Protein: ENSP00000376403
Gene: GPRC5C

LinkedOmicsKB © 2022-2023 Zhang Lab

GPRC5C:
G protein-coupled receptor class C group 5 member C

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S311TKSSPEQSYQGDMYP17--------34----------
Y312KSSPEQSYQGDMYPT17--------34----------
Y324YPTRGVGYETILKEQ6563--72681917------978934763305116
T326TRGVGYETILKEQKG7886--99763231----938511010071105428916
S335LKEQKGQSMFVENKA5539--9572------302710292--4821457
S344FVENKAFSMDEPVAA9790--9572459-58336357106967149229518
S356VAAKRPVSPYSGYNG5117----4518-----54--3918204
Y358AKRPVSPYSGYNGQL588--98----1591081213----4-
S359KRPVSPYSGYNGQLL110----------55--------
Y370GQLLTSVYQPTEMAL231--178--------------6-
Showing 1 to 10 of 19 rows
1025
rows per page

Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S311TKSSPEQSYQGDMYP-----------
Y312KSSPEQSYQGDMYPT-----------
Y324YPTRGVGYETILKEQ-2.6e-4--5.3e-23----3.3e-13-2.0e-65.1e-4
T326TRGVGYETILKEQKG-0.55--1e-210.073---4.7e-192e-10-3.9e-111.8e-3
S335LKEQKGQSMFVENKA-1.8e-4--3.7e-18----1.6e-91.5e-3-5.2e-5-
S344FVENKAFSMDEPVAA0.012--2.3e-10--0.260.925.1e-11-0.11.9e-3
S356VAAKRPVSPYSGYNG-0.79---------0.79-
Y358AKRPVSPYSGYNGQL-----------
S359KRPVSPYSGYNGQLL-----------
Y370GQLLTSVYQPTEMAL-----------
Showing 1 to 10 of 19 rows
1025
rows per page

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAS311Y312Y324T326S335S344S356Y358S359Y370S383Y387S398S403S406T407Y414T423S431proteinRNASCNVmethylationCCRCCS311Y312Y324T326S335S344S356Y358S359Y370S383Y387S398S403S406T407Y414T423S431proteinRNASCNVmethylationCOADS311Y312Y324T326S335S344S356Y358S359Y370S383Y387S398S403S406T407Y414T423S431proteinRNASCNVmethylationGBMS311Y312Y324T326S335S344S356Y358S359Y370S383Y387S398S403S406T407Y414T423S431proteinRNASCNVmethylationHNSCCS311Y312Y324T326S335S344S356Y358S359Y370S383Y387S398S403S406T407Y414T423S431proteinRNASCNVmethylationLSCCS311Y312Y324T326S335S344S356Y358S359Y370S383Y387S398S403S406T407Y414T423S431proteinRNASCNVmethylationLUADS311Y312Y324T326S335S344S356Y358S359Y370S383Y387S398S403S406T407Y414T423S431proteinRNASCNVmethylationOVS311Y312Y324T326S335S344S356Y358S359Y370S383Y387S398S403S406T407Y414T423S431proteinRNASCNVmethylationPDACS311Y312Y324T326S335S344S356Y358S359Y370S383Y387S398S403S406T407Y414T423S431proteinRNASCNVmethylationUCECS311Y312Y324T326S335S344S356Y358S359Y370S383Y387S398S403S406T407Y414T423S431proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.