SRGAP3: SLIT-ROBO Rho GTPase activating protein 3
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S129 NNVIVRLS QISEDVI 1 10 - - - - - - - - 7 3 - - - - - - - - - - S407 DAFQHSRS TESVKSA 2 16 7 - - - - - - - - - 5 4 - - - - - - - - T408 AFQHSRST ESVKSAA 1 9 - - - - - - - - - - 5 4 - - - - - - - - S410 QHSRSTES VKSAASE 2 25 7 - - - - - - - - - 10 8 - - - - - - - - S413 RSTESVKS AASETYM 6 249 7 - - - - - 72 - 53 30 5 5 - - - - 4 1 59 13 S416 ESVKSAAS ETYMSKI 2 43 - - - - - - 17 - - - - - - - - - - - 26 - S497 MRRPRPLS VYSHKLF 3 94 - - - - - - 63 - - - - - - - 15 2 - - 12 2 S556 EVNDIKNS FERGEDP 1 9 - - - - - - 9 - - - - - - - - - - - - - S718 GGEEYCDS PHSEPGA 1 8 - - - - - - 8 - - - - - - - - - - - - - S721 EYCDSPHS EPGAIDE 1 18 - - - - - - 18 - - - - - - - - - - - - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S129 NNVIVRLS QISEDVI - - - - - - - - - - - S407 DAFQHSRS TESVKSA - - - - - - - - - - - T408 AFQHSRST ESVKSAA - - - - - - - - - - - S410 QHSRSTES VKSAASE - - - - - - - - - - - S413 RSTESVKS AASETYM 0.16 - - - - 0.31 - - - - 0.32 S416 ESVKSAAS ETYMSKI - - - - - - - - - - - S497 MRRPRPLS VYSHKLF - - - - - - - - - - - S556 EVNDIKNS FERGEDP - - - - - - - - - - - S718 GGEEYCDS PHSEPGA - - - - - - - - - - - S721 EYCDSPHS EPGAIDE - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S129
S407
T408
S410
S413
S416
S497
S556
S718
S721
T735
T739
S740
S759
S808
S812
S817
S820
S821
S837
T839
S858
S868
S874
S895
S908
S919
S922
S932
S936
S948
S954
S1006
S1007
S1011
S1028
S1029
S1030
S1068
S1069
S1070
S1071
S1072
S1073
S1074
S1078
T1082
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S129 S407 T408 S410 S413 S416 S497 S556 S718 S721 T735 T739 S740 S759 S808 S812 S817 S820 S821 S837 T839 S858 S868 S874 S895 S908 S919 S922 S932 S936 S948 S954 S1006 S1007 S1011 S1028 S1029 S1030 S1068 S1069 S1070 S1071 S1072 S1073 S1074 S1078 T1082 protein RNA SCNV methylation CCRCC S129 S407 T408 S410 S413 S416 S497 S556 S718 S721 T735 T739 S740 S759 S808 S812 S817 S820 S821 S837 T839 S858 S868 S874 S895 S908 S919 S922 S932 S936 S948 S954 S1006 S1007 S1011 S1028 S1029 S1030 S1068 S1069 S1070 S1071 S1072 S1073 S1074 S1078 T1082 protein RNA SCNV methylation COAD S129 S407 T408 S410 S413 S416 S497 S556 S718 S721 T735 T739 S740 S759 S808 S812 S817 S820 S821 S837 T839 S858 S868 S874 S895 S908 S919 S922 S932 S936 S948 S954 S1006 S1007 S1011 S1028 S1029 S1030 S1068 S1069 S1070 S1071 S1072 S1073 S1074 S1078 T1082 protein RNA SCNV methylation GBM S129 S407 T408 S410 S413 S416 S497 S556 S718 S721 T735 T739 S740 S759 S808 S812 S817 S820 S821 S837 T839 S858 S868 S874 S895 S908 S919 S922 S932 S936 S948 S954 S1006 S1007 S1011 S1028 S1029 S1030 S1068 S1069 S1070 S1071 S1072 S1073 S1074 S1078 T1082 protein RNA SCNV methylation HNSCC S129 S407 T408 S410 S413 S416 S497 S556 S718 S721 T735 T739 S740 S759 S808 S812 S817 S820 S821 S837 T839 S858 S868 S874 S895 S908 S919 S922 S932 S936 S948 S954 S1006 S1007 S1011 S1028 S1029 S1030 S1068 S1069 S1070 S1071 S1072 S1073 S1074 S1078 T1082 protein RNA SCNV methylation LSCC S129 S407 T408 S410 S413 S416 S497 S556 S718 S721 T735 T739 S740 S759 S808 S812 S817 S820 S821 S837 T839 S858 S868 S874 S895 S908 S919 S922 S932 S936 S948 S954 S1006 S1007 S1011 S1028 S1029 S1030 S1068 S1069 S1070 S1071 S1072 S1073 S1074 S1078 T1082 protein RNA SCNV methylation LUAD S129 S407 T408 S410 S413 S416 S497 S556 S718 S721 T735 T739 S740 S759 S808 S812 S817 S820 S821 S837 T839 S858 S868 S874 S895 S908 S919 S922 S932 S936 S948 S954 S1006 S1007 S1011 S1028 S1029 S1030 S1068 S1069 S1070 S1071 S1072 S1073 S1074 S1078 T1082 protein RNA SCNV methylation OV S129 S407 T408 S410 S413 S416 S497 S556 S718 S721 T735 T739 S740 S759 S808 S812 S817 S820 S821 S837 T839 S858 S868 S874 S895 S908 S919 S922 S932 S936 S948 S954 S1006 S1007 S1011 S1028 S1029 S1030 S1068 S1069 S1070 S1071 S1072 S1073 S1074 S1078 T1082 protein RNA SCNV methylation PDAC S129 S407 T408 S410 S413 S416 S497 S556 S718 S721 T735 T739 S740 S759 S808 S812 S817 S820 S821 S837 T839 S858 S868 S874 S895 S908 S919 S922 S932 S936 S948 S954 S1006 S1007 S1011 S1028 S1029 S1030 S1068 S1069 S1070 S1071 S1072 S1073 S1074 S1078 T1082 protein RNA SCNV methylation UCEC S129 S407 T408 S410 S413 S416 S497 S556 S718 S721 T735 T739 S740 S759 S808 S812 S817 S820 S821 S837 T839 S858 S868 S874 S895 S908 S919 S922 S932 S936 S948 S954 S1006 S1007 S1011 S1028 S1029 S1030 S1068 S1069 S1070 S1071 S1072 S1073 S1074 S1078 T1082 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S129
S407
T408
S410
S413
S416
S497
S556
S718
S721
T735
T739
S740
S759
S808
S812
S817
S820
S821
S837
T839
S858
S868
S874
S895
S908
S919
S922
S932
S936
S948
S954
S1006
S1007
S1011
S1028
S1029
S1030
S1068
S1069
S1070
S1071
S1072
S1073
S1074
S1078
T1082
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
Loading, please wait
all sites
S129
S407
T408
S410
S413
S416
S497
S556
S718
S721
T735
T739
S740
S759
S808
S812
S817
S820
S821
S837
T839
S858
S868
S874
S895
S908
S919
S922
S932
S936
S948
S954
S1006
S1007
S1011
S1028
S1029
S1030
S1068
S1069
S1070
S1071
S1072
S1073
S1074
S1078
T1082
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.