Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
1ki1 chain B
1ki1 chain D
2kgr chain A
2khn chain A
3fia chain A
3qbv chain B
3qbv chain D
4iim chain A
4iim chain B
5hzi chain A
5hzi chain B
5hzj chain A
5hzj chain B
5hzk chain B
5hzk chain D
6gbu chain B
6gbu chain D
6gbu chain F
6gbu chain H
6h5t chain A
6h5t chain B
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S188 KSSSFSRS GPGSQLN 3 90 - - - - - - - - - - 30 26 9 9 - - 12 4 - - S192 FSRSGPGS QLNTKLQ 7 448 - - 36 33 - - 28 - 12 6 48 44 96 89 - - 26 10 18 2 S203 TKLQKAQS FDVASVP 7 1128 - - 103 80 - - 99 - 108 62 105 98 110 101 - - 105 44 95 18 S208 AQSFDVAS VPPVAEW 1 9 - - - - - - - - - - - - 5 4 - - - - - - S313 PSFRRVRS GSGISVI 6 178 - - 14 12 - - 9 - - - 39 37 9 8 - - 27 10 13 - S315 FRRVRSGS GISVISS 7 745 - - 99 76 - - 82 - 58 33 50 45 61 57 - - 63 25 78 18 S318 VRSGSGIS VISSTSV 2 15 - - - - - - - - - - 5 4 - - - - - - 6 - S321 GSGISVIS STSVDQR 1 14 - - - - - - - - - - - - - - - - - - 11 3 T323 GISVISST SVDQRLP 1 8 - - - - - - - - - - - - 4 4 - - - - - - S324 ISVISSTS VDQRLPE 6 221 - - 5 4 - - 62 - 5 3 39 35 21 21 - - - - 13 13
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S188 KSSSFSRS GPGSQLN 0.5 - - - - - 0.5 - - - - S192 FSRSGPGS QLNTKLQ -0.031 - -0.019 - - - -2.3e-6 0.61 - 0.026 - S203 TKLQKAQS FDVASVP -9.9e-6 - 0.15 - - -7.9e-4 -3.8e-18 -0.54 - 8.2e-6 -4.6e-5 S208 AQSFDVAS VPPVAEW - - - - - - - - - - - S313 PSFRRVRS GSGISVI -0.99 - - - - - 0.05 - - -0.048 - S315 FRRVRSGS GISVISS -8e-7 - 0.38 - - -3.4e-6 -2.4e-3 -0.15 - -0.37 -3.2e-3 S318 VRSGSGIS VISSTSV - - - - - - - - - - - S321 GSGISVIS STSVDQR - - - - - - - - - - - T323 GISVISST SVDQRLP - - - - - - - - - - - S324 ISVISSTS VDQRLPE -3.7e-5 - - - - - -5.6e-8 -0.69 - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S188
S192
S203
S208
S313
S315
S318
S321
T323
S324
S559
S564
T567
S624
S687
S891
T894
S901
S902
S904
S976
T977
S978
S981
S983
S984
S986
S989
S995
S1071
S1137
T1144
T1146
S1627
S1645
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S188 S192 S203 S208 S313 S315 S318 S321 T323 S324 S559 S564 T567 S624 S687 S891 T894 S901 S902 S904 S976 T977 S978 S981 S983 S984 S986 S989 S995 S1071 S1137 T1144 T1146 S1627 S1645 protein RNA SCNV methylation CCRCC S188 S192 S203 S208 S313 S315 S318 S321 T323 S324 S559 S564 T567 S624 S687 S891 T894 S901 S902 S904 S976 T977 S978 S981 S983 S984 S986 S989 S995 S1071 S1137 T1144 T1146 S1627 S1645 protein RNA SCNV methylation COAD S188 S192 S203 S208 S313 S315 S318 S321 T323 S324 S559 S564 T567 S624 S687 S891 T894 S901 S902 S904 S976 T977 S978 S981 S983 S984 S986 S989 S995 S1071 S1137 T1144 T1146 S1627 S1645 protein RNA SCNV methylation GBM S188 S192 S203 S208 S313 S315 S318 S321 T323 S324 S559 S564 T567 S624 S687 S891 T894 S901 S902 S904 S976 T977 S978 S981 S983 S984 S986 S989 S995 S1071 S1137 T1144 T1146 S1627 S1645 protein RNA SCNV methylation HNSCC S188 S192 S203 S208 S313 S315 S318 S321 T323 S324 S559 S564 T567 S624 S687 S891 T894 S901 S902 S904 S976 T977 S978 S981 S983 S984 S986 S989 S995 S1071 S1137 T1144 T1146 S1627 S1645 protein RNA SCNV methylation LSCC S188 S192 S203 S208 S313 S315 S318 S321 T323 S324 S559 S564 T567 S624 S687 S891 T894 S901 S902 S904 S976 T977 S978 S981 S983 S984 S986 S989 S995 S1071 S1137 T1144 T1146 S1627 S1645 protein RNA SCNV methylation LUAD S188 S192 S203 S208 S313 S315 S318 S321 T323 S324 S559 S564 T567 S624 S687 S891 T894 S901 S902 S904 S976 T977 S978 S981 S983 S984 S986 S989 S995 S1071 S1137 T1144 T1146 S1627 S1645 protein RNA SCNV methylation OV S188 S192 S203 S208 S313 S315 S318 S321 T323 S324 S559 S564 T567 S624 S687 S891 T894 S901 S902 S904 S976 T977 S978 S981 S983 S984 S986 S989 S995 S1071 S1137 T1144 T1146 S1627 S1645 protein RNA SCNV methylation PDAC S188 S192 S203 S208 S313 S315 S318 S321 T323 S324 S559 S564 T567 S624 S687 S891 T894 S901 S902 S904 S976 T977 S978 S981 S983 S984 S986 S989 S995 S1071 S1137 T1144 T1146 S1627 S1645 protein RNA SCNV methylation UCEC S188 S192 S203 S208 S313 S315 S318 S321 T323 S324 S559 S564 T567 S624 S687 S891 T894 S901 S902 S904 S976 T977 S978 S981 S983 S984 S986 S989 S995 S1071 S1137 T1144 T1146 S1627 S1645 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S188
S192
S203
S208
S313
S315
S318
S321
T323
S324
S559
S564
T567
S624
S687
S891
T894
S901
S902
S904
S976
T977
S978
S981
S983
S984
S986
S989
S995
S1071
S1137
T1144
T1146
S1627
S1645
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S188
S192
S203
S208
S313
S315
S318
S321
T323
S324
S559
S564
T567
S624
S687
S891
T894
S901
S902
S904
S976
T977
S978
S981
S983
S984
S986
S989
S995
S1071
S1137
T1144
T1146
S1627
S1645
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.