NCOA7: nuclear receptor coactivator 7
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
7obp chain A
7obp chain B
7obp chain C
7obp chain D
7obp chain E
7obp chain F
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S13 EKKERKQS YFARLKK 2 27 - - - - 4 5 18 - - - - - - - - - - - - - S89 TELKRYYS IDDNQNK 10 1502 122 - 103 80 76 85 99 - 108 62 103 95 110 101 83 19 101 42 95 18 T134 IALKFNIT PNKLVEL 5 66 8 - 4 4 - - - - 15 9 - - 4 4 - - 13 5 - - S162 LFVPDANS PSSTLRL 10 546 34 - 82 68 10 16 18 - 32 19 102 93 17 16 10 1 14 10 4 - S172 STLRLSSS SPGATVS 2 27 - - - - - - - - - - - - - - 15 3 - - 7 2 S173 TLRLSSSS PGATVSP 10 489 50 - 23 23 12 6 63 - 10 8 44 41 26 24 42 9 26 11 55 16 T177 SSSSPGAT VSPSSSD 7 135 14 - 9 8 5 4 - - - - 25 21 17 17 7 1 - - 5 2 S179 SSPGATVS PSSSDAE 10 1241 104 - 95 72 30 33 90 - 91 51 103 95 93 84 76 17 68 32 89 18 S181 PGATVSPS SSDAEYD 5 87 8 - 4 4 - - - - 11 6 18 17 - - - - 14 5 - - S182 GATVSPSS SDAEYDK 2 17 - - 4 4 4 5 - - - - - - - - - - - - - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S13 EKKERKQS YFARLKK - - - - - - - - - - - S89 TELKRYYS IDDNQNK -7.2e-20 - -0.049 -4.3e-11 - 0.11 -4.4e-9 -0.05 -1.4e-5 -1.2e-7 -0.16 T134 IALKFNIT PNKLVEL - - - - - - - - - - - S162 LFVPDANS PSSTLRL -0.15 - 3.5e-6 - - -1.4e-4 -9.4e-4 - - - - S172 STLRLSSS SPGATVS - - - - - - - - - - - S173 TLRLSSSS PGATVSP -0.074 - -5.6e-3 - - - -0.031 0.029 - -1.9e-4 0.013 T177 SSSSPGAT VSPSSSD 0.83 - - - - - 0.83 - - - - S179 SSPGATVS PSSSDAE -2.1e-10 - -4.1e-5 -0.06 - -0.99 -2.8e-13 -1.6e-3 0.7 -2.4e-4 0.078 S181 PGATVSPS SSDAEYD - - - - - - - - - - - S182 GATVSPSS SDAEYDK - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S13
S89
T134
S162
S172
S173
T177
S179
S181
S182
S183
S208
S209
T210
S211
T358
S366
S384
S395
S441
S500
S502
S562
S563
S565
S596
S609
S617
S670
T673
S760
Y764
Y765
S916
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S13 S89 T134 S162 S172 S173 T177 S179 S181 S182 S183 S208 S209 T210 S211 T358 S366 S384 S395 S441 S500 S502 S562 S563 S565 S596 S609 S617 S670 T673 S760 Y764 Y765 S916 protein RNA SCNV methylation CCRCC S13 S89 T134 S162 S172 S173 T177 S179 S181 S182 S183 S208 S209 T210 S211 T358 S366 S384 S395 S441 S500 S502 S562 S563 S565 S596 S609 S617 S670 T673 S760 Y764 Y765 S916 protein RNA SCNV methylation COAD S13 S89 T134 S162 S172 S173 T177 S179 S181 S182 S183 S208 S209 T210 S211 T358 S366 S384 S395 S441 S500 S502 S562 S563 S565 S596 S609 S617 S670 T673 S760 Y764 Y765 S916 protein RNA SCNV methylation GBM S13 S89 T134 S162 S172 S173 T177 S179 S181 S182 S183 S208 S209 T210 S211 T358 S366 S384 S395 S441 S500 S502 S562 S563 S565 S596 S609 S617 S670 T673 S760 Y764 Y765 S916 protein RNA SCNV methylation HNSCC S13 S89 T134 S162 S172 S173 T177 S179 S181 S182 S183 S208 S209 T210 S211 T358 S366 S384 S395 S441 S500 S502 S562 S563 S565 S596 S609 S617 S670 T673 S760 Y764 Y765 S916 protein RNA SCNV methylation LSCC S13 S89 T134 S162 S172 S173 T177 S179 S181 S182 S183 S208 S209 T210 S211 T358 S366 S384 S395 S441 S500 S502 S562 S563 S565 S596 S609 S617 S670 T673 S760 Y764 Y765 S916 protein RNA SCNV methylation LUAD S13 S89 T134 S162 S172 S173 T177 S179 S181 S182 S183 S208 S209 T210 S211 T358 S366 S384 S395 S441 S500 S502 S562 S563 S565 S596 S609 S617 S670 T673 S760 Y764 Y765 S916 protein RNA SCNV methylation OV S13 S89 T134 S162 S172 S173 T177 S179 S181 S182 S183 S208 S209 T210 S211 T358 S366 S384 S395 S441 S500 S502 S562 S563 S565 S596 S609 S617 S670 T673 S760 Y764 Y765 S916 protein RNA SCNV methylation PDAC S13 S89 T134 S162 S172 S173 T177 S179 S181 S182 S183 S208 S209 T210 S211 T358 S366 S384 S395 S441 S500 S502 S562 S563 S565 S596 S609 S617 S670 T673 S760 Y764 Y765 S916 protein RNA SCNV methylation UCEC S13 S89 T134 S162 S172 S173 T177 S179 S181 S182 S183 S208 S209 T210 S211 T358 S366 S384 S395 S441 S500 S502 S562 S563 S565 S596 S609 S617 S670 T673 S760 Y764 Y765 S916 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S13
S89
T134
S162
S172
S173
T177
S179
S181
S182
S183
S208
S209
T210
S211
T358
S366
S384
S395
S441
S500
S502
S562
S563
S565
S596
S609
S617
S670
T673
S760
Y764
Y765
S916
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S13
S89
T134
S162
S172
S173
T177
S179
S181
S182
S183
S208
S209
T210
S211
T358
S366
S384
S395
S441
S500
S502
S562
S563
S565
S596
S609
S617
S670
T673
S760
Y764
Y765
S916
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.