Protein: ENSP00000376333
Gene: LLGL2

LinkedOmicsKB © 2022-2023 Zhang Lab

LLGL2:
LLGL scribble cell polarity complex component 2

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Structure

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S480TDPNENFSAQGEDEW6742--8268----1086289817972--37143416
S495PPLRKVGSFDPYSDD16------------------6-
S680PGEAQEGSAKAERPG7842--9976--26-1710989010697--90367918
S808KSPDMQGSHQLLVVS126------------1412------
S847GSRVRRVSVAHFGSR7704--6158--27-7848103956457--49222814
S961APSRARNSGTQSDGE5420------9---58524846--83357118
T963SRARNSGTQSDGEEK237----------551512------
S965ARNSGTQSDGEEKQP5356--44------88794236--30163918
S1000TLEGDRGSGNWRSHR98119-447479--161171689285621487378216
S1015AAVGCSLSNGGAE__850672-33201934--493059542222--2484416
Showing 1 to 10 of 10 rows

Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S480TDPNENFSAQGEDEW-4.5e-43--3.9e-13---3e-14-3e-21-6.9e-12--0.3-0.14
S495PPLRKVGSFDPYSDD-----------
S680PGEAQEGSAKAERPG-9.1e-12--4.1e-11----1.1e-14-0.99--2.7e-50.001
S808KSPDMQGSHQLLVVS-----------
S847GSRVRRVSVAHFGSR-6.5e-44--9.8e-17---8.4e-8-4.2e-30-4.3e-14--7.3e-30.21
S961APSRARNSGTQSDGE-2.7e-40------3.7e-17-2.5e-15--1.3e-9-3.0e-5
T963SRARNSGTQSDGEEK-----------
S965ARNSGTQSDGEEKQP-1.5e-14------4.3e-8-0.19--7.7e-7-2.6e-4
S1000TLEGDRGSGNWRSHR-1.1e-16---2.7e-6---9.3e-23-1.1e-270.0249.0e-6-0.11
S1015AAVGCSLSNGGAE__-4.8e-13--3e-7--0.34-7.7e-9-7.9e-5---0.022
Showing 1 to 10 of 10 rows

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAS480S495S680S808S847S961T963S965S1000S1015proteinRNASCNVmethylationCCRCCS480S495S680S808S847S961T963S965S1000S1015proteinRNASCNVmethylationCOADS480S495S680S808S847S961T963S965S1000S1015proteinRNASCNVmethylationGBMS480S495S680S808S847S961T963S965S1000S1015proteinRNASCNVmethylationHNSCCS480S495S680S808S847S961T963S965S1000S1015proteinRNASCNVmethylationLSCCS480S495S680S808S847S961T963S965S1000S1015proteinRNASCNVmethylationLUADS480S495S680S808S847S961T963S965S1000S1015proteinRNASCNVmethylationOVS480S495S680S808S847S961T963S965S1000S1015proteinRNASCNVmethylationPDACS480S495S680S808S847S961T963S965S1000S1015proteinRNASCNVmethylationUCECS480S495S680S808S847S961T963S965S1000S1015proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.