Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
1q02 chain A
2jy7 chain A
2jy8 chain A
2k0b chain X
2knv chain A
2knv chain B
4mjs chain B
4mjs chain D
4mjs chain F
4mjs chain H
4mjs chain J
4mjs chain L
4mjs chain N
4mjs chain P
4mjs chain R
4mjs chain T
4mjs chain V
4mjs chain X
4uf8 chain A
4uf8 chain B
4uf8 chain C
4uf8 chain I
4uf9 chain A
4uf9 chain B
4uf9 chain D
5yp7 chain A
5yp7 chain D
5yp8 chain A
5yp8 chain B
5ypa chain A
5ypa chain B
5ypb chain A
5ypb chain B
5ypb chain C
5ypb chain D
5ypc chain A
5ypc chain B
5ypc chain C
5ypc chain D
5ype chain A
5ype chain B
5ype chain C
5ype chain D
5ypf chain A
5ypf chain B
5ypf chain C
5ypf chain D
5ypg chain A
5ypg chain B
5yph chain A
5yph chain B
6jm4 chain A
6jm4 chain B
6jm4 chain C
6jm4 chain D
6khz chain A
6khz chain B
6khz chain C
6khz chain D
6miu chain A
6miu chain B
6mj7 chain A
6tgy chain A
6th3 chain A
6th3 chain B
6th3 chain C
7r1o chain AAA
7r1o chain BBB
7r1o chain CCC
7r1o chain DDD
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S24 AREIRRFS FCCSPEP 10 538 41 - 25 8 59 48 88 - 22 14 5 5 38 37 27 7 29 12 60 13 S28 RRFSFCCS PEPEAEA 10 1174 114 - 94 72 4 5 81 - 84 50 103 93 101 91 63 13 71 28 89 18 S143 VGTRYKCS VCPDYDL 3 40 - - - - - - - - - - 5 4 9 8 - - - - 12 2 Y148 KCSVCPDY DLCSVCE 2 45 - - - - - - - - - - 15 14 8 8 - - - - - - S152 CPDYDLCS VCEGKGL 7 1036 - - 103 80 - - 90 - 91 52 103 91 93 82 - - 101 43 89 18 S182 LSEGFSHS RWLRKVK 1 9 - - - - - - 9 - - - - - - - - - - - - - S207 MGPPGNWS PRPPRAG 6 864 - - 95 75 - - 18 - 108 62 88 80 110 100 - - 92 36 - - S226 GPTAESAS GPSEDPS 3 76 - - 7 7 - - - - - - 9 8 25 20 - - - - - - S229 AESASGPS EDPSVNF 5 356 - - 70 49 - - - - - - 53 49 57 52 - - 8 4 14 - S233 SGPSEDPS VNFLKNV 7 453 - - 86 64 - - 18 - 17 11 78 72 47 40 - - 8 3 7 2
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S24 AREIRRFS FCCSPEP 0.11 - - 6.8e-8 - 0.6 - 0.019 - -0.002 -0.1 S28 RRFSFCCS PEPEAEA 9.3e-10 - 0.028 - - -3.5e-3 4.7e-11 2.0e-6 0.79 4.3e-4 0.071 S143 VGTRYKCS VCPDYDL - - - - - - - - - - - Y148 KCSVCPDY DLCSVCE - - - - - - - - - - - S152 CPDYDLCS VCEGKGL 5.7e-46 - 1.6e-4 - - 0.024 3.8e-19 1e-25 - 1.2e-5 5e-7 S182 LSEGFSHS RWLRKVK - - - - - - - - - - - S207 MGPPGNWS PRPPRAG 2.5e-13 - 0.02 - - 0.6 1.5e-6 6.1e-8 - 9.9e-4 - S226 GPTAESAS GPSEDPS 9.2e-3 - - - - - - 9.2e-3 - - - S229 AESASGPS EDPSVNF 1.4e-5 - 1.2e-3 - - - 0.11 7.4e-3 - - - S233 SGPSEDPS VNFLKNV -0.77 - 5.3e-7 - - - -6e-8 -0.92 - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S24
S28
S143
Y148
S152
S182
S207
S226
S229
S233
S249
S266
T269
S272
S275
S276
S277
T278
S282
S284
S287
S288
S291
S294
T304
S306
S328
S332
T339
S342
S349
T350
S355
S361
S365
S366
S370
S403
