Protein: ENSP00000371321
Gene: RFC1

LinkedOmicsKB © 2022-2023 Zhang Lab

RFC1:
replication factor C subunit 1

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Structure

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S29KKNEKTKSDEETLKA7577----575999-28192423--32984368918
S69KKRIIYDSDSESEET1078338-1211263664-764560557569521327119518
S71RIIYDSDSESEETLQ96506-96748799-281644411815--9338679
S73IYDSDSESEETLQVK69732-77----6310898----7-
S108QDPVTYISETDEEDD10109196-3727838799-1086265604440186103439518
T110PVTYISETDEEDDFM969073-6754223154-241174677066--1474016
S156KTKNKPLSPIKLTPT101515122-103799710099-1086210899105977114101429018
T161PLSPIKLTPTSVLDY922616-443933--107151422197-3231-
T163SPIKLTPTSVLDYFG16------------------6-
S190ASKRKELSQNTDESG940433-44--46-39253531272448111654016
Showing 1 to 10 of 28 rows
102550
rows per page

Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S29KKNEKTKSDEETLKA-0.86--1.9e-6-0.380.056---2e-11-0.67
S69KKRIIYDSDSESEET2.6e-22--0.16-6.1e-121.8e-124.9e-17-0.0630.120.022
S71RIIYDSDSESEETLQ3.2e-4--2.1e-7-0.547.9e-12---5e-8-
S73IYDSDSESEETLQVK-----------
S108QDPVTYISETDEEDD1.2e-3--4.2e-33.1e-7-0.932.7e-164.1e-7--7.1e-4-2.5e-4
T110PVTYISETDEEDDFM9e-8--1.9e-30.74-0.873.7e-197.5e-16---0.2
S156KTKNKPLSPIKLTPT0.061-4.3e-35.2e-8--0.273.3e-30.751.5e-5-9.1e-16-0.15
T161PLSPIKLTPTSVLDY0.011--9.2e-6----0.41---
T163SPIKLTPTSVLDYFG-----------
S190ASKRKELSQNTDESG3.7e-6----3.5e-46.8e-43.5e-6-0.77--0.34
Showing 1 to 10 of 28 rows
102550
rows per page

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAS29S69S71S73S108T110S156T161T163S190T193S196S276S296S312S360S366S368S372T506S518S564S1088S1090S1093Y1095S1104S1106proteinRNASCNVmethylationCCRCCS29S69S71S73S108T110S156T161T163S190T193S196S276S296S312S360S366S368S372T506S518S564S1088S1090S1093Y1095S1104S1106proteinRNASCNVmethylationCOADS29S69S71S73S108T110S156T161T163S190T193S196S276S296S312S360S366S368S372T506S518S564S1088S1090S1093Y1095S1104S1106proteinRNASCNVmethylationGBMS29S69S71S73S108T110S156T161T163S190T193S196S276S296S312S360S366S368S372T506S518S564S1088S1090S1093Y1095S1104S1106proteinRNASCNVmethylationHNSCCS29S69S71S73S108T110S156T161T163S190T193S196S276S296S312S360S366S368S372T506S518S564S1088S1090S1093Y1095S1104S1106proteinRNASCNVmethylationLSCCS29S69S71S73S108T110S156T161T163S190T193S196S276S296S312S360S366S368S372T506S518S564S1088S1090S1093Y1095S1104S1106proteinRNASCNVmethylationLUADS29S69S71S73S108T110S156T161T163S190T193S196S276S296S312S360S366S368S372T506S518S564S1088S1090S1093Y1095S1104S1106proteinRNASCNVmethylationOVS29S69S71S73S108T110S156T161T163S190T193S196S276S296S312S360S366S368S372T506S518S564S1088S1090S1093Y1095S1104S1106proteinRNASCNVmethylationPDACS29S69S71S73S108T110S156T161T163S190T193S196S276S296S312S360S366S368S372T506S518S564S1088S1090S1093Y1095S1104S1106proteinRNASCNVmethylationUCECS29S69S71S73S108T110S156T161T163S190T193S196S276S296S312S360S366S368S372T506S518S564S1088S1090S1093Y1095S1104S1106proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.