -2.8e-8 -3.7e-7 -9.4e-22 - 0.28 -7.3e-4 T140 VTKAVDIT TPKAARR - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S94
S102
S105
S106
T115
S116
S118
T122
S129
T140
T141
T167
S171
S177
S206
S208
S271
T272
S273
S275
S347
S482
S496
S500
S513
S514
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S94 S102 S105 S106 T115 S116 S118 T122 S129 T140 T141 T167 S171 S177 S206 S208 S271 T272 S273 S275 S347 S482 S496 S500 S513 S514 protein RNA SCNV methylation CCRCC S94 S102 S105 S106 T115 S116 S118 T122 S129 T140 T141 T167 S171 S177 S206 S208 S271 T272 S273 S275 S347 S482 S496 S500 S513 S514 protein RNA SCNV methylation COAD S94 S102 S105 S106 T115 S116 S118 T122 S129 T140 T141 T167 S171 S177 S206 S208 S271 T272 S273 S275 S347 S482 S496 S500 S513 S514 protein RNA SCNV methylation GBM S94 S102 S105 S106 T115 S116 S118 T122 S129 T140 T141 T167 S171 S177 S206 S208 S271 T272 S273 S275 S347 S482 S496 S500 S513 S514 protein RNA SCNV methylation HNSCC S94 S102 S105 S106 T115 S116 S118 T122 S129 T140 T141 T167 S171 S177 S206 S208 S271 T272 S273 S275 S347 S482 S496 S500 S513 S514 protein RNA SCNV methylation LSCC S94 S102 S105 S106 T115 S116 S118 T122 S129 T140 T141 T167 S171 S177 S206 S208 S271 T272 S273 S275 S347 S482 S496 S500 S513 S514 protein RNA SCNV methylation LUAD S94 S102 S105 S106 T115 S116 S118 T122 S129 T140 T141 T167 S171 S177 S206 S208 S271 T272 S273 S275 S347 S482 S496 S500 S513 S514 protein RNA SCNV methylation OV S94 S102 S105 S106 T115 S116 S118 T122 S129 T140 T141 T167 S171 S177 S206 S208 S271 T272 S273 S275 S347 S482 S496 S500 S513 S514 protein RNA SCNV methylation PDAC S94 S102 S105 S106 T115 S116 S118 T122 S129 T140 T141 T167 S171 S177 S206 S208 S271 T272 S273 S275 S347 S482 S496 S500 S513 S514 protein RNA SCNV methylation UCEC S94 S102 S105 S106 T115 S116 S118 T122 S129 T140 T141 T167 S171 S177 S206 S208 S271 T272 S273 S275 S347 S482 S496 S500 S513 S514 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S94
S102
S105
S106
T115
S116
S118
T122
S129
T140
T141
T167
S171
S177
S206
S208
S271
T272
S273
S275
S347
S482
S496
S500
S513
S514
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S94
S102
S105
S106
T115
S116
S118
T122
S129
T140
T141
T167
S171
S177
S206
S208
S271
T272
S273
S275
S347
S482
S496
S500
S513
S514
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.