HDLBP: high density lipoprotein binding protein
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T28 PQQIKVAT LNSEEES 2 18 - - - - - - 8 - - - 5 5 - - - - - - - - S31 IKVATLNS EEESDPP 10 1199 79 - 49 38 97 100 99 - 75 42 93 85 47 40 76 17 105 44 95 18 S35 TLNSEEES DPPTYKD 10 894 122 - 78 64 24 29 36 - 18 9 88 80 56 49 34 8 66 29 95 9 S56 EKAACLES AQEPAGA 1 5 - - - - - - - - - - - - - - - - 4 1 - - S74 KIRPIKAS VITQVFH 2 14 - - - - - - - - - - 4 5 - - - - 3 2 - - S152 ARLQTQAS ATVAIPK 5 137 8 - - - - - - - - - 24 21 22 19 - - 17 9 17 - T271 NRTEIVFT GEKEQLA 1 10 - - - - - - - - - - 5 5 - - - - - - - - S317 VIGPKGNS LQEILER 8 450 46 - 4 4 - - 36 - 18 9 53 49 13 11 - - 92 38 66 11 S363 EVYAKANS FTVSSVA 5 76 8 - - - - - 18 - 7 3 - - 9 7 - - - - 18 6 Y437 DLINRMDY VEINIDH 8 707 78 - 64 41 2 7 44 - 40 21 59 56 85 76 - - 93 41 - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
T28 PQQIKVAT LNSEEES - - - - - - - - - - - S31 IKVATLNS EEESDPP 0.063 - 0.48 2.4e-4 - 0.14 2.7e-5 4.2e-4 -4.1e-4 -3.8e-4 -0.22 S35 TLNSEEES DPPTYKD 4.9e-3 - -8.2e-3 0.64 - - 1.5e-10 6.5e-7 - -3.6e-3 - S56 EKAACLES AQEPAGA - - - - - - - - - - - S74 KIRPIKAS VITQVFH - - - - - - - - - - - S152 ARLQTQAS ATVAIPK 6.6e-4 - - - - - 1.3e-3 0.11 - - - T271 NRTEIVFT GEKEQLA - - - - - - - - - - - S317 VIGPKGNS LQEILER -1 - - - - - 1.3e-4 - - -8.7e-11 7.6e-3 S363 EVYAKANS FTVSSVA - - - - - - - - - - - Y437 DLINRMDY VEINIDH -0.38 - -0.59 - - 0.92 0.21 1.7e-5 - -1.5e-12 -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
T28
S31
S35
S56
S74
S152
T271
S317
S363
Y437
S454
S551
S611
S622
S624
T626
S645
S667
S707
S727
S756
T842
T848
S894
S904
S944
S1236
S1237
S1238
S1245
S1246
S1247
S1252
T1261
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA T28 S31 S35 S56 S74 S152 T271 S317 S363 Y437 S454 S551 S611 S622 S624 T626 S645 S667 S707 S727 S756 T842 T848 S894 S904 S944 S1236 S1237 S1238 S1245 S1246 S1247 S1252 T1261 protein RNA SCNV methylation CCRCC T28 S31 S35 S56 S74 S152 T271 S317 S363 Y437 S454 S551 S611 S622 S624 T626 S645 S667 S707 S727 S756 T842 T848 S894 S904 S944 S1236 S1237 S1238 S1245 S1246 S1247 S1252 T1261 protein RNA SCNV methylation COAD T28 S31 S35 S56 S74 S152 T271 S317 S363 Y437 S454 S551 S611 S622 S624 T626 S645 S667 S707 S727 S756 T842 T848 S894 S904 S944 S1236 S1237 S1238 S1245 S1246 S1247 S1252 T1261 protein RNA SCNV methylation GBM T28 S31 S35 S56 S74 S152 T271 S317 S363 Y437 S454 S551 S611 S622 S624 T626 S645 S667 S707 S727 S756 T842 T848 S894 S904 S944 S1236 S1237 S1238 S1245 S1246 S1247 S1252 T1261 protein RNA SCNV methylation HNSCC T28 S31 S35 S56 S74 S152 T271 S317 S363 Y437 S454 S551 S611 S622 S624 T626 S645 S667 S707 S727 S756 T842 T848 S894 S904 S944 S1236 S1237 S1238 S1245 S1246 S1247 S1252 T1261 protein RNA SCNV methylation LSCC T28 S31 S35 S56 S74 S152 T271 S317 S363 Y437 S454 S551 S611 S622 S624 T626 S645 S667 S707 S727 S756 T842 T848 S894 S904 S944 S1236 S1237 S1238 S1245 S1246 S1247 S1252 T1261 protein RNA SCNV methylation LUAD T28 S31 S35 S56 S74 S152 T271 S317 S363 Y437 S454 S551 S611 S622 S624 T626 S645 S667 S707 S727 S756 T842 T848 S894 S904 S944 S1236 S1237 S1238 S1245 S1246 S1247 S1252 T1261 protein RNA SCNV methylation OV T28 S31 S35 S56 S74 S152 T271 S317 S363 Y437 S454 S551 S611 S622 S624 T626 S645 S667 S707 S727 S756 T842 T848 S894 S904 S944 S1236 S1237 S1238 S1245 S1246 S1247 S1252 T1261 protein RNA SCNV methylation PDAC T28 S31 S35 S56 S74 S152 T271 S317 S363 Y437 S454 S551 S611 S622 S624 T626 S645 S667 S707 S727 S756 T842 T848 S894 S904 S944 S1236 S1237 S1238 S1245 S1246 S1247 S1252 T1261 protein RNA SCNV methylation UCEC T28 S31 S35 S56 S74 S152 T271 S317 S363 Y437 S454 S551 S611 S622 S624 T626 S645 S667 S707 S727 S756 T842 T848 S894 S904 S944 S1236 S1237 S1238 S1245 S1246 S1247 S1252 T1261 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
T28
S31
S35
S56
S74
S152
T271
S317
S363
Y437
S454
S551
S611
S622
S624
T626
S645
S667
S707
S727
S756
T842
T848
S894
S904
S944
S1236
S1237
S1238
S1245
S1246
S1247
S1252
T1261
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
T28
S31
S35
S56
S74
S152
T271
S317
S363
Y437
S454
S551
S611
S622
S624
T626
S645
S667
S707
S727
S756
T842
T848
S894
S904
S944
S1236
S1237
S1238
S1245
S1246
S1247
S1252
T1261
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.