ITPR2: inositol 1,4,5-trisphosphate receptor type 2
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S271 LRTTLRQS ATSATSS 1 17 - - - - - - 17 - - - - - - - - - - - - - T617 ITAKEIET FVSLLRR 1 9 - - - - - - - - - - - - 4 5 - - - - - - S620 KEIETFVS LLRRNRE 1 9 - - - - - - - - - - - - 4 5 - - - - - - S908 SSYFERLS KFQDGGN 1 8 - - - - - - 8 - - - - - - - - - - - - - S934 MMTQMVLS RGSIFPM 1 17 - - - - - - 17 - - - - - - - - - - - - - S937 QMVLSRGS IFPMSVP 3 80 - - - - 5 4 36 - - - - - - - 29 6 - - - - S1144 ENGEIGES QVKGGEE 2 71 - - - - 12 6 53 - - - - - - - - - - - - - S1160 IEESNILS PVQDGTK 10 749 24 - 22 19 16 20 73 - 108 62 45 41 47 44 28 5 95 40 49 11 S1568 TLFMKSHS NMVQRAA 1 8 - - - - - - 8 - - - - - - - - - - - - - S1581 AAMGWRLS ARSGPRF 2 16 8 - - - - - 8 - - - - - - - - - - - - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S271 LRTTLRQS ATSATSS - - - - - - - - - - - T617 ITAKEIET FVSLLRR - - - - - - - - - - - S620 KEIETFVS LLRRNRE - - - - - - - - - - - S908 SSYFERLS KFQDGGN - - - - - - - - - - - S934 MMTQMVLS RGSIFPM - - - - - - - - - - - S937 QMVLSRGS IFPMSVP - - - - - - - - - - - S1144 ENGEIGES QVKGGEE - - - - - - - - - - - S1160 IEESNILS PVQDGTK -6.2e-12 - -0.077 - - -3.5e-6 -8.6e-5 -4.3e-3 - -4.5e-8 0.069 S1568 TLFMKSHS NMVQRAA - - - - - - - - - - - S1581 AAMGWRLS ARSGPRF - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S271
T617
S620
S908
S934
S937
S1144
S1160
S1568
S1581
T1845
S1846
S1855
T1856
T1868
S1871
S1872
S1875
S1905
S2633
S2636
S2664
T2691
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S271 T617 S620 S908 S934 S937 S1144 S1160 S1568 S1581 T1845 S1846 S1855 T1856 T1868 S1871 S1872 S1875 S1905 S2633 S2636 S2664 T2691 protein RNA SCNV methylation CCRCC S271 T617 S620 S908 S934 S937 S1144 S1160 S1568 S1581 T1845 S1846 S1855 T1856 T1868 S1871 S1872 S1875 S1905 S2633 S2636 S2664 T2691 protein RNA SCNV methylation COAD S271 T617 S620 S908 S934 S937 S1144 S1160 S1568 S1581 T1845 S1846 S1855 T1856 T1868 S1871 S1872 S1875 S1905 S2633 S2636 S2664 T2691 protein RNA SCNV methylation GBM S271 T617 S620 S908 S934 S937 S1144 S1160 S1568 S1581 T1845 S1846 S1855 T1856 T1868 S1871 S1872 S1875 S1905 S2633 S2636 S2664 T2691 protein RNA SCNV methylation HNSCC S271 T617 S620 S908 S934 S937 S1144 S1160 S1568 S1581 T1845 S1846 S1855 T1856 T1868 S1871 S1872 S1875 S1905 S2633 S2636 S2664 T2691 protein RNA SCNV methylation LSCC S271 T617 S620 S908 S934 S937 S1144 S1160 S1568 S1581 T1845 S1846 S1855 T1856 T1868 S1871 S1872 S1875 S1905 S2633 S2636 S2664 T2691 protein RNA SCNV methylation LUAD S271 T617 S620 S908 S934 S937 S1144 S1160 S1568 S1581 T1845 S1846 S1855 T1856 T1868 S1871 S1872 S1875 S1905 S2633 S2636 S2664 T2691 protein RNA SCNV methylation OV S271 T617 S620 S908 S934 S937 S1144 S1160 S1568 S1581 T1845 S1846 S1855 T1856 T1868 S1871 S1872 S1875 S1905 S2633 S2636 S2664 T2691 protein RNA SCNV methylation PDAC S271 T617 S620 S908 S934 S937 S1144 S1160 S1568 S1581 T1845 S1846 S1855 T1856 T1868 S1871 S1872 S1875 S1905 S2633 S2636 S2664 T2691 protein RNA SCNV methylation UCEC S271 T617 S620 S908 S934 S937 S1144 S1160 S1568 S1581 T1845 S1846 S1855 T1856 T1868 S1871 S1872 S1875 S1905 S2633 S2636 S2664 T2691 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S271
T617
S620
S908
S934
S937
S1144
S1160
S1568
S1581
T1845
S1846
S1855
T1856
T1868
S1871
S1872
S1875
S1905
S2633
S2636
S2664
T2691
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S271
T617
S620
S908
S934
S937
S1144
S1160
S1568
S1581
T1845
S1846
S1855
T1856
T1868
S1871
S1872
S1875
S1905
S2633
S2636
S2664
T2691
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.