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S24 S28 S143 Y148 S152 S182 S207 S226 S229 S233 S249 S266 T269 S272 S275 S276 S277 T278 S282 S284 S287 S288 S291 S294 T304 S306 S328 S332 T339 S342 S349 T350 S355 S361 S365 S366 S370 S403 protein RNA SCNV methylation CCRCC S24 S28 S143 Y148 S152 S182 S207 S226 S229 S233 S249 S266 T269 S272 S275 S276 S277 T278 S282 S284 S287 S288 S291 S294 T304 S306 S328 S332 T339 S342 S349 T350 S355 S361 S365 S366 S370 S403 protein RNA SCNV methylation COAD S24 S28 S143 Y148 S152 S182 S207 S226 S229 S233 S249 S266 T269 S272 S275 S276 S277 T278 S282 S284 S287 S288 S291 S294 T304 S306 S328 S332 T339 S342 S349 T350 S355 S361 S365 S366 S370 S403 protein RNA SCNV methylation GBM S24 S28 S143 Y148 S152 S182 S207 S226 S229 S233 S249 S266 T269 S272 S275 S276 S277 T278 S282 S284 S287 S288 S291 S294 T304 S306 S328 S332 T339 S342 S349 T350 S355 S361 S365 S366 S370 S403 protein RNA SCNV methylation HNSCC S24 S28 S143 Y148 S152 S182 S207 S226 S229 S233 S249 S266 T269 S272 S275 S276 S277 T278 S282 S284 S287 S288 S291 S294 T304 S306 S328 S332 T339 S342 S349 T350 S355 S361 S365 S366 S370 S403 protein RNA SCNV methylation LSCC S24 S28 S143 Y148 S152 S182 S207 S226 S229 S233 S249 S266 T269 S272 S275 S276 S277 T278 S282 S284 S287 S288 S291 S294 T304 S306 S328 S332 T339 S342 S349 T350 S355 S361 S365 S366 S370 S403 protein RNA SCNV methylation LUAD S24 S28 S143 Y148 S152 S182 S207 S226 S229 S233 S249 S266 T269 S272 S275 S276 S277 T278 S282 S284 S287 S288 S291 S294 T304 S306 S328 S332 T339 S342 S349 T350 S355 S361 S365 S366 S370 S403 protein RNA SCNV methylation OV S24 S28 S143 Y148 S152 S182 S207 S226 S229 S233 S249 S266 T269 S272 S275 S276 S277 T278 S282 S284 S287 S288 S291 S294 T304 S306 S328 S332 T339 S342 S349 T350 S355 S361 S365 S366 S370 S403 protein RNA SCNV methylation PDAC S24 S28 S143 Y148 S152 S182 S207 S226 S229 S233 S249 S266 T269 S272 S275 S276 S277 T278 S282 S284 S287 S288 S291 S294 T304 S306 S328 S332 T339 S342 S349 T350 S355 S361 S365 S366 S370 S403 protein RNA SCNV methylation UCEC S24 S28 S143 Y148 S152 S182 S207 S226 S229 S233 S249 S266 T269 S272 S275 S276 S277 T278 S282 S284 S287 S288 S291 S294 T304 S306 S328 S332 T339 S342 S349 T350 S355 S361 S365 S366 S370 S403 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S24
S28
S143
Y148
S152
S182
S207
S226
S229
S233
S249
S266
T269
S272
S275
S276
S277
T278
S282
S284
S287
S288
S291
S294
T304
S306
S328
S332
T339
S342
S349
T350
S355
S361
S365
S366
S370
S403
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S24
S28
S143
Y148
S152
S182
S207
S226
S229
S233
S249
S266
T269
S272
S275
S276
S277
T278
S282
S284
S287
S288
S291
S294
T304
S306
S328
S332
T339
S342
S349
T350
S355
S361
S365
S366
S370
S403
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.